Primary Multiple Cardiac Myxomas in a Patient without the Carney Complex
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Cardiac tumors are rare, and multiple myxomas are even rarer. The latter phenomenon is mostly associated with the Carney complex, a dominantly inherited disease characterized by multiple primary cardiac myxomas, endocrinopathy, and spotty pigmentation of the skin. We report the rare case of a patient who did not have the Carney complex but had multiple primary cardiac tumors. A 78-year-old woman with a past history of breast cancer was referred to our hospital for further examination of multiple cardiac tumors. Echocardiography showed 4 tumors in the left atrium and left ventricle. We could not diagnose them preoperatively and decided to resect them surgically because they were mobile and could have caused embolism and obstruction. The postoperative pathological findings of all 4 tumors were myxomas, although the patient did not meet the diagnostic criteria of the Carney complex. Therefore, a rare case of multiple primary cardiac myxomas was diagnosed.
Abstract
Cardiac tumors are rare, and multiple myxomas are even rarer. The latter phenomenon is mostly associated with the Carney complex, a dominantly inherited disease characterized by multiple primary cardiac myxomas, endocrinopathy, and spotty pigmentation of the skin. We report the rare case of a patient who did not have the Carney complex but had multiple primary cardiac tumors. A 78-year-old woman with a past history of breast cancer was referred to our hospital for further examination of multiple cardiac tumors. Echocardiography showed 4 tumors in the left atrium and left ventricle. We could not diagnose them preoperatively and decided to resect them surgically because they were mobile and could have caused embolism and obstruction. The postoperative pathological findings of all 4 tumors were myxomas, although the patient did not meet the diagnostic criteria of the Carney complex. Therefore, a rare case of multiple primary cardiac myxomas was diagnosed.
참고문헌 (10)
- Bossert T, "Surgical experience with 77 primary cardiac tumors", Interact Cardiovasc Thorac Surg, 4, pp.311~315 (2005)
- MacGowan SW, "Atrial myxoma: national incidence, diagnosis and surgical management", Ir J Med Sci, 162, pp.223~226 (1993)
- Hoffmeier A, "Neoplastic heart disease -- the Muenster experience with 108 patients", Thorac Cardiovasc Surg, 53, pp.1~8 (2005)
- Raimann A, "Cushing, hypertonie, sommersprossen. Der Carney-komplex: fallbericht eines seltenen neoplasiesyndroms", J Clin Endocrinol Metab, 2, pp.22~25 (2009)
- Rahbar K, "Differentiation of malignant and benign cardiac tumors using 18F-FDG PET", CT, 2012, pp.53, 856~863
- Sablotzki A, "Plasma levels of immunoinhibitory cytokines interleukin-10and transforming growth factor-beta in patients undergoing coronary artery bypass grafting", Eur J Cardiothorac Surg, 11, pp.763~768 (1997)
- Markewitz A, "Alterations of cell-mediated immunity following cardiac operations:clinical implications and open questions", Shock, 16(Suppl 1), pp.10~15 (2001)
- Pinto CA, "Cardiopulmonary bypass has a modest association with cancer progression:a retrospective cohort study", BMC Cancer, 13, pp.519~ (2013)
- Canver CC, "Should a patient with a treated cancer be offered an open heart operation?", Ann Thorac Surg, 55, pp.1202~1204 (1993)
- Carrascal Y, "Cardiac surgery with extracorporeal circulation in cancer patients: influence on surgical morbidity and mortality and on survival", Rev Esp Cardiol, 61, pp.369~375 (2008)
