본문 바로가기
KERD
논문KCI 등재

Quali-Quantitative Analysis of Flavonoids for Mulberry Leaf and Fruit of ‘Suhyang’

2

조회

0

다운로드

7

인용

0

참고문헌

키워드

주제분류농학

초록

BACKGROUND: Globally, mulberry (Morus sp.) is exploited for feeding leaf to silkworms in order to obtain silk fiber or for animal feedstock production. Also, mulberry fruit is known to a by-product that was produced from mulberry tree after harvesting leaves for silkworm rearing, as a yield and consumption of mulberry fruit was increased, it has been fixing to a newincome crop.Mulberry leaves and fruits are used for the health benefits of human beings. Mulberry contains various bioactive components, such as alkaloids and flavonoids. Mulberry flavonoids are an important part of the diet because of their effects on human nutrition. The flavonoids in mulberry leaf and fruit of ‘Suhyang’(Morus alba L.) were determined. METHODSANDRESULTS: Flavonoids formulberry leaf and fruit of ‘Suhyang’ were analysed using ultrahigh performance liquid chromatography coupled with diode array detection and quadrupole time-of-flight mass spectrometry (UPLC-DAD-QTOF/MS) technique.AnUPLCDAD- QTOF/MS system was used, and identification of mulberry leaves constituentswas carried out on the basis of the complementary information obtained fromLC spectra, MS ions, and MS/MS fragments. The mulberry leaf (16 flavonoids) and fruit (9 flavonoids) were isolated and analyzed from Suhyang using UPLC-DAD-QTOF/MS chromatogram. To the best of our knowledge, Quercetin 3-O-(6''-O-malonyl) glucoside and quercetin 3-O-rutinoside (rutin) was detected on the highest content in leaf and fruit, respectively and further researchwill be devoted to evaluate their biological activity. CONCLUSION:Obtaininginformationabout theconcentration of functionalmaterials inmulberry leaves could contribute to the development and promotion of processed, functional products and offer possible industrial use of ‘Suhyang’, holding promises to enhance the overall profitability of sericulture.

Abstract

BACKGROUND: Globally, mulberry (Morus sp.) is exploited for feeding leaf to silkworms in order to obtain silk fiber or for animal feedstock production. Also, mulberry fruit is known to a by-product that was produced from mulberry tree after harvesting leaves for silkworm rearing, as a yield and consumption of mulberry fruit was increased, it has been fixing to a newincome crop.Mulberry leaves and fruits are used for the health benefits of human beings. Mulberry contains various bioactive components, such as alkaloids and flavonoids. Mulberry flavonoids are an important part of the diet because of their effects on human nutrition. The flavonoids in mulberry leaf and fruit of ‘Suhyang’(Morus alba L.) were determined. METHODSANDRESULTS: Flavonoids formulberry leaf and fruit of ‘Suhyang’ were analysed using ultrahigh performance liquid chromatography coupled with diode array detection and quadrupole time-of-flight mass spectrometry (UPLC-DAD-QTOF/MS) technique.AnUPLCDAD- QTOF/MS system was used, and identification of mulberry leaves constituentswas carried out on the basis of the complementary information obtained fromLC spectra, MS ions, and MS/MS fragments. The mulberry leaf (16 flavonoids) and fruit (9 flavonoids) were isolated and analyzed from Suhyang using UPLC-DAD-QTOF/MS chromatogram. To the best of our knowledge, Quercetin 3-O-(6''-O-malonyl) glucoside and quercetin 3-O-rutinoside (rutin) was detected on the highest content in leaf and fruit, respectively and further researchwill be devoted to evaluate their biological activity. CONCLUSION:Obtaininginformationabout theconcentration of functionalmaterials inmulberry leaves could contribute to the development and promotion of processed, functional products and offer possible industrial use of ‘Suhyang’, holding promises to enhance the overall profitability of sericulture.

참고문헌 (28)

  1. Agarwal, S., "Comparison of genetic transformation in Morus alba L. via different regeneration systems", Plant Cell Reports, 26(2), pp.177~185 (2007)
  2. Bharani, S. E., "Immunomodulatory activity of methanolic extract of Morus alba Linn. (mulberry) leaves", Parkistan Journal of Pharmaceutial Sciences, 23(1), pp.63~68 (2010)
  3. Butkhup, L., "Phenolic composition and antioxidant activity of white mulberry (Morus alba L.) fruits", International Journal of Food Science and Technology, 48, pp.934~940 (2013)
  4. Chai, O. H., "Inhibitory effects of Morus alba on compound 48", 80-induced anaphylactic reactions and anti-chicken gamma globulin IgE- mediated mast cell activation, 2005, pp.28(10), 1852~1858
  5. Chen, P. N., "Mulberry anthocyanins, cyaniding 3-rutinoside and cyaniding 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line", Cancer Letters, 235, pp.248~259 (2006)
  6. Choi, E. M., "Effects of Morus alba leaf extract on the production of nitric oxide, prostaglandin E2 and cytokines in RAW264.7 macrophages", Fitoterapia, 76, pp.608~613 (2005)
  7. 최상원, "뽕나무(Morus alba L.) 부위별 생리활성 측정 및 기능성 물질 분석", 한국식품영양과학회지, 44(6), pp.823~831 (2015), 한국식품영양과학회
  8. Dugo, P., "Characterization of the polyphenolic fraction of Morus alba leaves extracts by HPLC coupled to a hybrid IT-TOF MS system", Journal of Separation Science, 32, pp.3627~3634 (2009)
  9. Enkhmaa B., "Mulberry (M. alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice", Journal of Nutrition, 135, pp.729~734 (2005)
  10. Haminiuk, C. W. I., "Phenolic compounds in fruits-An overview", International Journal of Food Science and Technology, 47(10), pp.2023~2044 (2012)
  11. Hegnauer, R., "Chemotaxonomie der pflanzen, band 6, Dicotyledonae: rafflesiaceae-zygophyllaceae", pp.518~553 (1973), Birkhauser Basel
  12. Kalinova, J., "Distribution of vitamin E, squalene, epicatechin and rutin in common buckwheat plants (Fagopyrum esculentum Moech)", Journal of Agricultural and Food Chemistry, 54, pp.5330~5335 (2006)
  13. Katsube, T., "Antioxidant flavonol glycosides in mulberry (Morus alba L.) leaves isolated based on LDL antioxidant activity", Food Chemistry, 97, pp.25~31 (2006)
  14. Kim, H. W., "Anthocyanin changes in the Korean purple-fleshed sweet potato, Shinzami, as affected by steaming and baking", Food Chemistry, 130, pp.966~972 (2012)
  15. Kim, J. W., "Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversedphase high-performance liquid chromatography", Journal of Chromatography A, 1002, pp.93~99 (2003)
  16. Kim, S. Y., "Antioxidative flavonoids from the leaves of Morus alba", Archival of Pharmacal Research, 22, pp.81~85 (1999)
  17. Kim, T. W., "A study on the antidiabetic effect of mulberry fruits", Korean Journal of Sericultural Science, 38, pp.100~107 (1996)
  18. Pawlowska, A. M., "Quali-quantitative analyses of flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits", Journal of Agricultural and Food Chemistry, 56, pp.3377~3380 (2008)
  19. Ross, J. A., "Dietary flavonoids:bioavailability, metabolic effects, and safety", Annual Review of Nutrition, 22, pp.19~34 (2002)
  20. Singab, A. N., "Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocininduced diabetic rats", Journal of Ethnopharmacology, 100(3), pp.333~338 (2005)
  21. Sung, G. B., "Breeding of early maturing cultivar ‘Suhyang’(Morus alba L.) for mulberry fruit production", Journal of Sericultural and Entomological Science, 52(1), pp.64~72 (2014)
  22. Thabti, I., "Phenols, flavonoids, and antioxidant and antibacterial activity of leaves and stem bark of Morus species", International Journal of Food Properties, 17, pp.842~854 (2014)
  23. Thabti, I., "Identification and quantification of phenolic acids and flavonol glycosides in Tunisian Morus species by HPLC-DAD and HPLC-MS", Journal of Functional Foods, 4, pp.367~374 (2012)
  24. Wang, J., "Isolation of flavonoids from mulberry (Morus alba L.)leaves with macroporous resins", African Journal of Biotechnology, 7, pp.2147~2155 (2008)
  25. Wiczkowski, W., "Food flavonoids", Polish Journal of Food and Nutrition Sciences, 13, pp.101~114 (2004)
  26. Zhang, D., "Ultrasound extraction of polysaccharides from mulberry leaves and their effect on enhancing antioxidant activity", Carbohydrate Polymers, 137, pp.473~479 (2016)
  27. Zhang, W., "HPLC-DADESI-MS", MS analysis and antioxidant activities of nonanthocyanin phenolics in mulberry (Morus alba L.), 2008, pp.73(6), C512~C518
  28. Zhishen J, "The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals", Food Chemistry, 64, pp.555~559 (1999)

관련 논문AI추천

Flavonoids analysis about mulberry fruit of Korean mulberry cultivar, ‘Daeshim’권오철, 김용순, 김종길, 김현복, 성규병, 주완택한국잠사학회 · International Journal of Industrial Entomology and Biomaterials2018 · 제37권 제2호Flavonoids analysis in leaves and fruits of Korean mulberry cultivar, Baekokwang having white fruits이소라, Bonwoo Koo, HaeYong Kweon, Hyun-Bok Kim, SooHyun Kim, Wan-Taek Ju, You-Young Jo한국잠사학회 · International Journal of Industrial Entomology and Biomaterials2020 · 제41권 제2호UPLC-DAD-QTOF/MS를 이용한 대추나무(Zizyphus jujuba var. inermis (Bunge) Rehder) 잎과 열매의 플라보노이드 배당체 분석김숙배, 김영진, 김정봉, 김헌웅, 이민기, 이선혜, 이성현, 장환희, 정현아, 최정숙한국식품저장유통학회 · Food Science and Preservation2016 · 제23권 제7호Characterization of Mulberry Root Bark Extracts (Morus alba L.) Based on the Extraction Temperature and Solvent권해영, 김현복, 주완택, Seong-Wan Kim, Soo Hyun Kim, Sora Lee, You-Young Jo한국잠사학회 · International Journal of Industrial Entomology and Biomaterials2020 · 제41권 제2호Effect of the Nutritive Components of Mulberry Fruits From Two Cultivars Based on Irrigation Scheduling권해용, Heon-Woong Kim, Sora Lee, Wan‐Taek Ju, You‐Young Jo한국환경농학회 · 한국환경농학회지2020 · 제39권 제4호A comparative analysis of characteristics and antioxidant capacity of Korean mulberries for efficient seedling cultivation김기영, 김성렬, 김성완, 김헌웅, 김현복, 박종우, 이지혜, 정찬영, Ik Seob Cha, Sang Kug Kang한국잠사학회 · International Journal of Industrial Entomology and Biomaterials2023 · 제47권 제2호

이 간행물의 다른 논문 (10건)