Diet-induced obesity and aging-induced upregulation of Trib3 interfere with energy homeostasis by downregulating the thermogenic capacity of BAT

참고문헌 (60)

1. Kim, M. S., "The neural basis of weight control and obesity", Exp. Mol. Med, 54, pp.347~348 (2022)
2. Timmons, J. A., "Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages", Proc. Natl. Acad. Sci. USA, 104, pp.4401~4406 (2007)
3. Chouchani, E. T., "New advances in adaptive thermogenesis : UCP1 and beyond", Cell Metab, 29, pp.27~37 (2019)
4. Kang, G. S., "Sensing the oxygen and temperature in the adipose tissues -who’s sensing what?", Exp. Mol. Med, 55, pp.2300~2307 (2023)
5. Mata, J., "Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string", CDC25 proteolysis, 2000, pp.101, 511~522
6. Seher, T. C., "Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation", Curr. Biol, 10, pp.623~629 (2000)
7. Kwon, A., "Tracing the origin and evolution of pseudokinases across the tree of life", Sci. Signal, 12 (2019)[DOI]
8. Kiss-Toth, E., "Human tribbles, a protein family controlling mitogen-activated protein kinase cascades", J. Biol. Chem, 279, pp.42703~42708 (2004)
9. Sung, H. Y., "Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways", J. Biol. Chem, 282, pp.18379~18387 (2007)
10. Bailey, F. P., "The tribbles 2(TRB2)pseudokinase binds to ATP and autophosphorylates in a metal-independent manner", Biochem. J, 467, pp.47~62 (2015)
11. Murphy, J. M., "Molecular mechanism of CCAAT-enhancer binding protein recruitment by the TRIB1 pseudokinase", Structure, 23, pp.2111~2121 (2015)
12. Du, K., "TRB3: a tribbles homolog that inhibits Akt", PKB activation by insulin in liver, 2003, pp.300, 1574~1577
13. Wang, D., "TRIB2-mediated modulation of AMPK promotes hepatic insulin resistance", Diabetes (2024)[DOI]
14. Hernandez-Resendiz, I., "Novel functions of Tribbles-homolog 1 in liver, adipocytes and atherosclerosis", Curr. Opin. Lipido, 35, pp.51~57 (2024)
15. Bi, X. P., "Overexpression of TRB3 gene in adipose tissue of rats with high fructose-induced metabolic syndrome", Endocr. J, 55, pp.747~752 (2008)
16. Koh, H. J., "Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle", Nat. Commun, 4, pp.1871~ (2013)
17. Kwon, M., "Skeletal muscle tissue Trib3 links obesity with insulin resistance by autophagic degradation of AKT2", Cell Physiol. Biochem, 48, pp.1543~1555 (2018)
18. Qi, L., "TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism", Science, 312, pp.1763~1766 (2006)
19. Sun, X., "TRB3 gene silencing activates AMPK in adipose tissue with beneficial metabolic effects in obese and diabetic rats", Biochem. Biophys. Res. Commun, 488, pp.22~28 (2017)
20. Zhang, W., "Skeletal muscle TRIB3 mediates glucose toxicity in diabetes and high fat diet-induced insulin resistance", Diabetes (2016)[DOI]
21. Satoh, T., "Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages", Nature, 495, pp.524~528 (2013)
22. Kim, D., "Suppression of brown adipocyte autophagy improves energy metabolism by regulating mitochondrial turnover", Int. J. Mol. Sci, 20 (2019)[DOI]
23. Muller, T. D., "Revisiting energy expenditure : how to correct mouse metabolic rate for body mass", Nat. Metab, 3, pp.1134~1136 (2021)
24. Kim, Y. H., "NEDD4L limits cAMP signaling through ubiquitination of CREBregulated transcription coactivator 3", FASEB J, 32, pp.4053~4062 (2018)
25. Salazar, M., "TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action", Autophagy, 5, pp.1048~1049 (2009)
26. Pellegrini, C., "Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy : an in vitro and in vivo study of adipose tissue browning", Exp. Mol. Med, 51, pp.1~17 (2019)
27. Richard, D., "Brown fat biology and thermogenesis", Front. Biosci, 16, pp.1233~1260 (2011)
28. Fischer, A. W., "Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice", J. Lipid Res, 61, pp.1377~1389 (2020)
29. Wei, Y., "Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells", Am. J. Physiol. Endocrinol. Metab, 291, pp.E275~281 (2006)
30. Schmitz-Peiffer, C., "Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes", Diabetes, 57, pp.1774~1783 (2008)
31. Geraldes, P., "Activation of protein kinase C isoforms and its impact on diabetic complications", Circ. Res, 106, pp.1319~1331 (2010)
32. Prudente, S., "The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases", Endocr. Rev, 33, pp.526~546 (2012)
33. Bartelt, A., "Brown adipose tissue activity controls triglyceride clearance", Nat. Med, 17, pp.200~205 (2011)
34. Zhang, X., "Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder", Cell Death Dis, 12, pp.1098~ (2021)
35. Bezy, O., "TRB3 blocks adipocyte differentiation through the inhibition of C", EBPbeta transcriptional activity, 2007, pp.27, 6818~6831
36. Jeong, H. W., "Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling", Biochem. Biophys. Res. Commun, 470, pp.783~791 (2016)
37. Morrison, R. F., "Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c)and p21(Waf1", Cip1), during adipogenesis, 1999, pp.274, 17088~17097
38. Inoue, N., "Cyclin-dependent kinase inhibitor, p21WAF1", CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance, 2008, pp.283, 21220~21229
39. Scime, A., "Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha", Cell Metab, 2, pp.283~295 (2005)
40. Sakai, S., "Dual mode of regulation of cell division cycle 25 A protein by TRB3", Biol. Pharm. Bull, 33, pp.1112~1116 (2010)
41. Geng, T., "Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3 : a potential link between dietary fat composition and the pathophysiological outcomes of obesity", Diabetologia, 56, pp.2078~2087 (2013)
42. Liu, J., "Mammalian tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance", Am. J. Physiol. Endocrinol. Metab, 298, pp.E565~576 (2010)
43. Liu, J., "Role of TRIB3 in regulation of insulin sensitivity and nutrient metabolism during short-term fasting and nutrient excess", Am. J. Physiol. Endocrinol. Metab, 303, pp.E908~E916 (2012)
44. Lima, A. F., "Acute exercise reduces insulin resistance-induced TRB3expression and amelioration of the hepatic production of glucose in the liver of diabetic mice", J. Cell. Physiol, 221, pp.92~97 (2009)
45. Morse, E., "TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1", Am. J. Physiol. Ren. Physiol, 299, pp.F965~972 (2010)
46. Liew, C. W., "The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells", J. Clin. Investig, 120, pp.2876~2888 (2010)
47. Rasmussen, T. L., "Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses", PLoS ONE, 10, pp.e0121765~ (2015)
48. Zhou, Y., "E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3", Cell. Signal, 20, pp.942~948 (2008)
49. Wertz, I. E., "Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase", Science, 303, pp.1371~1374 (2004)
50. Ouyang, W., "Erk1", 2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates, 2020, pp.117, 4078~4087
51. Benoit, S. C., "Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents", J. Clin. Investig, 119, pp.2577~2589 (2009)
52. Gassaway, B. M., "PKCepsilon contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling", Proc. Natl. Acad. Sci. USA, 115, pp.E8996~E9005 (2018)
53. Paz Gavilan, M., "Cellular environment facilitates protein accumulation in aged rat hippocampus", Neurobiol. Aging, 27, pp.973~982 (2006)
54. Hussain, S. G., "Reduced eIF2alpha phosphorylation and increased proapoptotic proteins in aging", Biochem. Biophys. Res. Commun, 355, pp.365~370 (2007)
55. Ogata, M., "Autophagy is activated for cell survival after endoplasmic reticulum stress", Mol. Cell. Biol, 26, pp.9220~9231 (2006)
56. Brown, M. K., "The endoplasmic reticulum stress response in aging and age-related diseases", Front. Physiol, 3, pp.263~ (2012)
57. Ando, A., "Deoxysphingolipids and ether-linked diacylglycerols accumulate in the tissues of aged mice", Cell Biosci, 9, pp.61~ (2019)
58. Graja, A., "Mechanisms of aging-related impairment of brown adipocyte development and function", Gerontology, 61, pp.211~217 (2015)
59. Darcy, J., "ComBATing aging-does increased brown adipose tissue activity confer longevity?", Geroscience, 41, pp.285~296 (2019)
60. Singh, A. B., "Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice", Sci. Rep, 9, pp.15641~ (2019)

관련 논문AI추천