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Acute Myocardial Infarction due to Cardiac Allograft Vasculopathy: An Autopsy Report

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초록

After the Organ Transplant Act was enforced in 2000, the criteria for the diagnosis of brain death have been legalized, and cardiac transplantation has become a promising treatment choice for patients with chronic heart disease. Even though more than hundreds of cases have been accumulated in the national registry and the survival rates are increasing, the compliance of long-term survivors may decrease paradoxically, which can hinder the efforts to enhance the quality of the registry. The patients who are lost from the doctor’s surveillance and die outside hospitals should be appropriately examined to determine the cause of death so that the influence of their medical condition, if any, on their death could be revealed. Here, we report an autopsy case of a patient who died of a complication of chronic rejection after cardiac transplantation.

Abstract

After the Organ Transplant Act was enforced in 2000, the criteria for the diagnosis of brain death have been legalized, and cardiac transplantation has become a promising treatment choice for patients with chronic heart disease. Even though more than hundreds of cases have been accumulated in the national registry and the survival rates are increasing, the compliance of long-term survivors may decrease paradoxically, which can hinder the efforts to enhance the quality of the registry. The patients who are lost from the doctor’s surveillance and die outside hospitals should be appropriately examined to determine the cause of death so that the influence of their medical condition, if any, on their death could be revealed. Here, we report an autopsy case of a patient who died of a complication of chronic rejection after cardiac transplantation.

참고문헌 (9)

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  5. Wilhelm MJ, "Long-term outcome following heart transplantation: current perspective", J Thorac Dis, 7, pp.549~551 (2015)
  6. Skoric B, "Cardiac allograft vasculopathy: diagnosis, therapy, and prognosis", Croat Med J, 55, pp.562~576 (2014)[DOI]
  7. Mehra MR, "International Society for Heart and Lung Transplantation working formulation of a standardized nomenclature for cardiac allograft vasculopathy-2010", J Heart Lung Transplant, 29, pp.717~727 (2010)[DOI]
  8. Alexander RT, "Cause of death and sudden cardiac death after heart transplantation: an autopsy study", Am J Clin Pathol, 119, pp.740~748 (2003)[DOI]
  9. 정성호, "Long-term Mortality in Adult Orthotopic Heart Transplant Recipients", Journal of Korean Medical Science, 26(5), pp.599~603 (2011), 대한의학회

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