척추관절병증의 치료에 대한 최신지견
Updates of Spondyloarthrothy Treatment
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초록
2000년대 들면서 류마티스질환은 조기 진단 및 조기치료를 목표로 한다. MRI와 종양괴사인자-α 길항제 소개로 척추관절염의 조기 진단 및 조기치료에 혁신적인 변화를 일으켰다. 비스테로이성 항염제가 가장 중요한 치료약제이고 장기간 사용 시 강직 예방효과를 기대하고 있다. 종양괴사인자-α 길항제는 탁월한 효과를 보이나 결핵, 감염 등 부작용 가능성은 항상 염두에 두어야 한다. 척추관절염의 경과는 양호한경우가 많으므로 꾸준한 운동 및 재활 등 자기 관리가 중요하고 적절한 약물치료가 필요한 질환이다.
Abstract
The goals of treatment in Spondyloarthropathy are to reduce pain and stiffness, and to maintain good quality of life. Regular exercise with stretching of axial skeleton is most important. No drugs have been prevented ankylosis, but non steroidal anti inflammatory drugs (NSAIDs) are the first line drugs and these are very effective in most of patients who have inflammatory back pain. In recent years, reports that long-term use of NSAIDs may reduce the ankylosis are coming out and expect NSAIDs as anti ankylosis drugs. If NSAIDs is not effective, anti TNF agents can be used in severe inflammatory back pain. In peripheral arthritis, sulfasalazine or steoids can be used, and If these are failed, anti TNF agents can be used.
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