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비부비동에 발생한 NK/T 세포 림프종의 예후인자 분석

Prognostic Factors of Nasal NK/T Cell Lymphoma

강성욱|홍성표|김현준|강희선|박정섭|윤주헌|김동현
대한이비인후과학회 (Korean Society of Otorhinolaryngology-Head and Neck Surgery)|2007.01|대한이비인후과학회지 두경부외과학 (Korean Journal of Otorhinolaryngology-Head and Neck Surgery)|제50권 제1호|pp. 37-42

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참고문헌

키워드

NK/T 세포 림프종·예후인자·International prognostic index.Nasal NK/T cell lymphoma· Prognostic factor· International prognostic index.
주제분류이비인후과학

초록

Abstract

Background and Objectives：Nasal natural killer T (NK/T) cell lymphomas are relatively comon in Asia, but the prognostic factors are not wel known. The purpose of this research was therefore to evaluate those prognostic factors. Subjects and Method：We reviewed and analyzed the medical records of 68 patients diagnosed as nasal NK/T cell lymphomas between 1984 lactate dehydrogenase (LDH) levels, Eastern cooperative oncology group (ECOG) performance status, international prognostic indices (IPI), treatment modality, and Ann Arbor tumor stages were analyzed using the methods of univariate and multivariate statistics. Results：The five-year overall survival rate was 43%. By univariate analysis, we found ECOG performance status, Ann Arbor tumor stages, B symptoms, and IPI to be significant prognostic factors of nasal NK/T cell lymphoma. The multivariate Conclusion：ECOG performance status, Ann Arbor tumor stages, B symptoms, and IPI could all be prognostic factors of the nasal NK/T cell lymphoma. Among these factors, ECOG performance status and B symptoms may be regarded more useful in diagnosis of the disease than others. (Korean J Otolaryngol 2007 ;50 :37-42)

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