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Choice of Thresholding Technique in Micro-CT Images of Trabecular Bone Does Not Influence the Prediction of Bone Volume Fraction and Apparent Modulus

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Abstract

Trabecular bone can be accurately represented using image-based finite element modeling and analysis of these bone models is widely used to predict their mechanical properties. However, the choice of thresholding technique, a necessary step in converting grayscale images to finite element models which can thus significantly influence the structure of the resulting finite element model, is often overlooked. Therefore, we investigated the effects of thresholding techniques on micro-computed tomography (micro-CT) based finite element models of trabecular bone. Three types of thresholding techniques were applied to micro-CT images of trabecular bone which resulted in three unique finite element models for each specimen. Bone volume fractions and apparent moduli were predicted for each model and compared to experimental results. Our findings suggest that predictions of apparent properties agree well with experimental measurements regardless of the choice of thresholding technique in micro CT images of trabecular bone.

참고문헌 (22)

  1. S. Majumdar, "Assessment of trabecular structure using high resolution magnetic resonance imaging", 40, pp.81~96 (1997)
  2. S. Majumdar, "Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status: in vivo studies in the distal radius using high resolution magnetic resonance imaging", 12, pp.111~118 (1997)
  3. J.L. Kuhn, "Evaluation of a microcomputed tomography system to study trabecular bone structure", 8, pp.833~842 (1990)
  4. P. Ruegsegger, "A microtomographic system for the nondestructive evaluation of bone architecture", 58, pp.24~29 (1996)
  5. J.A. Hipp, "Trabecular bone morphology from micro-magnetic resonance imaging", 11, pp.286~297 (1996)
  6. B. van Rietbergen, "Assessment of cancellous bone mechanical properties from micro-FE models based on micro-CT, pQCT and MR images", 6, pp.413~420 (1998)
  7. B. Van Rietbergen, "Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions", 32, pp.165~173 (1999)
  8. J.P. van den Bergh, "Speed of sound reflects Young's modulus as assessed by microstructural finite element analysis", 26, pp.519~524 (2000)
  9. G.L. Niebur, "High-resolution finite element models with tissue strength asymmetry accurately predict failure of trabecular bone", 33, pp.1575~1583 (2000)
  10. G.L. Niebur, "Sensitivity of damage predictions to tissue level yield properties and apparent loading conditions", 34, pp.699~706 (2001)
  11. G.L. Niebur, "Conve- rgence behavior of high-resolution finite element models of trabecular bone", 121, pp.629~635 (1999)
  12. B. Borah, "Three-dimensional microimaging (MRmicroI and microCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis", 265, pp.101~110 (2001)
  13. G.T. Charras, "Improving the local solution accuracy of large-scale digital image-based finite element analyses", 33, pp.255~259 (2000)
  14. D. Ulrich, "The quality of trabecular bone evaluated with micro-computed tomography, FEA and mechanical testing", 40, pp.97~112 (1997)
  15. D. Ulrich, "Finite element analysis of trabecular bone structure: a comparison of image-based meshing techniques", 31, pp.1187~1192 (1998)
  16. R.E. Guldberg, "The accuracy of digital image-based finite element models", 120, pp.289~295 (1998)
  17. A.J. Ladd, "Finite-element modeling of trabecular bone: comparison with mechanical testing and determination of tissue modulus", 16, pp.622~628 (1998)
  18. J. Homminga, "Introduction and evaluation of a gray-value voxel conversion technique", 34, pp.513~517 (2001)
  19. T. Hara, "The influence of microcomputed tomography threshold variations on the assessment of structural and mechanical trabecular bone properties", 31, pp.107~109 (2002)
  20. T.M. Keaveny, "Trabecular bone exhibits fully linear elastic behavior and yields at low strains", 27, pp.1127~1136 (1994)
  21. S.J. Hollister, "A homogenization sampling procedure for calculating trabecular bone effective stiffness and tissue level stress", 27, pp.433~444 (1994)
  22. X.E. Guo, "Is trabecular bone tissue different from cortical bone tissue?", 12, pp.185~196 (1997)

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