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歸腎丸이 白鼠의 排卵과 卵巢에 미치는 影響

Effects of Guisinhwan on the Ovulation and Ovary in Rats

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Abstract

Purpose : This study is to examine what are the effects of the Guisinhwan(GSH) on the ovulation and ovary in rats. Methods : 4weeks Female Sprague-Dawley 12 rats of weighting 160-180g, were divided into three groups including the GSH oral administration(4㎖/㎏) groups(4heads) and GSH oral administration(8㎖/㎏) groups(4heads). Then we observed changes in the serum concentrations of FSH, LH, and estradiol(E2) and the histological changes of ovary and the immunohistochemical staining for progesterone receptor in ovary of rats. Results : 1. GSH didn't make a difference as compared with control group in serum FSH level. 2. GSH didn't make a difference as compared with control group in serum LH level. 3. GSH significantly increased serum E2 level. 4. GSH significantly increased ovulation in histological observations of ovary. 5. GSH tended to decrease immunohistochemical staining score (ISS) of atretic follicles in immunohistochemical staining for progesterone receptor in ovary. Conclusion : GSH influences ovary to increase the ovulation of rats.

참고문헌 (42)

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