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논문KCI 등재

코골이가 수면무호흡증의 중증도를 예측할 수 있을까?

Has Snoring Significance for Predicting Obstructive Sleep Apnea Severity?

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주제분류신경과학

초록

Background: The aim of this study was to investigate the predictive value of snoring frequency in the diagnosis and severity of obstructive sleep apnea. Methods: Patients who underwent polysomnography with one or more of the following characteristics were included: 1) sleepiness, non-restorative sleep, fatigue, or insomnia symptoms; 2) arousal due to cessation of breathing or the occurrence of gasping or choking when waking up; and 3) habitual snoring, breathing interruptions, or both, noted by a bed partner or other observer. We analyzed the differences in clinical and polysomnographic variables between patients with and without obstructive sleep apnea and investigated the associations of those variables with obstructive sleep apnea severity. Results: One hundred ninety-three patients met the inclusion criteria, and 145 of the 193 patients were diagnosed with obstructive sleep apnea. Multiple logistic regression analysis showed that large neck circumference (p = 0.0054) and high snoring index (p = 0.0119) were independent predictors for obstructive sleep apnea. Moreover, between the obstructive sleep apnea severity groups, there was a strong tendency of difference in body mass index (p = 0.0441) and neck circumference (p = 0.0846). However, there was no significant difference in snoring frequency according to obstructive sleep apnea severity (p = 0.4914). Conclusions: We confirmed that snoring frequency is a predictor of obstructive sleep apnea. In addition, we showed for the first time that snoring frequency is not associated with obstructive sleep apnea severity, thus it is not a valuable marker for predicting obstructive sleep apnea severity. (Korean J Clin Neurophysiol 2015;17:61-67)

Abstract

Background: The aim of this study was to investigate the predictive value of snoring frequency in the diagnosis and severity of obstructive sleep apnea. Methods: Patients who underwent polysomnography with one or more of the following characteristics were included: 1) sleepiness, non-restorative sleep, fatigue, or insomnia symptoms; 2) arousal due to cessation of breathing or the occurrence of gasping or choking when waking up; and 3) habitual snoring, breathing interruptions, or both, noted by a bed partner or other observer. We analyzed the differences in clinical and polysomnographic variables between patients with and without obstructive sleep apnea and investigated the associations of those variables with obstructive sleep apnea severity. Results: One hundred ninety-three patients met the inclusion criteria, and 145 of the 193 patients were diagnosed with obstructive sleep apnea. Multiple logistic regression analysis showed that large neck circumference (p = 0.0054) and high snoring index (p = 0.0119) were independent predictors for obstructive sleep apnea. Moreover, between the obstructive sleep apnea severity groups, there was a strong tendency of difference in body mass index (p = 0.0441) and neck circumference (p = 0.0846). However, there was no significant difference in snoring frequency according to obstructive sleep apnea severity (p = 0.4914). Conclusions: We confirmed that snoring frequency is a predictor of obstructive sleep apnea. In addition, we showed for the first time that snoring frequency is not associated with obstructive sleep apnea severity, thus it is not a valuable marker for predicting obstructive sleep apnea severity. (Korean J Clin Neurophysiol 2015;17:61-67)

참고문헌 (26)

  1. Vaessen TJ, "Cognitive complaints in obstructive sleep apnea", Sleep Med Rev, 19, pp.51~58 (2015)
  2. Farney RJ, "The STOP-Bang equivalent model and prediction of severity of obstructive sleep apnea: relation to polysomnographic measurements of the apnea", hypopnea index, 2011, pp.7, 459~465
  3. Epstein LJ, "Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults", J Clin Sleep Med, 5, pp.263~276 (2009)
  4. Chung F, "STOP questionnaire: a tool to screen patients for obstructive sleep apnea", Anesthesiology, 108, pp.812~821 (2008)
  5. Beck R, "The acoustic properties of snores", Eur Respir J, 8, pp.2120~2128 (1995)
  6. Ng AK, "Could formant frequencies of snore signals be an alternative means for the diagnosis of obstructive sleep apnea?", Sleep Med, 9, pp.894~898 (2008)
  7. Wilson K, "The snoring spectrum: acoustic assessment of snoring sound intensity in 1,139 individuals undergoing polysomnography", Chest, 115, pp.762~770 (1999)
  8. Ben-Israel N, "Obstructive apnea hypopnea index estimation by analysis of nocturnal snoring signals in adults", Sleep, 35, pp.1299~1305 (2012)
  9. Sateia MJ., "International classification of sleep disorders-third edition:highlights and modifications", Chest, 146, pp.1387~1394 (2014)
  10. Berry RB, "Rules for scoring respiratory events in sleep: update of the 2007AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine", J Clin Sleep Med, 8, pp.597~619 (2012)
  11. Cho YW, "The reliability and validity of the Korean version of the Epworth sleepiness scale", Sleep Breath, 15, pp.377~384 (2011)
  12. Cavusoglu M, "Investigation of sequential properties of snoring episodes for obstructive sleep apnoea identification", Physiol Meas, 29, pp.879~898 (2008)
  13. Perez-Padilla JR, "Characteristics of the snoring noise in patients with and without occlusive sleep apnea", Am Rev Respir Dis, 147, pp.635~644 (1993)
  14. Fiz JA, "Continuous analysis and monitoring of snores and their relationship to the apnea-hypopnea index", Laryngoscope, 120, pp.854~862 (2010)
  15. Sola-Soler J, "Multiclass classification of subjects with sleep apnoea-hypopnoea syndrome through snoring analysis", Med Eng Phys, 34, pp.1213~1220 (2012)
  16. Maimon N, "Does snoring intensity correlate with the severity of obstructive sleep apnea?", J Clin Sleep Med, 6, pp.475~478 (2010)
  17. Li KK, "Obstructive sleep apnea syndrome: a comparison between Far-East Asian and white men", Laryngoscope, 110, pp.1689~1693 (2000)
  18. Wang J, "Asians have lower body mass index (BMI) but higher percent body fat than do whites: comparisons of anthropometric measurements", Am J Clin Nutr, 60 (1994)
  19. Sakakibara H, "Cephalometric abnormalities in non-obese and obese patients with obstructive sleep apnoea", Eur Respir J, 13, pp.403~410 (1999)
  20. Gavriely N, "Theory and measurements of snores", J Appl Physiol, 74, pp.2828~2837 (1993)
  21. Guilleminault C, "Snoring (I). Daytime sleepiness in regular heavy snorers", Chest, 99, pp.40~48 (1991)
  22. Azarbarzin A, "Snoring sounds variability as a signature of obstructive sleep apnea", Med Eng Phys, 35, pp.479~485 (2013)
  23. Sharma SK, "A stepped approach for prediction of obstructive sleep apnea in overtly asymptomatic obese subjects: a hospital based study", Sleep Med, 5, pp.351~357 (2004)
  24. Karakoc O, "The upper airway evaluation of habitual snorers and obstructive sleep apnea patients", ORL J Otorhinolaryngol Relat Spec, 74, pp.136~140 (2012)
  25. Villaneuva AT, "Ethnicity and obstructive sleep apnoea", Sleep Med Rev, 9, pp.419~436 (2005)
  26. Herzog M, "Analysed snoring sounds correlate to obstructive sleep disordered breathing", Eur Arch Otorhinolaryngol, 265, pp.105~113 (2008)

관련 논문AI추천

Predictors for Presence and Severity of Obstructive Sleep Apnea in Snoring Patients: Significance of Neck Circumference김시은, 박강민, 박봉수, 박시형, 박진세, 신경진, 하삼열대한수면연구학회 · Journal of sleep medicine2015 · 제12권 제2호폐쇄성 무호흡증 환자에서 코골이 시간(%)의 임상적 의의강태욱, 김경래, 김선욱, 성의숙, 윤병기, 조석현, 최지혜대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2016 · 제59권 제9호폐쇄성 수면무호흡증 환자의 과도한 주간졸음의 예측인자강병욱, 김정수, 김준영, 박성파, 이다인, 이호원대한수면연구학회 · Journal of sleep medicine2008 · 제5권 제1호Relationship Between Snoring Intensity and Severity of Obstructive Sleep Apnea김정훈, 모지훈, 이재서, 이철희대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2015 · 제8권 제4호폐쇄성 수면무호흡증 환자에서 신체적 특성이 수면 장애와 심혈관계합병증 발병에 미치는 영향: 예비연구강승걸, 고재진, 김선태, 김지언, 박기형, 신승헌, 예미경대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2015 · 제58권 제11호폐쇄성 수면무호흡증과 삶의 질 : 예비연구김정수, 박성파, 송선희, 윤창호, 이만기, 이종태, 이호원, 최재갑대한수면연구학회 · Journal of sleep medicine2006 · 제3권 제1호

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