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Applicability of the digital instrument to improve the reproducibility of motor unit number index

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Background: The motor unit number index (MUNIX) and motor unit size index (MUSIX) refer to the electrophysiological measurement of the motor units using the surface electromyographic interference pattern (SIP) recorded during graded muscle contraction. In order to improve the reliability and reproducibility of MUNIX by the systematization of the graded muscle contractions, we applied a digital hand instrument to the procedure of recording SIP signals. Methods: We tested the applicability of the digital instrument in the MUNIX technique by assessing the mean values and the reproducibility of the MUNIX involving the abductor pollicis brevis (APB) and the abductor digiti minimi (ADM) muscles in 30 healthy adults. Results: The digital dynamometer was successfully applied to the MUNIX measurements of the APB and ADM muscles, and showed high reproducibility across trials. Conclusions: Application of the digital instrument would be useful in improving the reliability and reproducibility of MUNIX.

Abstract

Background: The motor unit number index (MUNIX) and motor unit size index (MUSIX) refer to the electrophysiological measurement of the motor units using the surface electromyographic interference pattern (SIP) recorded during graded muscle contraction. In order to improve the reliability and reproducibility of MUNIX by the systematization of the graded muscle contractions, we applied a digital hand instrument to the procedure of recording SIP signals. Methods: We tested the applicability of the digital instrument in the MUNIX technique by assessing the mean values and the reproducibility of the MUNIX involving the abductor pollicis brevis (APB) and the abductor digiti minimi (ADM) muscles in 30 healthy adults. Results: The digital dynamometer was successfully applied to the MUNIX measurements of the APB and ADM muscles, and showed high reproducibility across trials. Conclusions: Application of the digital instrument would be useful in improving the reliability and reproducibility of MUNIX.

참고문헌 (11)

  1. Nandedkar SD, "Motor unit number index (MUNIX)", IEEE Trans Biomed Eng, 51, pp.2209~2211 (2004)[DOI]
  2. Ahn SW, "Reproducibility of the motor unit number index (MUNIX) in normal controls and amyotrophic lateral sclerosis patients", Muscle Nerve, 42, pp.808~813 (2010)[DOI]
  3. Nandedkar SD, "Motor unit number index (MUNIX): principle, method, and findings in healthy subjects and in patients with motor neuron disease", Muscle Nerve, 42, pp.798~807 (2010)[DOI]
  4. Neuwirth C, "Motor Unit Number Index (MUNIX): reference values of five different muscles in healthy subjects from a multi-centre study", Clin Neurophysiol, 122, pp.1895~1898 (2011)[DOI]
  5. Nandedkar SD, "Reproducibility of MUNIX in patients with amyotrophic lateral sclerosis", Muscle Nerve, 44, pp.919~922 (2011)[DOI]
  6. Ahn SW, "Motor unit number index (MUNIX) in the orbicularis oculi muscle of healthy subjects", Muscle Nerve, 51, pp.197~200 (2015)[DOI]
  7. Bromberg MB, "Motor unit estimation: reproducibility of the spike-triggered averaging technique in normal and ALS subjects", Muscle Nerve, 16, pp.466~471 (1993)[DOI]
  8. Felice KJ, "Thenar motor unit number estimates using the multiple point stimulation technique: reproducibility studies in ALS patients and normal subjects", Muscle Nerve, 18, pp.1412~1416 (1995)[DOI]
  9. Lomen-Hoerth C, "Comparison of multiple point and statistical motor unit number estimation", Muscle Nerve, 23, pp.1525~1533 (2000)[DOI]
  10. Simmons Z, "Reproducibility of motor unit number estimation in individual subjects", Muscle Nerve, 24, pp.467~473 (2001)[DOI]
  11. Olney RK, "Statistical motor unit number estimation: reproducibility and sources of error in patients with amyotrophic lateral sclerosis", Muscle Nerve, 23, pp.193~197 (2000)[DOI]

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