만성전립선염/만성골반통증후군과 비뇨생식기 마이코플라즈마 및 클라미디아 감염과의 관계
Correlation between Genitourinary Mycoplasmas and Chlamydia Infection and Chronic Prostatitis/Chronic Pelvic Pain Syndrome
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Purpose: Chronic prostatitis frequently occurs in men of all ages. Recent studies suggest that fastidious microorganisms may play a role in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The aim of this study was to investigate if correlation exists between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. Materials and Methods: We evaluated Mycoplasmas and Chlamydia prostatitis in 222 patients diagnosed with CP/CPPS from November 2008 to January 2011 by using the Chlamydia and Mycoplasma IST2 kits. Results: Of the 222 patients, 33 (14.9%) and 189 (85.1%) were respectively classified category IIIa (inflammatory CP/CPPS) and IIIb (non-inflammatory CP/CPPS). On kit tests, 10 (30.3%) of the 33 category IIIa and 55 (29.1%) of the 189 category IIIb cases were positive for causative microorganism. Conclusions: The results suggest close correlation between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. In addition, the Chlamydia and Mycoplasma IST2 kits may be useful for simple detection of fastidious microorganisms in CP/CPPS.
Abstract
Purpose: Chronic prostatitis frequently occurs in men of all ages. Recent studies suggest that fastidious microorganisms may play a role in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The aim of this study was to investigate if correlation exists between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. Materials and Methods: We evaluated Mycoplasmas and Chlamydia prostatitis in 222 patients diagnosed with CP/CPPS from November 2008 to January 2011 by using the Chlamydia and Mycoplasma IST2 kits. Results: Of the 222 patients, 33 (14.9%) and 189 (85.1%) were respectively classified category IIIa (inflammatory CP/CPPS) and IIIb (non-inflammatory CP/CPPS). On kit tests, 10 (30.3%) of the 33 category IIIa and 55 (29.1%) of the 189 category IIIb cases were positive for causative microorganism. Conclusions: The results suggest close correlation between genitourinary Mycoplasmas and Chlamydia infections and CP/CPPS. In addition, the Chlamydia and Mycoplasma IST2 kits may be useful for simple detection of fastidious microorganisms in CP/CPPS.
참고문헌 (19)
- Collins MM, "How common is prostatitis? A national survery of physician visits", J Urol, 159, pp.1224~1228 (1998)
- Woo YN, "Prostatitis", Korean J Urol, 35, pp.575~585 (1994)
- Krieger JN, "Chronic pelvic pains represent the most prominent urogenital symptoms of chronic prostatitis", Urology, 48, pp.715~721 (1996)
- Krieger NJ, "NIH consensus definition and classification of prostatitis", JAMA, 282, pp.236~237 (1999)
- Berger RE, "Bacteria in the prostate tissue of men with idiopathic prostatic inflammation", J Urol, 157, pp.863~865 (1997)
- Ponniah S, "PSA is a candidate self-antigen in autoimmune chronic prostatitis", chronic pelvic pain syndrome, 2000, pp.44, 49~54
- Zermann DH, "Neurourological insights into the etiology of genitourinary pain in men", J Urol, 161, pp.903~908 (1999)
- Mehik A, "Fears, sexual disturbances and personality features in men with prostatitis: a population- based cross-sectional study in Finland", BJU Int, 88, pp.35~38 (2001)
- 하재성, "만성 골반통 증후군에서 중합효소 연쇄반응을 이용한 잠복 미생물의 검출", Korean Journal of Urology, 43(5), pp.396~401 (2002), 대한비뇨기과학회
- Blacklock NJ, "Anatomical factors in prostatitis", Br J Urol, 46, pp.47~54 (1974)
- Kim SW, "The diagnostic values of the polymerase chain reaction in prostatitis", Korean J Infect Dis, 32, pp.265~273 (2000)
- Krieger JN, "Prokaryotic DNA sequences in patients with chronic idiopathic prostatitis", J Clin Microbiol, 34, pp.3120~3128 (1996)
- Moulder JW, "Characteristics of Chlamydia, in the Microbiology of chlamydia", pp.4~19 (1988), CRC Press
- Razin S, "Molecular biology and pathogenicity of mycoplasma", Microbiol Mol Biol Rev, 62, pp.1094~1156 (1998)
- Fraser DM, "The minimal gene complement of Mycoplasma genitalium", Science, 270, pp.397~403 (1995)
- Razin S, "Highlights of mycoplasma research an historical perspective", Biologicals, 38, pp.183~190 (2010)
- Rosengarten R, "Host-pathogen interactions in mycoplasma pathogenesis: virulence and survival strategies of minimalist prokaryotes", Int J Med Microbiol, 290, pp.15~25 (2000)
- Taylor-robinson D, "Genital mycoplasma infections", Clin Lab Med, 9, pp.501~523 (1989)
- Elnifro EM, "Multiplex PCR: optimization and application in diagnostic virology", Clin Microbiol Rev, 13, pp.559~570 (2000)