용융전기방사를 이용한 PLA/TiO2 나노섬유의 개발
Fabrication of PLA/TiO2 nanofibers using melt-electro-spinning
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다운로드
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참고문헌
키워드
초록
전기방사법을 이용하여 제조된 웹은 높은 비표면적 및 다공성으로 약물전달시스템에 적용하고자 널리 연구 되어지고 있다. 본 연구에서는 생체적합성을 가진 생분해성 고분자 Poly(lactic acid))(PLA)와 생체안정성을 가지는 재료인TiO2를 이용하여 복합소재를 제작하였다. 인체에 유해한 용매인 chloroform이 포함되어 있지 않은 복합화를 위하여 용융전기방사법을 이용하여 나노섬유를 제작하였다. 이렇게 제조된 PLA/TiO2 web을 scanning electron microscope(SEM)와 field emission transmission electron microscope(FE-TEM)을 이용하여 섬유의 모양을 확인하였고, X-ray diffractometer(XRD)를 이용하여 PLA/TiO2 web의 결정구조를 분석하였다.
Abstract
Electrospun webs have been widely investigated for applying to drug delivery system (DDS) because of their high specific surface area and high porosity. In this study, the composite webs of PLA (poly(lactic acid)) and TiO2 were fabricated by melt-electro-spinning method for applying to drug delivery system. The morphologies of PLA/TiO2 webs were observed using scanning electron microscope (SEM) and field emission transmission electron microscope (FE-TEM). The crystal structures of PLA/TiO2 composite webs were confirmed by X-ray diffractometer (XRD).
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