Antioxidant Activity and Anti-wrinkle Effect of Rhamnus yoshinoi Methanol Extract
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The objectives of this study were to investigate the antioxidant activity and anti-wrinkle effect of Rhamnus yoshinoi methanol extract (RYME) in a cell-free system. The total polyphenol and flavonoids contents in RYME were 538.4 and 196.3 mg/g, respectively. The electron-donating ability of RYME at 100 μg/mL was 92.5%, while its collagenase and elastase inhibitory effects at 8,000 μg/mL were 53.4 and 41.7%, respectively. In comparison, collagenase and elastase inhibition of the positive control vitamin C were 51.0 and 32.7%, respectively. The present study demonstrated that RYME has high antioxidant activity and effectively inhibited the activities of collagenase and elastase.
Abstract
The objectives of this study were to investigate the antioxidant activity and anti-wrinkle effect of Rhamnus yoshinoi methanol extract (RYME) in a cell-free system. The total polyphenol and flavonoids contents in RYME were 538.4 and 196.3 mg/g, respectively. The electron-donating ability of RYME at 100 μg/mL was 92.5%, while its collagenase and elastase inhibitory effects at 8,000 μg/mL were 53.4 and 41.7%, respectively. In comparison, collagenase and elastase inhibition of the positive control vitamin C were 51.0 and 32.7%, respectively. The present study demonstrated that RYME has high antioxidant activity and effectively inhibited the activities of collagenase and elastase.
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