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Basic Therapeutic Approach for Patients with Plaque Psoriasis: Korean Expert Consensus Using the Modified Delphi Method

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초록

Background: Currently, there is no consensus on the treatment of psoriasis in Korean pa- tients. Objective: This study aimed to establish a consensus on the basic therapeutic principles for Korean patients with plaque psoriasis. Methods: Using the modified Delphi method, a steering committee proposed 53 statements for the first Delphi round, which covered five subjects: (1) the goal of treatment and evalu- ation of disease severity, (2) topical therapy, (3) phototherapy, (4) conventional systemic therapy, and (5) biologic therapy. The panel of dermatologists scored the level of agreement for each statement on a ten-point scale with scores ranging from 1 (strongly disagree) to 10 (strongly agree). After discussing the results of the first round, the committee reformulated 41 statements. Finally, consensus was defined as more than 70% of the second round scores being ≥7. Results: The panel participants strongly agreed that the ideal treatment goals for Korean pa- tients with plaque psoriasis should include complete skin clearance and high dermatological quality of life. A strong consensus was also reached on the use of topical agents for psoriasis of any severity, the consideration of phototherapy before biologics therapy, the conventional systemic agents for moderate-to-severe psoriasis, and the recommendation of biologic for retractable psoriasis to conventional systemic therapy and phototherapy. Conclusion: This modified Delphi panel established an expert consensus on the therapeutic approach for Korean patients with plaque psoriasis. This consensus may improve the treat- ment outcomes for psoriasis in Korea.

Abstract

Background: Currently, there is no consensus on the treatment of psoriasis in Korean pa- tients. Objective: This study aimed to establish a consensus on the basic therapeutic principles for Korean patients with plaque psoriasis. Methods: Using the modified Delphi method, a steering committee proposed 53 statements for the first Delphi round, which covered five subjects: (1) the goal of treatment and evalu- ation of disease severity, (2) topical therapy, (3) phototherapy, (4) conventional systemic therapy, and (5) biologic therapy. The panel of dermatologists scored the level of agreement for each statement on a ten-point scale with scores ranging from 1 (strongly disagree) to 10 (strongly agree). After discussing the results of the first round, the committee reformulated 41 statements. Finally, consensus was defined as more than 70% of the second round scores being ≥7. Results: The panel participants strongly agreed that the ideal treatment goals for Korean pa- tients with plaque psoriasis should include complete skin clearance and high dermatological quality of life. A strong consensus was also reached on the use of topical agents for psoriasis of any severity, the consideration of phototherapy before biologics therapy, the conventional systemic agents for moderate-to-severe psoriasis, and the recommendation of biologic for retractable psoriasis to conventional systemic therapy and phototherapy. Conclusion: This modified Delphi panel established an expert consensus on the therapeutic approach for Korean patients with plaque psoriasis. This consensus may improve the treat- ment outcomes for psoriasis in Korea.

참고문헌 (45)

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Comparison of Treatment Goals for Moderate-to-Severe Psoriasis between Korean Dermatologists and the European Consensus Report김광중, 김낙인, 김보리, 송해준, 윤상웅, 윤재일, 이주흥, 최용범, 최지호대한피부과학회 · Annals of Dermatology2015 · 제27권 제2호Real-World Experience with Etanercept Therapy and the Switching Pattern among Korean Patients with Psoriasis after Withdrawal of Etanercept김보리, 유다애, 윤상웅, 이지수, 최종원대한피부과학회 · Annals of Dermatology2019 · 제31권 제1호Adherence to Topical Therapies for the Treatment of Psoriasis: Surveys of Physicians and Patients김보리, 윤상웅, 최지웅대한피부과학회 · Annals of Dermatology2017 · 제29권 제5호Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): Basic Therapy, Topical Therapy, and Conventional Systemic Therapy고주연, 고현창, 나찬호, 서영준, 신민경, 안지영, 유박린, 이동훈, 이상은, 이설희, 장용현, 전지현, 한태영, Bae Youin, Choi Sun Young, Cho Sang Hyun, Han Ju Hee, Kim Hye One, Lee Ji Hyun, Lee Yang Won, Son Sang Wook, Woo Yu Ri대한피부과학회 · Annals of Dermatology2025 · 제37권 제4호Clinical Characteristics of Psoriasis for Initiation of Biologic Therapy: A Cluster Analysis김승일, 김율희, 박범희, 이은소대한피부과학회 · Annals of Dermatology2023 · 제35권 제2호건선의 치료 접근법에 대한 고찰 및 제언강동원, 김규석, 김윤범, 김준동, 한창이대한한방안이비인후피부과학회 · 한방안이비인후피부과학회지2020 · 제33권 제3호

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