본문 바로가기
KERD
논문KCI 등재

항암화학요법을 받는 대장암 환자의 증상경험과 삶의 질

Symptom Experience and Quality of Life in Colorectal Cancer Patients Undergoing Chemotherapy

1

조회

0

다운로드

5

인용

0

참고문헌

키워드

주제분류간호학

초록

Purpose: This study aimed to evaluate symptom experience and quality of life (QoL) and to identify the predictors of QoL among colorectal cancer patients undergoing chemotherapy. Methods: A cross-sectional study was conducted on 107 colorectal cancer patients at a university-affiliated hospital between June 1 and July 30, 2021. Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Memorial Symptom Assessment Scale-Short Form (MSAS-SF) were used to assess symptom experience and QoL of these patients. Data were analyzed using Pearson’s correlation, t-test, ANOVA, and hierarchical multiple regression. Results: The mean QoL score for colorectal cancer patients was 88.78±20.08. The most frequently experienced physical and psychological symptoms were numbness/tingling and worrying. Physical and psychological symptoms have a significant negative association with QoL. Perceived economic status was significantly associated with QoL in patients’ general characteristics. The regression analyses showed that high psychological symptoms (β=-.63, p<.001), middle perceived economic status (β=-.22, p=.009) and low perceived economic status (β=-.36, p<.001) were statistically significant in predicting patients’ low QoL. Conclusion: Symptom experience and QoL are essential variables that should be acknowledged when delivering health care to colorectal cancer patients. More attention to the reduction and comprehensive symptom management of psychological distress could improve QoL among colorectal cancer patients.

Abstract

Purpose: This study aimed to evaluate symptom experience and quality of life (QoL) and to identify the predictors of QoL among colorectal cancer patients undergoing chemotherapy. Methods: A cross-sectional study was conducted on 107 colorectal cancer patients at a university-affiliated hospital between June 1 and July 30, 2021. Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Memorial Symptom Assessment Scale-Short Form (MSAS-SF) were used to assess symptom experience and QoL of these patients. Data were analyzed using Pearson’s correlation, t-test, ANOVA, and hierarchical multiple regression. Results: The mean QoL score for colorectal cancer patients was 88.78±20.08. The most frequently experienced physical and psychological symptoms were numbness/tingling and worrying. Physical and psychological symptoms have a significant negative association with QoL. Perceived economic status was significantly associated with QoL in patients’ general characteristics. The regression analyses showed that high psychological symptoms (β=-.63, p<.001), middle perceived economic status (β=-.22, p=.009) and low perceived economic status (β=-.36, p<.001) were statistically significant in predicting patients’ low QoL. Conclusion: Symptom experience and QoL are essential variables that should be acknowledged when delivering health care to colorectal cancer patients. More attention to the reduction and comprehensive symptom management of psychological distress could improve QoL among colorectal cancer patients.

참고문헌 (30)

  1. "Annual report of cancer statistics in Korean 2019"[URL]
  2. Benson AB 3rd, "Rectal cancer, version 2. 2018, NCCN clinical practice guidelines in oncology", J Natl Compr Canc Netw, 16, pp.874~901 (2018)
  3. Han CJ, "Symptom experiences in colorectal cancer survivors after cancer treatments : a systematic review and meta-analysis", Cancer Nurs, 43, pp.E132~E158 (2020)
  4. Cella DF, "Quality of life in cancer : definition, purpose, and method of measurement", Cancer Invest, 11, pp.327~336 (1993)
  5. AlFayyad I, "Health-related quality of life of breast and colorectal cancer patients undergoing active chemotherapy treatment : Patient-reported outcomes", Qual Life Res, 31, pp.2673~2680 (2022)
  6. André T, "Three versus 6 months of oxaliplatin-based adjuvant chemotherapy for patients with stage III colon cancer: disease-free survival results from a randomized, open-label, international duration evaluation of adjuvant (IDEA) France, phase III trial", J Clin Oncol, 36, pp.1469~1477 (2018)
  7. Lu LC, "Daily activity, mood, and quality of life in colorectal cancer patients with chemotherapy-induced peripheral neuropathy : a mediation effect analysis", Cancer Med, 8, pp.963~971 (2019)
  8. Soveri LM, "Long-term neuropathy and quality of life in colorectal cancer patients treated with oxaliplatin containing adjuvant chemotherapy", Acta Oncol, 58, pp.398~406 (2019)
  9. Goździewicz B, "Functioning of people with colorectal cancer during chemotherapy. Demographic and clinical determinants of quality of life of patients with colorectal cancer receiving chemotherapy. Pilot study", Eur J Cancer Care (Engl), 26, pp.e12616~ (2017)
  10. Röhrl K, "High symptom burden is associated with impaired quality of life in colorectal cancer patients during chemotherapy : a prospective longitudinal study", Eur J Oncol Nurs, 44, pp.101679~ (2020)
  11. Röhrl K, "Symptoms during chemotherapy in colorectal cancer patients", Support Care Cancer, 27, pp.3007~3017 (2019)
  12. Meng X, "Impact of non-pharmacological interventions on quality of life, anxiety, and depression scores in patients with colorectal cancer : a systematic review and meta-analysis of randomized controlled trials", Support Care Cancer, 29, pp.5635~5652 (2021)
  13. 최경숙, "대장암 환자의 증상경험과 극복력이 삶의 질에 미치는 효과", Asian Oncology Nursing, 12(1), pp.61~68 (2012), 대한종양간호학회
  14. 김은희, "항암화학요법을 받은 대장암환자의 증상, 피로 및 삶의 질의 종단적 경로분석", 보건정보통계학회지, 43(3), pp.200~207 (2018), 한국보건정보통계학회[DOI]
  15. Taghizadeh A, "Psychological distress in cancer patients", Middle East J Cancer, 9, pp.143~149 (2018)
  16. Schuurhuizen CS, "Does severe toxicity affect global quality of life in patients with metastatic colorectal cancer during palliative systemic treatment? A systematic review", Ann Oncol, 28, pp.478~486 (2017)
  17. Chang VT, "The memorial symptom assessment scale short form (MSAS-SF)", Cancer, 89, pp.1162~1171 (2000)
  18. Nho JH, "Reliability and validity of the Korean Memorial Symptom Assessment Scale-Short Form in gynecological cancer patients", J Pain Symptom Manage, 55, pp.101~107 (2018)
  19. Lam WW, "New insights in symptom assessment: the Chinese Versions of the Memorial Symptom Assessment Scale Short Form (MSAS-SF) and the Condensed MSAS (CMSAS)", J Pain Symptom Manage, 36, pp.584~595 (2008)
  20. Ward WL, "Reliability and validity of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) quality of life instrument", Qual Life Res, 8, pp.181~195 (1999)
  21. Lewis C, "Effects of adjuvant chemotherapy on recurrence, survival, and quality of life in stage II colon cancer patients : a 24-month follow-up", Support Care Cancer, 24, pp.1463~1471 (2016)
  22. Tang H, "The health-related quality of life changes following surgery in patients with colorectal cancer : a longitudinal study", ANZ J Surg, 92, pp.1461~1465 (2022)
  23. Tantoy IY, "Changes in the occurrence, severity, and distress of symptoms in patients with gastrointestinal cancers receiving chemotherapy", J Pain Symptom Manage, 55, pp.808~834 (2018)
  24. Hofsø K, "Changes over time in occurrence, severity, and distress of common symptoms during and after radiation therapy for breast cancer", J Pain Symptom Manage, 45, pp.980~1006 (2013)
  25. 김혜경, "Factors Influencing Supportive Care Needs of Colorectal Cancer Survivors", Asian Nursing Research, 15(1), pp.60~66 (2021), 한국간호과학회[DOI]
  26. Mols F, "Symptoms of anxiety and depression among colorectal cancer survivors from the population-based, longitudinal PROFILES Registry: prevalence, predictors, and impact on quality of life", Cancer, 124, pp.2621~2628 (2018)
  27. Drury A, "Identifying associations between quality of life outcomes and healthcare-related variables among colorectal cancer survivors: a cross-sectional survey study", Int J Nurs Stud, 101, pp.103434~ (2020)
  28. Trudel-Fitzgerald C, "Psychological symptoms and subsequent healthy lifestyle after a colorectal cancer diagnosis", Health Psychol, 37, pp.207~217 (2018)
  29. Son H, "Effect of psychosocial interventions on the quality of life of patients with colorectal cancer : a systematic review and meta-analysis", Health Qual Life Outcomes, 16, pp.119~ (2018)
  30. Sharp L, "Financial Impact of colorectal cancer and its consequences : associations between cancer-related financial stress and strain and health-related quality of life", Dis Colon Rectum, 61, pp.27~35 (2018)

관련 논문AI추천

이 간행물의 다른 논문 (6건)