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유산소와 저항성의 복합운동이 대사증후군 중년여성의 인슐린저항성, C-반응성 단백 및 체력에 미치는 영향

Effects of Aerobic and Resistance Exercise on Insulin Resistance, C-reactive Protein, and Physical Fitness in Middle-aged Women with Metabolic Syndrome

강설중|김종휴|노종철
대한운동학회 (Korean Acadaemy of Kinesiology)|2013.04|아시아 운동학 학술지 (The Asian Journal of Kinesiology)|제15권 제2호|pp. 81-91|DOI 10.15758/jkak.2013.15.2.81

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참고문헌

키워드

대사증후군C-reactive proteinMetabolic syndromePhysical fitness체력인슐린저항성복합운동Insulin resistanceC-반응성 단백Aerobic and resistance exercise

초록

[서론] 본 연구는 유산소와 저항성의 복합운동이 대사증후군 중년여성의 인슐린저항성, C-반응성 단백 및 체력 변화에 대한 것이다. [방법] 연구대상자는 대사증후군으로 진단된 중년여성을 운동군(n=10)과 대조군(n=10)으로 구분하여 12주간 주 3회, 유산소 운동(30분)과 저항성 운동(30분)을 실시하였다. [결과] 첫째, 복합운동에 의해 비만지표(체중, 체지방율, 허리둘레), 유리지방산, 중성지방 및 수축기와 이완기 혈압은 유의하게 감소되었으며 HDL-콜레스테롤은 유의하게 증가되었다. 둘째, 복합운동에 의해 혈당과 인슐린 수치를 낮추어 인슐린저항성 지표, HOMA-IR이 유의하게 감소되었다. 셋째, 복합운동에 의해 C-반응성 단백은 유의하게 감소하였다. 넷째, 복합운동에 의해 심폐지구력, 근력 및 근지구력은 유의하게 증가되었다. [결론] 유산소와 저항성의 복합운동은 대사증후군 관리에 유용한 운동 프로그램으로 적용할 수 있다고 생각된다.

Abstract

[INTRODUCTION] The purpose of this study was to investigate the effects of aerobic and resistance exercise on insulin resistance, C-reactive protein, and physical fitness in middle-aged women with metabolic syndrome. [METHOD] Participants were randomly assigned combine exercise group(n=10), and control exercise group(n=10). The exercise group performed for 60 min(consisting of aerobic exercise for 30 min and resistance exercise 30 min) per day, for 3 day per, week for 12 weeks. Metabolic risk factor, insulin resistance, C-reactive protein and physical fitness were measured at before and after 12 weeks from each group. [RESULT] First, The metabolic syndrome risk factors(weight, %fat, waist circumference, systolic blood pressure, diastolic blood pressure, triglyceride, and HDL-Cholesterol) were significantly improved after 12 weeks exercise program. Second, The blood glucose, insulin, and HOMA-IR were significantly decreased after 12 weeks exercise program. Third, The C-reactive were significantly decreased after 12 weeks exercise program. Fourth, The physical fitness(VO2max, muscle strength and muscle endurance) were significantly increased after 12 weeks exercise program. [CONCLUSION] Combined exercise program has beneficial effects on insulin resistance, C-reactive, and physical fitness in middle-aged women with metabolic syndrome.

참고문헌 (53)

  1. 고성식, "복합운동 트레이닝 유형이 중년여성의 건강체력과 신체구성 및 대사증후군 지표에 미치는 영향", 한국발육발달학회지, 17(2), pp.89~97 (2009), 한국발육발달학회
  2. 김기진, "중년여성의 유산소·저항성 운동 후 체지방량 및 심폐기능 변화에 따른 혈중 CRP 농도 및 HOMA-IR의 변화 비교", 운동과학, 18(3), pp.317~328 (2009), 한국운동생리학회
  3. 김연수, "운동과 영양교육이 대사성 증후군의 인슐린 저항성과 심폐기능 및 신체구성에 미치는 영향", 체육과학연구, 16(2), pp.54~61 (2005), 국민체육진흥공단 부설 한국스포츠개발원
  4. 이동훈, "6주간의 복합운동을 포함한 생활습관 중재요법이 제2형 당뇨병 환자의 대사지표와 대혈관 합병증 위험도에 미치는 영향", 대한비만학회지, 20(3), pp.147~159 (2011), 대한비만학회
  5. 임강일, "비만과 당뇨비만 여성들의 아디포사이토카인, 인슐린 저항성 및인슐린 분비능에 대한 복합운동 트레이닝의 효과", 운동과학, 15(3), pp.229~240 (2006), 한국운동생리학회
  6. American College of Sports Medicine, "American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise", Medicine and Science in Sports and Exercise, 43(7), pp.1334~1359 (2011)
  7. American Diabetes Association., "Standards of Medical Care in Diabetes", Diabetes Care, 28(11), pp.4~36 (2006)
  8. Arner, P., "Insulin resistance in type 2 diabetes: role of fatty acids", Diabetes Metabolism Research Review, 18, pp.5~9 (2002)
  9. Bateman, L. A., "Comparison of aerobic versus resistance exercise training effects on metabolic syndrome(from the studies of a Targeted Risk Reduction Intervention Through Defined Exercise-Strride-AT", RT), 2011, pp.108(6), 838~844
  10. Boden, G., "Obesity, insulin resistance and free fatty acids. Current Opinion in Endocrinology", Diabetes and Obesity, 182(2), pp.139~143 (2011)
  11. Cuff, D. J., "Effective exercise modality to reduce insulin resistance in women with type 2 diabetes", Diabetes Care, 26, pp.2977~2982 (2003)
  12. Fatone, C., "Two weekly sessions of combined aerobic and resistance exercise are sufficient to provide beneficial effects in subjects with Type 2 diabetes mellitus and metabolic syndrome", Journal of Endocrinology Investigation, 33(7), pp.489~495 (2010)
  13. Fazelifar, S., "Effect of endurance and resistance training on C-reactive protein obese children", Annal of Biological Research, 2(6), pp.233~239 (2011)
  14. Felber, J. P., "From Obesity to Diabetes" (1993), John Wiley
  15. Ho, S. S., "The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obesity in a randomized trail", BMC Public Health, 12(704), pp.1~10 (2012)
  16. Holten, M. K., "Strength training increased insulin mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes", Diabetes, 53, pp.294~305 (2004)
  17. Horwitz, J. F., "Exercise-induced alterations in muscle lipid metabolism improvement insulin sensitivity", Exercise Sports Science Review, 35, pp.192~196 (2007)
  18. Hotamisligil, G. S., "Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance", Journal of Clinical Investigation, 95, pp.2409~2415 (1995)
  19. International Diabetes Federation, "The IDF consensus worldwide definition of the metabolic syndrome", ~ (2005)
  20. Janssen, I., "Effects of an energy-resistance diet with or without exercise on abdominal fat, intermuscular fat and, metabolic risk factor in obese women", Diabetes Care, 25, pp.431~438 (2002)
  21. Jorge, M. L., "The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokine, and muscle insulin signaling in patients with type 2 diabetes mellitus", Metabolism, 60(9), pp.1244~1252 (2011)
  22. Jurca, R., "Association of muscular strength with incidence of metabolic syndrome in men", Medicine Science Sports Exercise, 37(11), pp.1849~1855 (2005)
  23. Karvonen, M. J., "The effect of training of heart rate: A longitudinal study", Annales Medicine Experimentalis at Biologiae Fenniae, 35, pp.307~315 (1957)
  24. Katzmarzyk, P. T., "Targeting the metabolic syndrome with exercise: evidence from the HERITAGE Family Study", Medicine and Science in Sports and Exercise, 35, pp.1703~1709 (2003)
  25. Kelly, D. E., "Effects of physical activity on insulin action and glucose tolerance in obesity", Medicine and Science in Sports and Exercise, 31, pp.619~623 (1999)
  26. Kelly, D. E., "The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transporter and phosphorylation in skeletal muscle", Journal of Clinical Investigation, 97, pp.2705~2713 (1996)
  27. Kullo, I. J., "Relation of low cardiorespiratory fitness to the metabolic syndrome in middle-aged men", American Journal of Cardiology, 90, pp.795~797 (2002)
  28. Lakka, H. M., "The metabolic syndrome and total cardiovascular disease mortality in middle-aged men", Journal of American Medicine Association, 288, pp.2709~2716 (2002)
  29. LaMonte, C. F., "Cardiorespiratory fitness is inversely associated with the incident metabolic syndrome: a prospective study of men and women", Circulation, 25, pp.505~512 (2005)
  30. Lsskdonen, D. E., "Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome", Diabetes Care, 25, pp.1612~1618 (2002)
  31. Maiorana, A., "Combine aerobic and resistance exercise improvement gycemic control and fitness in type 2 daibetes", Diabetes Research and Clinical Practice, 56, pp.115~123 (2002)
  32. Matthewa, D. R., "Homeostasis model assessment insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man", Diabetology, 28, pp.412~419 (1985)
  33. Meshkani, R., "Hepatic insulin resistance, metabolic syndrome and cardiovascular disease", Clinical Biochemistry, 42, pp.1331~1346 (2009)
  34. National Cholesterol Education Program., "Executive Summary of the Third Report of National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults(Adults Treatment Panel Ⅲ)", Journal of American Medicine Association, 285, pp.2486~2497 (2001)
  35. O'Donovan, G., "The effects 24 weeks of moderate- or highintensity exercise on insulin resistance", European Journal Applied Physiology, 118, pp.346~354 (2005)
  36. Pedersen, B. K., "The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control", The Biochemical Society, 42, pp.105~117 (2006)
  37. Pirro, M., "Plasma fatty acid levels and risk of ischemic heart disease: prospective results from the Quebec Cardiovascular Study", Atherosclerosis, 160, pp.377~384 (2002)
  38. Plaisance, E. P., "Physical activity and high-sensitivity C-reactive protein", Sports Medicine, 36(5), pp.443~458 (2006)
  39. Poehlman, E. T., "Effects of endurance and resistance training on total daily energy expenditure in young women: a controlled randomized trial", Journal of Clinical Endocrinology and Metabolism, 87, pp.1004~1009 (2002)
  40. Reaven, G. M., "Role of insulin resistance in human disease", Diabetes, 37, pp.1595~1607 (1988)
  41. Ridker, P. M., "C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events", Circulation, 107, pp.391~397 (2003)
  42. Rohde, L. E., "Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men", American Journal Cardiology, 84, pp.1018~1022 (1999)
  43. Sanz, C., "Physical exercise for the prevention and treatment of type 2 diabetes", Diabetes Metabolism, 36, pp.346~351 (2010)
  44. Seo, D. I., "Effects of 12 weeks of combined exercise training on visfatin and metabolic syndrome factors in obese middle-aged women", Journal of Sports Science and Medicine, 10, pp.222~226 (2011)
  45. Shulman, G. I., "Cellular mechanism of insulin resistance", Journal of Clinical Investigation, 106(2), pp.171~176 (2000)
  46. Snowling, N. L., "Effects of different models of exercise training on gulcose control and risk factor for complications in type 2 diabetic patients: a meta analysis", Diabetes Care, 29, pp.2518~2527 (2006)
  47. Tchernof, A., "Weight loss reduces C-reactive protein levels in obese postmenopausal women", Circulation, 105, pp.564~569 (2002)
  48. Unger, R. H., "Lipid homeostasis, lipotoxicity and the metabolic syndrome", Biochemica et Biophysica Acta, 3, pp.209~214 (2010)
  49. Yudkin, J. S., "C-reactive protein in heathy subjects: associated with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?", Arteriosclerosis Thrombosis Vascular and Biology, 19(4), pp.972~978 (1999)
  50. Wei, M., "Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men", Journal of American Medicine Association, 282, pp.1547~1553 (1999)
  51. Willis, L. H., "Effects of aerobic", or resistance training on body mass and fat mass in overweight or obese adults, 2012, pp.113, 1831~1837
  52. Wilson, A. M., "The novel role of C-reactive protein in cardiovascular disease: Risk marker or pathogen", International Journal of Cardiology, 106, pp.291~297 (2006)
  53. World Health Organization, "Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO Consultation. Part 1: diagnosis and classification of diabetes mellitus" (1999), World Health Organization

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