한림 뇌졸중 등록 자료를 통한 1,129명의 급성 뇌졸중 환자의 임상 양상

Abstract

Background and Objectives : Stroke is a leading cause of death in Korea. To better understand clinical patterns, risk factors and subtypes of acute stroke, the data of Hallym Stroke Registry were analyzed and compared with the results from other stroke data bank. Methods : A prospective hospital-based registry using systematic computerized data of all consecutive acute stroke patients admitted to Hallym stroke center and three affiliated hospitals has been conducted since Jan. 1993, and it included 1,129 cases with acute stroke. We analyzed demographic features, time delayed before visiting hospital after the onset of symptom, duration of admission, risk factors and the 30-day mortality rate. Stroke subtypes was categorized as large-artery atherosclerosis(LAA), small-vessel occlusion(SVO), cardioembolism(CE), stroke of other determined etiology(SOE), stroke of undetermined etiology(SUE). Results : One thousand and eighteen patients(m:f=1:0.73, mean age 63.7¡¾12.) had ischemic stroke and 111 patients(3m:f=1:1.22, mean age 61.0¡¾12.6) had cerebral hemorrhage on brain CT scan or MR imaging. The interval between the onset of symptom and hospital admission was 2.7 days in average and the mean duration of admission was 20.5 days. Among risk factors of ischemic stroke, hypertension(61.4%) was most frequent, followed by hyperlipidemia(50.7%), smoking(33.7%), previous history of stroke(32.5%), diabetes mellitus(26.4%), and cardiac embolic source(15.9%). The carotid territory was involved in 62.9% and the vertebrobasilar territory in 32.7%. SVO was the most frequent subtype(37.0%) of ischemic stroke, followed by LAA(35.4%), SUE(15.2%). CE(10.4%), and SOE(2.0%) in this study. The 30-day mortality rate of 651 patients with acute ischemic stroke between Jan. 1993 and Dec. 1996 was 7.7%. Conclusion : The proportion of stroke subtypes varied in different registries. It may be partly due to the different classification criteria and racial-ethnic differences. This registry provides with risk factors, etiology and clinical features and may afford further insights on the characteristics of Korean stroke patients. Korean Journal of Stroke 1999;1(1):21~27