Temporal Volume Change of Cavernous Sinus Cavernous Hemangiomas after Gamma Knife Surgery
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초록
Cavernous hemangiomas occur very rarely in the cavernous sinus. This study aimed to evaluate the efficacy of Gamma Knife surgery(GKS) on cavernous sinus cavernous hemangioma (CSCH) and to analyze the temporal volume change. We retrospectivelyreviewed the clinical data of 26 CSCH patients who were treated with GKS between 2001 and 2017. Before GKS, 11 patients(42.3%) had cranial neuropathies and 5 patients (19.2%) complained of headache, whereas 10 patients (38.5%) were initially asymptomatic. The mean pre-GKS mass volume was 9.3 mL (range, 0.5–31.6 mL), and the margin dose ranged from 13 to 15 Gy accordingto the mass volume and the proximity to the optic pathway. All cranial neuropathy patients and half of headache patientsshowed clinical improvement. All 26 patients achieved mass control; remarkable responses (less than 1/3 of the initial mass volume)were shown in 19 patients (73.1%) and moderate responses (more than 1/3 and less than 2/3) in 7 patients (26.9%). Themean final mass volume after GKS was 1.8 mL (range, 0–12.6 mL). The mean mass volume at 6 months after GKS was 45% (range,5–80%) compared to the mass volume before GKS and 21% (range, 0–70%) at 12 months. The higher radiation dose tended to inducemore rapid and greater volume reduction. No treatment-related complication was observed during the follow-up period. GKS could be an effective and safe therapeutic strategy for CSCH. GKS induced very rapid volume reduction compared to otherbenign brain tumors.
Abstract
Cavernous hemangiomas occur very rarely in the cavernous sinus. This study aimed to evaluate the efficacy of Gamma Knife surgery(GKS) on cavernous sinus cavernous hemangioma (CSCH) and to analyze the temporal volume change. We retrospectivelyreviewed the clinical data of 26 CSCH patients who were treated with GKS between 2001 and 2017. Before GKS, 11 patients(42.3%) had cranial neuropathies and 5 patients (19.2%) complained of headache, whereas 10 patients (38.5%) were initially asymptomatic. The mean pre-GKS mass volume was 9.3 mL (range, 0.5–31.6 mL), and the margin dose ranged from 13 to 15 Gy accordingto the mass volume and the proximity to the optic pathway. All cranial neuropathy patients and half of headache patientsshowed clinical improvement. All 26 patients achieved mass control; remarkable responses (less than 1/3 of the initial mass volume)were shown in 19 patients (73.1%) and moderate responses (more than 1/3 and less than 2/3) in 7 patients (26.9%). Themean final mass volume after GKS was 1.8 mL (range, 0–12.6 mL). The mean mass volume at 6 months after GKS was 45% (range,5–80%) compared to the mass volume before GKS and 21% (range, 0–70%) at 12 months. The higher radiation dose tended to inducemore rapid and greater volume reduction. No treatment-related complication was observed during the follow-up period. GKS could be an effective and safe therapeutic strategy for CSCH. GKS induced very rapid volume reduction compared to otherbenign brain tumors.
참고문헌 (22)
- Gonzalez LF, "Are cavernous sinus hemangiomas and cavernous malformations different entities", Neurosurg Focus, 21, pp.e6~ (2006)
- Zhou LF, "Diagnosis and surgical treatment of cavernous sinus hemangiomas : an experience of 20 cases", Surg Neurol, 60, pp.31~36 (2003)
- Linskey ME, "Cavernous sinus hemangiomas : a series, a review, and an hypothesis", Neurosurgery, 30, pp.101~108 (1992)
- Li P, "Clinical results of Gamma Knife surgery for cavernous sinus hemangiomas", J Neurosurg (2012)
- Dou Y, "Diagnosis and microsurgical treatment of cavernous sinus hemangioma", Artif Cells Blood Substit Immobil Biotechnol, 38, pp.109~112 (2010)
- Salanitri GC, "Extracerebral cavernous hemangioma of the cavernous sinus : diagnosis with MR imaging and labeled red cell blood pool scintigraphy", AJNR Am J Neuroradiol, 25, pp.280~284 (2004)
- Polito E, "Technetium tc 99m-labeled red blood cells in the preoperative diagnosis of cavernous hemangioma and other vascular orbital tumors", Arch Ophthalmol, 123, pp.1678~1683 (2005)
- Shi J, "Cavernous hemangiomas in the cavernous sinus", Neurosurgery, 45, pp.1308~1313 (1999)
- Ohata K, "Efficacy of induced hypotension in the surgical treatment of large cavernous sinus cavernomas", J Neurosurg, 90, pp.702~708 (1999)
- Bansal S, "Cavernous sinus hemangioma : a fourteen year single institution experience", J Clin Neurosci, 21, pp.968~974 (2014)
- Goel A, "The extradural approach to lesions involving the cavernous sinus", Br J Neurosurg, 11, pp.134~138 (1997)
- Suri A, "Extradural transcavernous approach to cavernous sinus hemangiomas", Neurosurgery, 60, pp.483~488 (2007)
- Shibata S, "Effect of radiation therapy on extracerebral cavernous hemangioma in the middle fossa. Report of three cases", J Neurosurg, 67, pp.919~922 (1987)
- Rigamonti D, "Extracerebral cavernous angiomas of the middle fossa", Neurosurgery, 27, pp.306~310 (1990)
- Maruishi M, "Cavernous sinus cavernoma treated with radiation therapy--case report", Neurol Med Chir(Tokyo), 34, pp.773~777 (1994)
- Iwai Y, "Stereotactic radiosurgery for cavernous sinus cavernous hemangioma", Neurol Med Chir(Tokyo), 39, pp.288~290 (1999)
- Chou CW, "Gamma knife surgery for cavernous hemangiomas in the cavernous sinus", Neurosurgery, 67, pp.611~616 (2010)
- Yamamoto M, "Gamma Knife radiosurgery for hemangiomas of the cavernous sinus : a seven-institute study in Japan", J Neurosurg, 112, pp.772~779 (2010)
- Thompson TP, "Radiosurgery for hemangiomas of the cavernous sinus and orbit : technical case report", Neurosurgery, 47, pp.778~783 (2000)
- Peker S, "Radiosurgical treatment of cavernous sinus cavernous haemangiomas", Acta Neurochir(Wien), 146, pp.337~341 (2004)
- Khan AA, "Stereotactic radiosurgery for cavernous sinus or orbital hemangiomas", Neurosurgery, 65, pp.914~918 (2009)
- Wang X, "The role of stereotactic radiosurgery in cavernous sinus hemangiomas : a systematic review and meta-analysis", J Neurooncol, 107, pp.239~245 (2012)