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최근에 한국인에서 대장암이 증가하는 이유는?

The reasons for the increased incidence of colorectal cancer in Korea

김주성|고성준
대한내과학회 (The Korean Association Of Internal Medicine)|2010.08|대한내과학회지 (The Korean Journal of Medicine)|제79권 제2호|pp. 97-103

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참고문헌

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초록

산업화된 서양 국가에서 발병수준이 높았던 대장암은 일본과 우리나라를 포함한 아시아 국가들에서도 빠른 속도로 증가하고 있다. 이러한 변화는 식이 습관의 변화와 전반적인 신체 활동의 감소 그리고 비만을 포함한 대사증후군의 요인들과 밀접한 관련이 있는 것으로 생각되며 많은 역학 연구 에서 이런 가설을 뒷받침하고 있다. 이는 식이 요인, 신체활동 그리고 비만과 대사증후군의 요인들을 조절하여 대장암 발생의 위험을 감소시킬 수 있다는 의미도 포함한다. 대장암발생이 증가함에 따라 향후 대장암으로 인한 사회-경제적 비용이 현저히 증가할 것으로 예상된다. 따라서 대장암의 일차예방에 대한 관심과 함께 대장암 발생의 증가를 억제하기 위한 적극적인 정책과 노력이 필요한 시점이다.

Abstract

The incidence of colorectal cancer in Korea has increased dramatically over the past few decades. According to the National Cancer Registry, the age-standardized incidence rates increased from 27.1 to 44.5 per 100,000 for men and from 17.2 to 24.3 per 100,000 for women between 1999 and 2007. The overall incidence of colorectal cancer increased by 7.0% annually in men and 5.3% in women from 1999 to 2007, while the incidence rates of the most common cancers, such as stomach and liver cancers, decreased during the same period. Epidemiologic studies have suggested that higher intakes of red and processed meat, a lack of physical activity, obesity, and alcohol drinking are risk factors for colorectal cancer. During the past few decades, significant socio-economic changes have taken place in Korea with respect to the economy, industrial structure, dietary habits, physical activity, and prevalence of obesity. Changes in dietary habits and lifestyle-related factors are believed to be the reasons for the increase in the incidence of colorectal cancer in Korea.

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