A Proposal for a Predictive Model for the Number of Patients with Periodontitis Exposed to Particulate Matter and Atmospheric Factors Using Deep Learning
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background: Particulate matter (PM) has been extensively observed due to its negative association with human health. Previous research revealed the possible negative effect of air pollutant exposure on oral health. However, the predictive model between air pollutant exposure and the prevalence of periodontitis has not been observed yet. Therefore, this study aims to propose a predictive model for the number of patients with periodontitis exposed to PM and atmospheric factors in South Korea using deep learning.Methods: This study is a retrospective cohort study utilizing secondary data from the Korean Statistical Information Service and the Health Insurance Review and Assessment database for air pollution and the number of patients with periodontitis, respectively. Data from 2015 to 2022 were collected and consolidated every month, organized by region. Following data matching and management, the deep neural networks (DNN) model was applied, and the mean absolute percentage error (MAPE) value was calculated to ensure the accuracy of the model. Results: As we evaluated the DNN model with MAPE, the multivariate model of air pollution including exposure to PM2.5, PM10, and other atmospheric factors predict approximately 85% of the number of patients with periodontitis. The MAPE value ranged from 12.85 to 17.10 (mean±standard deviation=14.12±1.30), indicating a commendable level of accuracy. Conclusion: In this study, the predictive model for the number of patients with periodontitis is developed based on air pollution, including exposure to PM2.5, PM10, and other atmospheric factors. Additionally, various relevant factors are incorporated into the developed predictive model to elucidate specific causal relationships. It is anticipated that future research will lead to the development of a more accurate model for predicting the number of patients with periodontitis.
Abstract
Background: Particulate matter (PM) has been extensively observed due to its negative association with human health. Previous research revealed the possible negative effect of air pollutant exposure on oral health. However, the predictive model between air pollutant exposure and the prevalence of periodontitis has not been observed yet. Therefore, this study aims to propose a predictive model for the number of patients with periodontitis exposed to PM and atmospheric factors in South Korea using deep learning.Methods: This study is a retrospective cohort study utilizing secondary data from the Korean Statistical Information Service and the Health Insurance Review and Assessment database for air pollution and the number of patients with periodontitis, respectively. Data from 2015 to 2022 were collected and consolidated every month, organized by region. Following data matching and management, the deep neural networks (DNN) model was applied, and the mean absolute percentage error (MAPE) value was calculated to ensure the accuracy of the model. Results: As we evaluated the DNN model with MAPE, the multivariate model of air pollution including exposure to PM2.5, PM10, and other atmospheric factors predict approximately 85% of the number of patients with periodontitis. The MAPE value ranged from 12.85 to 17.10 (mean±standard deviation=14.12±1.30), indicating a commendable level of accuracy. Conclusion: In this study, the predictive model for the number of patients with periodontitis is developed based on air pollution, including exposure to PM2.5, PM10, and other atmospheric factors. Additionally, various relevant factors are incorporated into the developed predictive model to elucidate specific causal relationships. It is anticipated that future research will lead to the development of a more accurate model for predicting the number of patients with periodontitis.
참고문헌 (30)
- Liu Y, "Trends in all causes and cause specific mortality attributable to ambient particulate matter pollution in China from 1990 to 2019 : a secondary data analysis study", PLoS One, 18, pp.e0291262~ (2023)[DOI]
- He L, "Oral cavity response to air pollutant exposure and association with pulmonary inflammation and symptoms in asthmatic children", Environ Res, 206, pp.112275~ (2022)[DOI]
- Rajkumar RP, "The relationship between ambient fine particulate matter(PM2. 5)pollution and depression : an analysis of data from 185 countries", Atmosphere, 14, pp.597~ (2023)[DOI]
- Lee DU, "Dust particles-induced intracellular Ca2+ signaling and reactive oxygen species in lung fibroblast cell line MRC5", Korean J Physiol Pharmacol, 21, pp.327~334 (2017)[DOI]
- Kim KH, "A review on the human health impact of airborne particulate matter", Environ Int, 74, pp.136~143 (2015)[DOI]
- Li Y, "Ambient temperature enhanced acute cardiovascular-respiratory mortality effects of PM2. 5in Beijing, China", Int J Biometeorol, 59, pp.1761~1770 (2015)[DOI]
- Orellano P, "Short-term exposure to sulphur dioxide(SO2)and all-cause and respiratory mortality : a systematic review and meta-analysis", Environ Int, 150, pp.106434~ (2021)[DOI]
- Chen RJ, "Carbon monoxidetriggered health effects : the important role of the inflammasome and its possible crosstalk with autophagy and exosomes", Arch Toxicol, 95, pp.1141~1159 (2021)[DOI]
- Meng X, "Short term associations of ambient nitrogen dioxide with daily total, cardiovascular, and respiratory mortality : multilocation analysis in 398 cities", BMJ, 372, pp.n534~ (2021)[DOI]
- Holm SM, "Systematic review of ozone effects on human lung function, 2013 through 2020", Chest, 161, pp.190~201 (2022)[DOI]
- Vo TTT, "Potential effects of noxious chemical-containing fine particulate matter on oral health through reactive oxygen species-mediated oxidative stress : promising clues", Biochem Pharmacol, 182, pp.114286~ (2020)[DOI]
- Marruganti C, "Air pollution as a risk indicator for periodontitis", Biomedicines, 11, pp.443~ (2023)[DOI]
- Lin HJ, "Prolonged exposure to air pollution increases periodontal disease risk : a nationwide, population-based, cohort study", Atmosphere, 12, pp.1668~ (2021)[DOI]
- Xiong K, "Research on the association between periodontitis and COPD", Int J Chron Obstruct Pulmon Dis, 18, pp.1937~1948 (2023)[DOI]
- Slots J, "Periodontitis : facts, fallacies and the future", Periodontol 2000, 75, pp.7~23 (2017)[DOI]
- Larsson L, "Current concepts of epigenetics and its role in periodontitis", Curr Oral Health Rep, 4, pp.286~293 (2017)[DOI]
- LeCun Y, "Deep learning", Nature, 521, pp.436~444 (2015)[DOI]
- Kim OJ, "Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0. 2 million adults", Environ Health, 19, pp.113~ (2020)[DOI]
- Hwang J, "Impact of air pollution on breast cancer incidence and mortality : a nationwide analysis in South Korea", Sci Rep, 10, pp.5392~ (2020)[DOI]
- Oh HR, "Impact of Chinese air pollutants on a record-breaking PMs episode in the Republic of Korea for 11–15 January 2019", Atmos Environ, 223, pp.117262~ (2020)[DOI]
- Min KD, "Association between exposure to traffic-related air pollution and pediatric allergic diseases based on modeled air pollution concentrations and traffic measures in Seoul, Korea : a comparative analysis", Environ Health, 19, pp.6~ (2020)[DOI]
- Lewis CD, "Industrial and business forecasting methods: a practical guide to exponential smoothing and curve fitting" (1982), Butterworth Scientific
- Yang TH, "Personal exposure to particulate matter and inflammation among patients with periodontal disease", Sci Total Environ, 502, pp.585~589 (2015)[DOI]
- Huang K, "The modification of meteorological factors on the relationship between air pollution and periodontal diseases : an exploration based on different interaction strategies", Environ Geochem Health, 45, pp.8187~8202 (2023)[DOI]
- Seo JH, "Changes in air quality during the COVID-19 pandemic and associated health benefits in Korea", Appl Sci, 10, pp.8720~ (2020)[DOI]
- Seo JH, "Impact of the COVID-19 outbreak on air quality in Korea", Atmosphere, 11, pp.1137~ (2020)[DOI]
- Kyung SY, "Particulate-matter related respiratory diseases", Tuberc Respir Dis (Seoul), 83, pp.116~121 (2020)[DOI]
- D'Ercole S, "Correlation between use of different type protective facemasks and the oral ecosystem", BMC Public Health, 23, pp.1992~ (2023)[DOI]
- Hung M, "Application of machine learning for diagnostic prediction of root caries", Gerodontology, 36, pp.395~404 (2019)[DOI]
- Kang IA, "DCP : prediction of dental caries using machine learning in personalized medicine", Appl Sci, 12, pp.3043~ (2022)[DOI]
