본문 바로가기
KERD
논문KCI 등재

유전자 T-bet에 의한 분자수준에서의 천식 조절

Molecular Regulation of Asthma by T-bet

2

조회

0

다운로드

0

인용

0

참고문헌

주제분류임상병리학

참고문헌 (88)

  1. "The Th1-Th2 classification of cellular immune responses current thinking and applications in haematological malignancy The immunomodulatory role of CD4-positive cytotoxic T-lymphocytes in health and disease The T-box transcription factor T-bet in immunity and autoimmunity The role of T lymphocytes in asthma Lineage commitment in lymphocytes The role of Th1", Th2 polarization in mucosal immunity Natural and induced regulation of Th1, Th2 cytokine balance, 1999[DOI]
  2. "CD8(+)T cells mediate CD40-independent maturation of dendritic cells in vivo", 189, pp.1875~84 (1999)
  3. "Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis,stronger TCR stimulation induces MAP kinases that control IFN-gamma production", 31, pp.2487~96 (2001)
  4. "Cell fate decision:T-helper 1 and 2 subsets in immune responses", 2, pp.179~88 (2000)
  5. "Regulation of T(H)1 differentiation--controlling the controllers", 3, pp.506~8 (2002)
  6. "Interferon gamma stabilizes the T helper cell type 1 phenotype", 194, pp.165~72 (2001)
  7. "IL-23 and IL-12 have overlapping,but distinct,effects on murine dendritic cells", 168, pp.5448~54 (2002)
  8. "WSX-1 is required for the initiation of Th1 responses and resistance to L.major infection", 15, pp.569~78 (2001)
  9. "Development of Th1-type immune responses requires the type I cytokine receptor TCCR", 407, pp.916~20 (2000)
  10. "Interleukin 21 is a T helper(Th)cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells", 196, pp.969~77 (2002)
  11. "Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells", 11, pp.677~88 (1999)
  12. "Stat6 is necessary and sufficient for IL-4’s role in Th2 differentiation and cell expansion", 166, pp.7276~81 (2001)
  13. "Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism", 9, pp.745~55 (1998)
  14. "The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells", 89, pp.587~96 (1997)
  15. "GATA-3 induces T helper cell type 2(Th2)cytokine expression and chromatin remodeling in committed Th1 cells", 192, pp.105~15 (2000)
  16. "c-maf promotes T helper cell type 2(Th2)and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms", 188, pp.1859~66 (1998)
  17. "The proto- oncogene c-maf is responsible for tissue-specific expression of interleukin-4", 85, pp.973~83 (1996)
  18. "Reduced IFNgamma production in response to IL-12 stimulation and", or reduced IL-12 production in atopic patients, 2000, pp.30, 1250~6
  19. "Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling", 169, pp.4388~98 (2002)
  20. "A novel transcription factor,T-bet,directs Th1 lineage commitment", 100, pp.655~69 (2000)
  21. "T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3", 307, pp.430~3 (2005)
  22. "Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells", 295, pp.338~42 (2002)
  23. "T-box genes and the formation of vertebrate forelimb- and hindlimb specific pattern", 296, pp.57~66 (1999)
  24. "Cloning and characterization of a new member of the T-box gene family", 70, pp.41~8 (2000)
  25. "Impaired type I IFN-induced Jak", STAT signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc-, pp.2004, 173[DOI]
  26. "SOCS-3 inhibits IL-12-induced STAT4 activation by binding through its SH2 domain to the STAT4 docking site in the IL-12 receptor beta2 subunit", 310, pp.1188~93 (2003)
  27. "A role of suppressor of cytokine signaling 3(SOCS3", CIS3, pp.2003, 197[DOI]
  28. "Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes", 168, pp.6506~13 (2002)
  29. "Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet", 295, pp.336~8 (2002)
  30. "T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes", 199, pp.1153~62 (2004)
  31. "Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production", 175, pp.4593~602 (2005)
  32. "Loss of T-bet,but not STAT1,prevents the development of experimental autoimmune encephalomyelitis", 200, pp.79~87 (2004)
  33. "Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation", 193, pp.1087~96 (2001)
  34. "T-bet regulates IgG class switching and pathogenic autoantibody production", 99, pp.5545~50 (2002)
  35. "T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells", 98, pp.15137~42 (2001)
  36. "Direct effects of T-bet and MHC class I expression,but not STAT1,on peripheral NK cell maturation", 35, pp.757~65 (2005)
  37. "T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells", 20, pp.477~94 (2004)
  38. "T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells", 100, pp.7749~54 (2003)
  39. "T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression", 176, pp.1036~45 (2006)
  40. "Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells", 101, pp.12622~7 (2004)
  41. "Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-gamma promoter", 15, pp.1149~60 (2003)
  42. "A minimal IFN-gamma promoter confers Th1 selective expression", 169, pp.4205~12 (2002)
  43. "T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site", 102, pp.2034~9 (2005)
  44. "Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin", 6, pp.1236~44 (2005)
  45. "Inducible covalent posttranslational modification of histone H3", 2005 (2005)
  46. "Post-translational modifications influence transcription factor activity:a view from the ETS superfamily", 27, pp.285~98 (2005)
  47. "Regulatory functions of ubiquitination in the immune system", 3, pp.20~6 (2002)
  48. "Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells", 170, pp.2427~34 (2003)
  49. "Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes", 12, pp.537~46 (2000)
  50. "Long-term survival but impaired homeostatic proliferation of Naive T cells in the absence of p56lck", 290, pp.127~31 (2000)
  51. "Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinases", 272, pp.6073~7 (1997)
  52. "Interleukin-2:inception,impact,and implications", 240, pp.1169~76 (1988)
  53. "An IL-4-independent and CD25- mediated function of c-maf in promoting the production of Th2 cytokines", 99, pp.13026~30 (2002)
  54. "Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment", 202, pp.793~804 (2005)
  55. "Stat5 activation plays a critical role in Th2 differentiation", 19, pp.739~48 (2003)
  56. "Transcriptional regulation of the IL-2 gene", 7, pp.333~42 (1995)
  57. "The architecture of the interleukin-2 promoter:a reflection of T lymphocyte activation", 1263, pp.181~200 (1995)
  58. "NFATc1 and NFATc2 together control both T and B cell activation and differentiation", 14, pp.13~20 (2001)
  59. "RelA", p65 is a molecular target for the immunosuppressive action of protein kinase A, 1995, pp.14, 1991~2004
  60. "The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family:c-Rel,p50,and p65", 90, pp.1696~700 (1993)
  61. "c-Rel is required for chromatin remodeling across the IL-2 gene promoter", 170, pp.3724~31 (2003)
  62. "Regulation of NF-kappaB transcriptional activity", 130, pp.89~102 (2006)
  63. "IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508", 202, pp.1289~300 (2005)
  64. "Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome", 167, pp.2657~65 (2001)
  65. "Early activation signal transduction pathways of Th1 and Th2 cell clones stimulated with anti-CD3.Roles of protein tyrosine kinases in the signal for IL-2 and IL-4 production", 155, pp.4692~701 (1995)
  66. "IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells", 23, pp.513~22 (2003)
  67. "A role for IL-27 in early regulation of Th1 differentiation", 175, pp.2191~200 (2005)
  68. "IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression", 31, pp.1055~65 (2001)
  69. "IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response", 169, pp.3600~5 (2002)
  70. "Regulation of cytokine signaling and inflammation", 13, pp.413~21 (2002)
  71. "A mutant form of JAB", SOCS1 augments the cytokine- induced JAK, CIS family proteins through the SOCS-box, 2001[DOI]
  72. "Inhibitors of gamma- secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21", 6, pp.680~8 (2005)
  73. "Activation of signaling lymphocytic activation molecule triggers a signaling cascade that enhances Th1 responses in human intracellular infection", 173, pp.4120~9 (2004)
  74. "Nonredundant roles of Sema4A in the immune system:defective T cell priming and Th1", Th2 regulation in Sema4A-deficient mice, 2005, pp.22, 305~16
  75. "T-bet-dependent expression of osteopontin contributes to T cell polarization", 102, pp.17101~6 (2005)
  76. "T-bet is required for optimal proinflammatory CD4+ T-cell trafficking", 106, pp.3432~9 (2005)
  77. "Cutting edge:differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells", 167, pp.628~31 (2001)
  78. "A crucial role for T-bet in selectin ligand expression in T helper 1(Th1)cells", 106, pp.3867~73 (2005)
  79. "Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27", 175, pp.1686~93 (2005)
  80. "Control of effector CD8+ T cell function by the transcription factor Eomesodermin", 302, pp.1041~3 (2003)
  81. "Asthmatic changes in mice lacking T-bet are mediated by IL-13", 17, pp.993~1007 (2005)
  82. "Regulation of T cells in asthma:implications for genetic manipulation", 4, pp.69~74 (2004)
  83. "T cell directives for transcriptional regulation in asthma", 25, pp.281~94 (2004)
  84. "Complement component C3:molecular basis of the C3*S025 variant and evidence for molecular heterogeneity of other variants", 96, pp.539~41 (1995)
  85. "TBX21:a functional variant predicts improvement in asthma with the use of inhaled corticosteroids", 101, pp.18099~104 (2004)
  86. "Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma", 117, pp.16~26 (2005)
  87. "T-bet polymorphisms are associated with asthma and airway hyperresponsiveness", 173, pp.64~70 (2006)
  88. "T-bet polymorphisms are associated with asthma and airway hyperresponsiveness", 173, pp.64~70 (2006)

관련 논문AI추천

이 간행물의 다른 논문 (11건)