심리 및 생리적 요인이 성인천식에 미치는 영향
Effects of Psychological and Physiological Factors on Asthma in Korean Adults
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본 연구는 국민건강영양조사(2017) 자료를 이용하여 의사로부터 천식 진단을 받은 대상자의 자가 건강인지도, 스트 레스, 2주 연속 우울감 등의 심리적 요인과 생리적 건강지표인 혈액 검사 자료를 비교하고 관련 위험요인들을 분석하였 다. 연구에 사용된 국민건강영양조사(2017) 전체 대상자 수는 8,127명이며, 그 중의 성인(19세 이상) 5,852명을 대상으 로 자료를 분석하였다. 일반적 특성 중 나이에 따른 천식 발생의 위험도는 65세 이상에서 높이 나타났으며(OR=1.48), 학력(OR=1.89)과 소득(OR=2.07)이 낮을수록 천식질환 발생 위험도가 증가하는 것으로 관찰되었다. 또한, 결혼 상태에 서는 유배우자 동거와 비교하면 미혼(OR=1.62)과 무 배우자(사별, 이혼; OR=2.30)에서 천식 발생확률이 증가하였으며, 천식 진단군은 활동 제한(OR=2.39)이 높은 것으로 확인되었다. 심리적 요인에 있어서는 건강이 나쁘다고 인식할수록 천식 발생 유병률이 증가하였으며(OR=3.45), 우울감을 느끼는 경우도 증가하였지만(OR=1.78), 스트레스는 천식 발생 관련 위험요인이 아닌 것으로 확인되었다. 객관적 검사자료인 생리적 지표에서는 고감도 C-반응성 단백질 수치가 증가할수록 천식 발생 위험도가 증가함이 확인되었다(OR=1.12). 따라서 자가 건강인지도 및 우울감 같은 심리적 요인과 생리적 건강지표 중 하나인 고감도 C-반응성 단백질은 성인천식 질환의 잠재적 위험요인으로 인지되며, 이를 바탕으 로 성인천식 질환 관리에 있어서 일반적 특성뿐만 아니라 심리적 요인 및 생리적 건강지표를 고려한 성인건강 관련 프로그램이 필요할 것으로 생각된다.
Abstract
This study aimed to investigate the association between asthma and emotions, such as depression, stress, and health awareness. We observed the effects of blood indices on asthma in Korean adults. Data from 5852 adults were taken from the 2017 Seventh Korea National Health and Nutrition Examination Survey and analyzed using a multivariate logistic regression model. The probability of asthma occurrence in over 65 years old was higher than in 19-44 years old (OR = 1.48), and asthma occurrence was high in subjects with low educational (OR = 1.89) and income (OR = 2.07) levels. With regard to marital status, singleness and divorce and dye were found to have increased the probability of asthma occurrence by 1.62- and 2.30-folds, respectively. The restriction of activities was another factor that increased with asthma occurrence (OR = 2.39). In terms of emotions, general health awareness was significantly 3.45 times increased the probability of asthma occurrence at their health bad awareness. Furthermore, depression (OR = 1.782) was shown to have increased asthma occurrence. The blood index of C-CRP 1.12 times increased the probability of asthma occurrence. The factors that influenced asthma occurrence were age, education, income, marital status, the restriction of activities, general health awareness, depression, and C-CRP. Emotional factors and blood indices are potential risk factors for the development of asthma in Korean adults. By understanding the increased risks of asthma occurrence with general characteristics and emotional factors and blood indices, the management and prevention of asthma should include the management of emotional factors.
참고문헌 (28)
- Wendy M. Brunner, "Depression and Risk of Incident Asthma in Adults. The CARDIA Study", American Journal of Respiratory and Critical Care Medicine, 189(9), pp.1044~1051 (2014), American Thoracic Society[DOI]
- Supinda Bunyavanich, "Systems biology of asthma and allergic diseases: A multiscale approach", Journal of Allergy and Clinical Immunology, 135(1), pp.31~42 (2015), Elsevier BV[DOI]
- 최길순, "Prevalence and Risk Factors for Depression in Korean Adult Patients with Asthma: Is There a Difference between Elderly and Non-Elderly Patients?", Journal of Korean Medical Science, 29(12), pp.1626~1631 (2014), 대한의학회
- Robert Dantzer, "Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity", European Journal of Pharmacology, 500(1-3), pp.399~411 (2004), Elsevier BV[DOI]
- A. Forster, "Incidence and consequences offalls due to stroke: a systematic inquiry", BMJ, 311(6997), pp.83~86 (1995), BMJ[DOI]
- Miyoshi Fujita, "C-reactive protein levels in the serum of asthmatic patients", Annals of Allergy, Asthma & Immunology, 99(1), pp.48~53 (2007), Elsevier BV[DOI]
- 한규은, "감정노동자들의 부정적 정서가 정서소진에 미치는 영향: 정서조절의 매개효과를 조절하는 상황 요인 검증", 감성과학, 22(4), pp.45~56 (2019), 한국감성과학회[DOI]
- 장은혜, "스트레스에 대한 심리 반응 유형과 심박변이도의 관련성", 감성과학, 21(1), pp.71~82 (2018), 한국감성과학회[DOI]
- 조은희, "제6기 국민건강영양조사 자료에 기초한 성인의 천식 유무에 따른 삶의 질 영향요인", 보건의료산업학회지, 13(3), pp.127~136 (2019), 보건의료산업학회[DOI]
- Hatice Kilic, "The relationship between hs-CRP and asthma control test in asthmatic patients", Allergologia et Immunopathologia, 40(6), pp.362~367 (2012), Elsevier BV[DOI]
- 김혜숙, "Association Between Kimchi Intake and Asthma in Korean Adults: The Fourth and Fifth Korea National Health and Nutrition Examination Survey (2007–2011)", Journal of Medicinal Food, 17(1), pp.172~178 (2014), 한국식품영양과학회[DOI]
- Kim S.H., "Phenotypes of Asthma Obstructive", Lung Disease, 4(1), pp.10~14 (2016)
- Mirjam Kool, "An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma", Immunity, 34(4), pp.527~540 (2011), Elsevier BV[DOI]
- 이재영, "한국 성인의 알레르기 비염 관련요인", 한국산학기술학회논문지, 19(12), pp.749~757 (2018), 한국산학기술학회[DOI]
- Jimmy Lee, "Mean platelet volume in schizophrenia unaltered after 1year of clozapine exposure", Schizophrenia Research, 157(1-3), pp.134~136 (2014), Elsevier BV[DOI]
- Lee, K. H., "Hypertension and diabetes mellitus as risk factors for asthma in Korean adults: the Sixth Korea National Health and Nutrition Examination Survey", International Health, pp.1~7 (2019)[DOI]
- 이태훈, "중증천식의 치료", 대한내과학회지, 93(2), pp.159~171 (2018), 대한내과학회
- Hikmet Tekin Nacaroglu, "Can mean platelet volume be used as a biomarker for asthma?", Advances in Dermatology and Allergology, 3, pp.182~187 (2016), Termedia Sp. z.o.o.[DOI]
- 오연목, "노인 기관지천식", 대한내과학회지, 75(2), pp.153~155 (2008), 대한내과학회
- I S Olafsdottir, "C reactive protein levels are increased in non-allergic but not allergic asthma: a multicentre epidemiological study", Thorax, 60(6), pp.451~454 (2005), BMJ[DOI]
- Program, G. I. f. A., "Global Strategy for Asthma Management and Prevention: 2012 Update", Global Initiative for Asthma Vancouver, ~ (2017)
- Li Qin, "Association between serum uric acid levels and cardiovascular disease in middle-aged and elderly Chinese individuals", BMC Cardiovascular Disorders, 14(1), pp.26~ (2014), Springer Science and Business Media LLC[DOI]
- Kate M. Scott, "Mental disorders among adults with asthma: results from the World Mental Health Survey", General Hospital Psychiatry, 29(2), pp.123~133 (2007), Elsevier BV[DOI]
- 신경아, "Clinical Usefulness of Serum Uric Acid and Resting Heart Rate in the Diagnosis of Metabolic Syndrome in Korean Adults", 대한의생명과학회지, 23(2), pp.118~127 (2017), 대한의생명과학회[DOI]
- Teresa To, "Global asthma prevalence in adults: findings from the cross-sectional world health survey", BMC Public Health, 12(1), pp.204~ (2012), Springer Science and Business Media LLC[DOI]
- Adam Wysokiński, "Platelet parameters (PLT, MPV, P-LCR) in patients with schizophrenia, unipolar depression and bipolar disorder", Psychiatry Research, 237, pp.238~245 (2016), Elsevier BV[DOI]
- 윤미정, "한국 성인의 천식 관련 요인: 2016년도 국민건강영양조사의 2차 자료분석", 성인간호학회지, 31(3), pp.259~268 (2019), 한국성인간호학회[DOI]
- Ziemowit Zietkowski, "Changes in High-Sensitivity C-Reactive Protein in Serum and Exhaled Breath Condensate after Intensive Exercise in Patients with Allergic Asthma", International Archives of Allergy and Immunology, 153(1), pp.75~85 (2010), S. Karger AG[DOI]