본문 바로가기
KERD
논문KCI 등재

전북지역 염소에서 Coxiella burnetii 감염실태 조사

Prevalence of Coxiella burnetii in native Korean goat in Jeonbuk province

1

조회

0

다운로드

5

인용

0

참고문헌

키워드

주제분류수의학

초록

The prevalence of Coxiella burnetii in native Korean goats in Jeonbuk province was investigated using ELISA (sera) and PCR (vaginal mucus). A total of 798 blood samples from 189 farms were collected in 2013 and 2015. Seroprevalence was 13.6% in 2013 and 15.7% in 2015. Tracking survey of six sero-positive farms on the prevalence of C. burnetii was conducted. 137 (41.4%) out of 331 goats were sero-positive and 47 (17.6%) out of 267 goats were positive in PCR. The higher seropositivity observed in adult goats and female goats significantly, the seroprevalence of C. burnetii was higher as age increased (<1 y=13.2%∼≥5 y=100%)(P<0.05) and female goats (44.8%) was higher than male goats (24.1%) on the seroprevalence (P<0.05). 21 (7.9%) goats positive in PCR was seronegative. The prevalence of C. burnetii in native Korean goats in slaughter house was 30.0% in ELISA and 11.5% in PCR. Signi-ficantly, female goats (62.8%) was higher than male goats (12.3%) on the seroprevalence (P<0.05). Based on these data, C. burnetii was easily exposed in domestic animals: native Korean goats-related areas such as farms and slaughter house.

Abstract

The prevalence of Coxiella burnetii in native Korean goats in Jeonbuk province was investigated using ELISA (sera) and PCR (vaginal mucus). A total of 798 blood samples from 189 farms were collected in 2013 and 2015. Seroprevalence was 13.6% in 2013 and 15.7% in 2015. Tracking survey of six sero-positive farms on the prevalence of C. burnetii was conducted. 137 (41.4%) out of 331 goats were sero-positive and 47 (17.6%) out of 267 goats were positive in PCR. The higher seropositivity observed in adult goats and female goats significantly, the seroprevalence of C. burnetii was higher as age increased (<1 y=13.2%∼≥5 y=100%)(P<0.05) and female goats (44.8%) was higher than male goats (24.1%) on the seroprevalence (P<0.05). 21 (7.9%) goats positive in PCR was seronegative. The prevalence of C. burnetii in native Korean goats in slaughter house was 30.0% in ELISA and 11.5% in PCR. Signi-ficantly, female goats (62.8%) was higher than male goats (12.3%) on the seroprevalence (P<0.05). Based on these data, C. burnetii was easily exposed in domestic animals: native Korean goats-related areas such as farms and slaughter house.

참고문헌 (43)

  1. Angelakis E, "Q fever", Vet Microbiol, 140, pp.297~309 (2010)
  2. Arricau-Bouvery N, "Effect of vaccination with phase I and phase II Coxiella burnetii vaccines in pregnant goats", Vaccine, 23, pp.4392~4402 (2005)
  3. Astobiza I, "Evaluation of the efficacy of oxytetracycline treatment followed by vaccination against Q fever in a highly infected sheep flock", Vet J, 196, pp.81~85 (2013)
  4. Berri M, "The detection of Coxiella burnetii from ovine genital swabs, milk and fecal samples by the use of a single touchdown polymerase chain reaction", Vet Microbiol, 72, pp.285~293 (2000)
  5. Bossi P, "Bichat Guidelines for the clinical management of Q fever and Bioterrorism-related Q fever", Surveill, 9, pp.12~ (2004)
  6. Centers for Disease Control & Prevention, "A Survey on the Status of Zoonoses among Veterinarians Related to Public Professional Activities, 2014", PHWR, 8, pp.262~263 (2015)
  7. Derrick EH, "“Q” fever, a new fever entity: clinical features, diagnosis and laboratory investigation", Med J Aust, 2, pp.281~299 (1937)
  8. Dijkstra F, "The 2007–2010 Q fever epidemic in The Netherlands: character istics of notified acute Q fever patients and the association with dairy goat farming", FEMS Immunol Med Microbiol, 64, pp.3~12 (2012)
  9. Eibach R, "Q fever: baseline monitoring of a sheep and a goat flock associated with human infections R", Epidemiol Infect, 140, pp.1939~1949 (2012)
  10. Guatteo R, "Shedding and serological patterns of dairy cows following abortions associated with Coxiella burnetii DNA detection", Vet Microbiol, 155, pp.430~433 (2012)
  11. Hawker JI, "A large outbreak of Q fever in the West Midlands: windborne spread into a metropolitan area", Commun Dis Public Health, 1, pp.180~187 (1998)
  12. Htwe KK, "Seroepidemiology of Coxiella burnetii in domestic and companion animals", Vet Rec, 131, pp.490~ (1992)
  13. Jo NI, "Serological study on Q fever by detection of complement fixation antibodies to Coxiella burnetii in dairy cattle in Kyunggi province", Kor J Env Hlth, 20, pp.19~30 (1994)
  14. Jung BY, "Molecular and serologic detection of Coxiella burnetii in native Korean goats (Capra hircus coreanae)", Vet Microbiol, 173, pp.152~155 (2014)
  15. Kazar J, "Coxiella burnetii infection", Ann N Y Acad Sci, 1063, pp.105~114 (2005)
  16. Khalili M, "An update on a serologic survey of Q Fever in domestic animals in Iran", Am J Trop Med Hyg, 80, pp.1031~1032 (2009)
  17. 김지연, "국내 서식 한우에서 큐열 항체 양성율 조사", 대한수의학회지, 54(3), pp.147~150 (2014), 대한수의학회[DOI]
  18. 김능희, "서울지역 사육 소의 큐열 및 톡소포자충 항체 보유율 조사", 한국가축위생학회지, 38(4), pp.233~239 (2015), 한국가축위생학회
  19. 김성국, "경북지역 재래염소의 Coxiella burnetii 항체보유율", 한국가축위생학회지, 37(4), pp.241~246 (2014), 한국가축위생학회
  20. Woo Jin Kim, "Seroprevalence of Coxiella burnetii Infection in Dairy Cattle and Non-symptomatic People for Routine Health Screening in Korea", Journal of Korean Medical Science, 21(5), pp.823~826 (2006), 대한의학회
  21. Lee MH, "A Case of Q fever arising in the Patient with Cervical Carcinoma", Obstetrics Gynecol Sci, pp.2478~2482 (1994)
  22. Marrie TJ, "Mandell, Douglas and Bennett’s principles and practice of infectious diseases", pp.2043~2050 (2000), Churchill Livingstone
  23. Maurin M, "Q fever", Clin Microbiol Rev, 12, pp.518~553 (1999)
  24. McQuiston JH, "Q fever in humans and animals in the United States", Vector Borne Zoonotic Dis, 2, pp.179~191 (2002)
  25. Muskens J, "Prevalence of Coxiella burnetii infection in Dutch dairy herds based on testing bulk tank milk and individual samples by PCR and ELISA", Vet Rec, 168, pp.79~ (2011)
  26. Muskens J, "Prevalence of Coxiella burnetii infections in aborted fetuses and stillborn calves", Vet Rec, 170, pp.260~ (2012)
  27. 우인옥, "경북지역 집합유와 젖소에서 큐열 항체 보유율 조사", 한국가축위생학회지, 36(4), pp.243~248 (2013), 한국가축위생학회
  28. Oyston PC, "Q fever : the neglected biothreat agent", J Med Microbiol, 60, pp.9~21 (2011)
  29. 박만석, "원인불명 발열성 및 비정형성 폐렴 환자의 Coxiella burnetii 항체 분포 특성", Journal of Bacteriology and Virology, 33(4), pp.307~315 (2003), 대한미생물학회
  30. Porter SR, "Q fever in Japan: An update review", Vet Microbiol, 149, pp.298~306 (2011)
  31. Psaroulaki A, "Epidemiological study of Q fever in humans, ruminant animals, and ticks in Cyprus using a geographical information system", Eur J Clin Microbiol Infect Dis, 25, pp.576~586 (2006)
  32. Raoult D, "Q fever: still a query after all these years", J Med Microbiol, 44, pp.77~78 (1996)
  33. Rodolakis A, "Comparison of Coxiella burnetii shedding in milk of dairy bovine, caprine and ovine herds", J Dairy Sci, 90, pp.55352~55360 (2007)
  34. Roest HIJ, "Molecular epidemiology of Coxiella burnetii from ruminants in Q fever outbreak, the Netherlands", Emerg Infect Dis, 17, pp.668~676 (2011)
  35. Roest HIJ, "The Q fever epidemic in The Netherlands: history, onset, response and reflection", Epidemiol Infect, 139, pp.1~12 (2011)
  36. Rousset, E, "Efficiency of a phase 1 vaccine for the reduction of vaginal Coxiella burnetii shedding in a clinically affected goat herd", Clin Microbiol Infect, 15, pp.188~189 (2009)
  37. Shin GW, "The prevalence of Coxiella burnetii infection in wild Korean water deer, Korea", J Vet Med Sci, 76, pp.1069~1071 (2014)
  38. Sin YJ, "A case of Q fever", Korean J Med, 42, pp.690~698 (1992)
  39. "Korean statistical information service" (2015)[URL]
  40. Szymańska-Czerwińska M, "Evaluation of the Effectiveness of Q Fever Treatment with Oxytetracycline", Bull Vet Inst Pulawy, 56, pp.513~517 (2012)
  41. Tissot-Dupont H, "Hyperendemic focus of Q fever related to sheep and wind", Am J Epidemiol, 150, pp.67~74 (1999)
  42. Vaidya VM, "Comparison of PCR, Immuno fluorescence Assay, and Pathogen Isolation for Diagnosis of Q Fever in Humans with Spontaneous Abortions", J Clinl Microbiol, 46, pp.2038~2044 (2008)

관련 논문AI추천

이 간행물의 다른 논문 (9건)