滋陰八味煎이 卵巢摘出 白鼠의 骨多孔症에 미치는 影響
Effects of Jaeumpalmijeon on the Ovariectomized Rat Model of Postmenopausal Osteoporosis
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Abstract
Purpose : This study is to examine what are the effects of the Jaeumpalmijeon(JPJ) on the ovariectomized rat model of postmenopausal osteoporosis. Methods : 12weeks Female Sprague-Dawley 30 rats of weighting 250-300g, were divided into three groups including the sham operation groups(10heads) and overiectomy groups(10heads). then we observed changes in the body weight, serum metabolic products and femoral trabecular bone. Results : 1. Body weight in control group showed significant increase in comparison with sham, but that in JPJ-treated showed no change in comparison with control. 2. The level of serum albumin in control group showed significant decrease in comparison with sham. That in JPJ-treated was slightly decreased in comparison with control. 3. The level of serum ALP activity in control group showed significant increase in comparison with sham, but that in JPJ-treated was significantly decreased in comparison with control. 4. The level of serum AST in control group showed no change in comparison with sham, but that in JPJ-treated was significantly decreased in comparison with control. The level of serum ALT did not significant change among the three groups. 5. Trabecular bone area as well as trabecular thickness in control group showed significant decrease in comparison with sham. Those in JPJ-treated showed significant increase in comparison with control. 6. Trabecular separation in control group showed significant increase in comparison with sham. Those in JPJ-treated showed significant decrease in comparison with control. 7. Osteoclast number and oseoblast surface in control group showed significant increase in comparison with sham. Those in JPJ-treated showed significant decrease in comparison with control. Conclusion : JPJ has shown to be capable of preventing and curing osteoporosis caused by old-aged and postmenopause.
참고문헌 (33)
- "임상 내분비학", pp.325~ (1990), 고려의학
- "骨多孔症의 東醫學的 臨床文獻에 관한 考察", 7(1), pp.437~456 (1997)
- "골다공증의 한의학적 치료에 대한 문헌적 고찰", 4, pp.107~127 (2000)
- "紫河車가 卵巢摘出로 骨多孔症이 誘發된 흰쥐에 미치는 影響" (1998), 圓光大學校 大學院
- "紫河車 煎湯液이 卵巢摘出로 誘發된 흰쥐의 骨多孔症에 미치는 影響", 16(4), pp.213~221 (1999)
- "紅花子가 卵巢를 摘出한 白鼠의 骨多孔症에 미치는 影響", 14(1), pp.73~87 (2001)
- "接骨木 煎湯液이 卵巢摘出로 骨多孔症이 誘發된 白鼠에 미치는 影響", 13(1), pp.263~303 (2000)
- "大補元煎이 卵巢摘出로 骨多孔症이 誘發된 白鼠에 미치는 影響", 12(1), pp.343~363 (1999)
- "毓麟珠가 卵巢摘出 白鼠의 骨多孔症에 미치는 影響" (2002), 圓光大學校 大學院
- "當歸地黃飮이 卵巢摘出 白鼠의 骨多孔症에 미치는 影響" (2003), 圓光大學校 大學院
- "歸腎丸이 卵巢摘出 白鼠의 骨多孔症에 미치는 影響" (2004), 圓光大學校 大學院
- "身痛逐瘀湯이 卵巢摘出 白鼠의 骨多孔症에 미치는 影響" (2004), 圓光大學校 大學院
- "갱년기 치료의 실제", pp.6~ (1995), 한국의학
- "폐경후 여성에서 Ipriflavoned의 골밀도 및 골대사에 미치는 영향에 관한 연구", 38(7), pp.1244~1252 (1995)
- "臟腑辨證論治", pp.286~ (1985), 成輔社
- "東醫再活醫學科學", pp.34~37 (1995), 書苑堂
- "갱년기장애의 치료에 대한 연구(骨多孔症)", 32(2), pp.109~136 (1996)
- "骨多孔症에 대한 東西醫學的 考察", 6(1), pp.293~315 (1996)
- "갱년기 장애중 골다공증에 대한 문헌적 고찰", 6(1), pp.493~505 (1997)
- "골다공증의 (骨多孔症) 침구치료에 관한 문헌적 고찰", 11(2), pp.171~191 (1995)
- "Progressive cancellous bone ioss in rats after adrenaectomy and oophorectomy", pp.383~387 (1990)
- "The ovariectomized rat model of postmenopausal bone loss", pp.447~452 (1992)
- "Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats", endocri(logy), pp.1146~1150 (1988)
- "Skeletal alterations in ovariectomized rats", pp.324~328 (1985)
- "Effect of body weight in osteopenia in ovariectomized rats", pp.155~159 (1987)
- "Characteristics of an ovariectomized rat model", pp.13~22 (1989)
- "Effects of oophorectomy on biochemical and bone variables in the rat", pp.133~142 (1992)
- "오늘의 진단 및 치료", pp.1218~ (1999), 도서출판 한우리
- "Principle of Bone Biology" (1996), Academic Press
- "Effects of 17β-estradiol replacement and tresdmill exercise on vertevral and femoral bones of the ovarectomized rat", pp.223~234 (1994)
- "Progressive cancellous bone loss in rats after adrenaectomy and oophorectomy", pp.383~387 (1990)
- "Bone changes after castration in rats A model for osteoporosis", pp.67~70 (1986)
- "Comparison of methods for defining prevalent vertebral deformities the study of Osteoporotic Fractures", 10(6), pp.890~902 (1995)
