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KERD
논문KCI 등재

기능성 식도장애

Functional Esophageal Disorders

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참고문헌

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주제분류재활의학

초록

Functional esophageal disorders represent processes accompanied by typical esophageal symptoms (heartburn, chest pain, dysphagia, globus) that have no readily identified structural disorders, gastroesophageal reflux disease (GERD), histopathology-based esophageal motor disturbances. GERD is the preferred diagnosis when reflux esophagitis or pathologic acid exposure is present or when typical symptoms are closely related to acid reflux or respond to proton pump inhibitor (PPI) test. A well-defined pathogenetic mechanism is unavailable for any of these disorders; combinations of sensory and motor abnormalities involving both central and peripheral are. Treatments remain empirical and management approaches that modulate central symptom perception or amplification often are required. (JKDS 2011;1:67-71)

Abstract

Functional esophageal disorders represent processes accompanied by typical esophageal symptoms (heartburn, chest pain, dysphagia, globus) that have no readily identified structural disorders, gastroesophageal reflux disease (GERD), histopathology-based esophageal motor disturbances. GERD is the preferred diagnosis when reflux esophagitis or pathologic acid exposure is present or when typical symptoms are closely related to acid reflux or respond to proton pump inhibitor (PPI) test. A well-defined pathogenetic mechanism is unavailable for any of these disorders; combinations of sensory and motor abnormalities involving both central and peripheral are. Treatments remain empirical and management approaches that modulate central symptom perception or amplification often are required. (JKDS 2011;1:67-71)

참고문헌 (13)

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  3. Galmiche JP, "Functional esophageal disorders", Gastroenterology, 130, pp.1459~1465 (2006)
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  7. 김정환, "한국의 비심인성 흉통의 진단 및 치료의 고유한 특징", 대한내과학회지, 80(6), pp.649~655 (2011), 대한내과학회
  8. Kim JH, "Clinical usefulness of subgrouping of patients with non-cardiac chest pain according to characteristic symptoms in Korea", J Gastroenterol Hepatol, 22, pp.320~325 (2007)
  9. Fass R, "The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain", Gastroenterology, 115, pp.42~49 (1998)
  10. Kim JH, "Comparison of one-week and two-week empirical trial with a high-dose rabeprazole in non-cardiac chest pain patients", J Gastroenterol Hepatol, 24, pp.1504~1509 (2009)
  11. Drossman DA, "U.S. householders survey of functional gastrointestinal disorders. Prevalen ce, sociodemography and health impact", Dig Dis Sci, 38, pp.1569~1580 (1993)
  12. Timon C, "Globus pharyngeus : long-term follow-up and prognostic factors", Ann Otol Rhinol Laryngol, 100, pp.351~354 (1991)
  13. Sinn DH, "Response rate and predictors of response in a short-term empirical trial of high-dose rabeparazole in patients with globus", Aliment Pharmacol Ther, 27, pp.1275~1281 (2008)

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