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EGFR-mutated pulmonary adenocarcinoma with concurrent PIK3CA mutation, and with acquired RET fusion and EGFR T790M mutation after afatinib therapy

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주제분류병리학

참고문헌 (6)

  1. Zhu VW, "Receptor tyrosine kinase fusions as an actionable resistance mechanism to EGFR TKIs in EGFR-mutant non-small-cell lung cancer", Trends Cancer, 5, pp.677~692 (2019)
  2. Eng J, "Impact of concurrent PIK3CA mutations on response to EGFR tyrosine kinase inhibition in EGFRmutant lung cancers and on prognosis in oncogene-driven lung adenocarcinomas", J Thorac Oncol, 10, pp.1713~1719 (2015)
  3. Wang L, "PIK3CA mutations frequently coexist with EGFR", KRAS mutations in non-small cell lung cancer and sug- gest poor prognosis in EGFR, PLoS One, pp.2014, 9[DOI]
  4. Piotrowska Z, "Landscape of acquired resistance to osimertinib in EGFR-mutant NSCLC and clinical validation of combined EGFR and RET inhibition with osimertinib and BLU-667 for acquired RET fusion", Cancer Discov, 8, pp.1529~1539 (2018)
  5. Scheffler M, "PIK3CA mutations in nonsmall cell lung cancer(NSCLC) : genetic heterogeneity, prognostic impact and incidence of prior malignancies", Oncotarget, 6, pp.1315~1326 (2015)
  6. Ahn JW, "Identification of somatic mutations in EGFR", KRAS, Genome Med, pp.2014, 6[DOI]

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