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Differences in Urine Microbiome of Acute Cystitis and Chronic Recurrent Cystitis in Women

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초록

The diagnosis of urinary tract infection (UTI) relies on urine culture tests to identify aerobic or anaerobic urinary tract pathogens. This method has limitations in identifying anaerobic bacteria, and there is uncertainty in identifying all bacteria. A new next-generation sequencing (NGS) method has gradually helped overcome these limitations, and the microorganisms present in the human urinary tract are gradually being revealed. This review introduces studies on the microbiome analyzed using NGS of urine from patients with acute cystitis and recurrent UTIs and discusses whether NGS may reveal the pathophysiology of the disease.

Abstract

The diagnosis of urinary tract infection (UTI) relies on urine culture tests to identify aerobic or anaerobic urinary tract pathogens. This method has limitations in identifying anaerobic bacteria, and there is uncertainty in identifying all bacteria. A new next-generation sequencing (NGS) method has gradually helped overcome these limitations, and the microorganisms present in the human urinary tract are gradually being revealed. This review introduces studies on the microbiome analyzed using NGS of urine from patients with acute cystitis and recurrent UTIs and discusses whether NGS may reveal the pathophysiology of the disease.

참고문헌 (35)

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