고상추출법-UHPLC-MS/MS를 이용한 금강 수계 내 신종 유기오염물질 분석
Determination of Emerging Organic Pollutants in Geum River Using SPE Coupled with UHPLC-MS/MS
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The occurrence and concentration of emerging organic pollutants, organophosphorus flame retardants (OPFRs), benzotriazole UV stabilizers (BUVSs), pharmaceuticals and personal care products (PPCPs) were investigated using SPE coupled with UHPLC-MS/MS. The method detection limit (MDL) and quantification limit (MQL) for target compounds (10 OPFRs, 8 BUVSs, 9 PPCPs) was lower than 4.6 ng/L and 15 ng/L, respectively, while the recovery rate for river water matrix was ranged from 71 to 100%. Among 27 target pollutants, 18 chemicals were successfully quantified with ng/L levels ranged from 0.3 ng/L ~ 36.9 ng/L. Tributyl phosphate (TnBP; 27.7 ng/L), 2-(2H-benzotrizole-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol (UV-234; 1.6 ng/L), and Methyl paraben (MeP; 36.9 ng/L) are the most abundant compound measured at the highest concentration for each pollutants group, respectively. Carbamazepine (CBZ) and MeP showed the highest detection frequency (97%), followed by 77% frequency of triphenyl phosphate (TPhP) and propyl paraben (PrP). The concentration determined for target organic pollutants are far below a level to trigger an acute toxicity on aquatic organisms. However, the information on the occurrence and concentration gathered from chemical monitoring with a reliable analytical technique should be enlarged to expand our knowledge on integrity and safety of aquatic ecosystem.
Abstract
The occurrence and concentration of emerging organic pollutants, organophosphorus flame retardants (OPFRs), benzotriazole UV stabilizers (BUVSs), pharmaceuticals and personal care products (PPCPs) were investigated using SPE coupled with UHPLC-MS/MS. The method detection limit (MDL) and quantification limit (MQL) for target compounds (10 OPFRs, 8 BUVSs, 9 PPCPs) was lower than 4.6 ng/L and 15 ng/L, respectively, while the recovery rate for river water matrix was ranged from 71 to 100%. Among 27 target pollutants, 18 chemicals were successfully quantified with ng/L levels ranged from 0.3 ng/L ~ 36.9 ng/L. Tributyl phosphate (TnBP; 27.7 ng/L), 2-(2H-benzotrizole-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol (UV-234; 1.6 ng/L), and Methyl paraben (MeP; 36.9 ng/L) are the most abundant compound measured at the highest concentration for each pollutants group, respectively. Carbamazepine (CBZ) and MeP showed the highest detection frequency (97%), followed by 77% frequency of triphenyl phosphate (TPhP) and propyl paraben (PrP). The concentration determined for target organic pollutants are far below a level to trigger an acute toxicity on aquatic organisms. However, the information on the occurrence and concentration gathered from chemical monitoring with a reliable analytical technique should be enlarged to expand our knowledge on integrity and safety of aquatic ecosystem.
참고문헌 (21)
- S. Rodriguez-Mozaz., "Advantages and limitations of on-line solid phase extraction coupled to liquid chromatography-mass spectrometry technologies versus biosensors for monitoring of emerging contaminants in water", Journal of Chromatography A, 1152, pp.97~115 (2007)
- M. La Farre., "Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment", Trends in Analytical Chemistry, 27, pp.991~1007 (2008)
- L. Sanchez-Prado., "Microwave-assisted extraction : Application to the determination of emerging pollutants in solid samples", Journal of Chromatography A, 1217, pp.2390~2414 (2010)
- R. Tanoue., "Simultaneous determination of polar pharmaceuticals and personal care products in biological organs and tissues", Journal of Chromatography A, 1355, pp.193~205 (2014)
- Y. Kameda., "Occurrence and profiles of organic sun-blocking agents in surface waters and sediments in Japanese rivers and lakes", Environmental Pollution, 159, pp.1570~1576 (2011)
- J. Meyer., "Organophosphate flame retardants and plasticizers in wastewater treatment", Journal of Environmental Monitoring, 6, pp.599~605 (2004)
- "Flame retardants, The case for policy change 2013", Environment & Human Health, Inc., ~
- "Stockholm Convention on Persistent Organic Pollutants. Draft risk management evaluation for commercial pentabromodiphenyl ether" (2007)[URL]
- J. W. Kim., "Organophosphorus flame retardants in house dust from the Philppines : occurrence and assessment of human exposure", Environmental Science and Pollution Research, 20, pp.812~822 (2013)
- E. Gracia-Lor., "Simultaneous determination of acidic, neutral and basic pharmaceuticals in urban wastewater by ultra highpressure liquid chromatography-tandem mass spectrometry", Journal of Chromatography A, 1217, pp.622~632 (2010)
- J. Wu., "Study on the matrix effect in the determination of selected pharmaceutical residues in seawater by solid-phase extraction and ultra-high-performance liquid chromatography-electrospray ionization low-energy collision-induced dissociation tandem mass spectrometry", Journal of Chromatography A, 1217, pp.1471~1475 (2010)
- J. W. Kim., "Comprehensive determination of pharmaceuticals, personal care products, benzotriazole UV stabilizers and organophosphorus flame retardants in environmental water samples using SPE Coupled with UHPLC-MS", MS, 2015, pp.11, 138~149
- 제4차 화학물질 유통량조사, "환경부", ~ (2012)
- E. Martinez-Carballo., "Determination of selected organophosphate esters in the aquatic environment of Austria", Science of the Total Environment, 388, pp.290~299 (2007)
- J. W. Kim., "Organophosphorus flame retardants(PFRs)in human breast milk from several Asian countries", Chemosphere, 116, pp.91~97 (2014)
- R. Liu., "Determination of nine benzotriazole UV stabilizers in environmental water samples by automated on-line solid ohase extraction coupled with high-performance liquid chromatography-tandem mass spectrometry", Talanta, 120, pp.158~166 (2014)
- "Ministry of the Environment Government of Japan" (2006)[URL]
- Y. Zhang., "Carbamazepine and diclofenac : removal in wastewater treatment plants and occurrence in water bodies", Chemosphere, 73, pp.1151~1161 (2008)
- N. Nakada., "Occurrence of 70 Pharmaceutical and personal care products in Tone River Basin in Japan", Water Science and Technology, pp.133~140 (2007)
- 환경부, "하천 퇴적물 중 POPs 축적도 모니터링사업(II): 금강수계", ~ (2008)
- J. A. Andresen., "Organophosphorus flame retardants and plasticizers in surface waters", Science of the Total Environment, 332, pp.155~166 (2004)