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Analysis of Risk Factors to Predict Occurrence and Prognosis of Postsurgical Hypertrophic Scar Development: A Review of 4238 Cases

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초록

Purpose: This study aimed to identify the risk factors associated with the occurrence and prognosis of hypertrophic scarring fol lowing thyroidectomy. Materials and Methods: A total of 4238 patients who underwent thyroidectomy were included in this study. A multivariable lo gistic regression model was developed to identify the risk factors for hypertrophic scar development and its prognosis. Results: Our analysis revealed that hypertrophic scar development was associated with younger age [odds ratio (OR)=0.949, p<0.0001], male sex (OR=0.562, p<0.0001), higher body mass index (OR=1.137, p<0.0001), prominent sternocleidomastoid mus cles (OR=2.522, p<0.0001), scarring located within 1 cm of the sternal notch (OR=4.345, p<0.0001), and a history of keloid devel opment (OR=2.789, p=0.0031). Additionally, scar location within 1 cm of the sternal notch (beta=4.326, p=0.0429) and a history of keloid development (beta=23.082, p<0.0001) were found to be associated with the prognosis of hypertrophic scarring. Conclusion: The findings of this study provide valuable insights into the risk factors associated with hypertrophic scarring following thyroidectomy. Clinicians can use this information to predict the occurrence of hypertrophic scarring and its prognosis, and take preventative measures accordingly.

Abstract

Purpose: This study aimed to identify the risk factors associated with the occurrence and prognosis of hypertrophic scarring fol lowing thyroidectomy. Materials and Methods: A total of 4238 patients who underwent thyroidectomy were included in this study. A multivariable lo gistic regression model was developed to identify the risk factors for hypertrophic scar development and its prognosis. Results: Our analysis revealed that hypertrophic scar development was associated with younger age [odds ratio (OR)=0.949, p<0.0001], male sex (OR=0.562, p<0.0001), higher body mass index (OR=1.137, p<0.0001), prominent sternocleidomastoid mus cles (OR=2.522, p<0.0001), scarring located within 1 cm of the sternal notch (OR=4.345, p<0.0001), and a history of keloid devel opment (OR=2.789, p=0.0031). Additionally, scar location within 1 cm of the sternal notch (beta=4.326, p=0.0429) and a history of keloid development (beta=23.082, p<0.0001) were found to be associated with the prognosis of hypertrophic scarring. Conclusion: The findings of this study provide valuable insights into the risk factors associated with hypertrophic scarring following thyroidectomy. Clinicians can use this information to predict the occurrence of hypertrophic scarring and its prognosis, and take preventative measures accordingly.

참고문헌 (9)

  1. Mohamed SE, "Alternate incision-site thyroidectomy", Curr Opin Oncol, 26, pp.22~30 (2014)
  2. 최유리, "Impact of Postthyroidectomy Scar on the Quality of Life of Thyroid Cancer Patients", Annals of Dermatology, 26(6), pp.693~699 (2014), 대한피부과학회
  3. Maurer E, "Alternative approaches in thyroid surgery", Chirurg, 88, pp.675~681 (2017)
  4. Kim JH, "Risk factors for hypertrophic surgical scar development after thyroidectomy", Wound Repair Regen, 20, pp.304~310 (2012)
  5. Butzelaar L, "Going into surgery : risk factors for hypertrophic scarring", Wound Repair Regen, 23, pp.531~537 (2015)
  6. Butzelaar L, "Currently known risk factors for hypertrophic skin scarring : a review", J Plast Reconstr Aesthet Surg, 69, pp.163~169 (2016)
  7. Noishiki C, "Sex differences in keloidogenesis:an analysis of 1659 keloid patients in Japan", Dermatol Ther(Heidelb), 9, pp.747~754 (2019)
  8. Lawrence JW, "Epidemiology and impact of scarring after burn injury : a systematic review of the literature", J Burn Care Res, 33, pp.136~146 (2012)
  9. He J, "Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1", Cell Death Dis, 12, pp.226~ (2021)

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