본문 바로가기
KERD
논문KCI 등재

Relationship between Obesity and UTI in Children Under 2 Years of Age Admitted with Fever

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류소아과학

초록

Purpose: We observed an association between obesity and UTI in infants and pediatric patients, which we aimed to validate in this study. Method: The medical records of 740 patients (≤24 months old) hospitalized with fever were retrospectively analyzed. The patients were subdivided into 2 groups, namely, the UTI and control (non UTI) groups. We analyzed the patient’s height, weight. Obesity was defined as weight-for-length ≥95th percentile, and the association between obesity and UTI was evaluated. Results: Out of 740 patients, 253 and 487 patients were in the UTI group and the control group, respectively. A comparative analysis, based on 3 age groups (0–5 months, 6–11 months, and 12–24 months) showed higher proportion of obesity in the UTI group (26.4%) than in the control group (13.0%) in the 0-5months group. After adjusting for age and gender in the 0-5month group, the obesity group was 3.76 times likely to have an UTI (95% CI 1.419–9.98). Conclusion: Obesity and UTI show strong association, especially in infants aged 0-5 months. Febrile obese infant patients (≤5 months old) visiting medical centers should be advised urine tests for potential UTI.

Abstract

Purpose: We observed an association between obesity and UTI in infants and pediatric patients, which we aimed to validate in this study. Method: The medical records of 740 patients (≤24 months old) hospitalized with fever were retrospectively analyzed. The patients were subdivided into 2 groups, namely, the UTI and control (non UTI) groups. We analyzed the patient’s height, weight. Obesity was defined as weight-for-length ≥95th percentile, and the association between obesity and UTI was evaluated. Results: Out of 740 patients, 253 and 487 patients were in the UTI group and the control group, respectively. A comparative analysis, based on 3 age groups (0–5 months, 6–11 months, and 12–24 months) showed higher proportion of obesity in the UTI group (26.4%) than in the control group (13.0%) in the 0-5months group. After adjusting for age and gender in the 0-5month group, the obesity group was 3.76 times likely to have an UTI (95% CI 1.419–9.98). Conclusion: Obesity and UTI show strong association, especially in infants aged 0-5 months. Febrile obese infant patients (≤5 months old) visiting medical centers should be advised urine tests for potential UTI.

참고문헌 (21)

  1. Hudson A, "Urinary tract infection in children", CMAJ, 189, pp.E608~ (2017)[DOI]
  2. Robert K, "Nelson text of pediatrics 20th edition", Science Health Science, pp.1280~1287 (2016)
  3. Stokland E, "Renal damage one year after first urinary tract infection: role of dimercaptosuccinic acid scintigraphy", J Pediatr, 129, pp.815~820 (1996)[DOI]
  4. 김유빈, "Is vaginal reflux associated with urinary tract infection in female children under the age of 36 months?", Clinical and Experimental Pediatrics, 61(1), pp.17~23 (2018), 대한소아청소년과학회
  5. Ellis D. Avner, "Pediatric Nephrology", pp.1007~1025 (2009), Springer Berlin Heidelberg
  6. Mydlo JH, "The impact of obesity in urology", Urol Clin North Am, 31, pp.275~287 (2004)[DOI]
  7. Yang TH, "Obesity and a febrile urinary tract infection: Dual burden for young children?", Urology, 84, pp.445~449 (2014)[DOI]
  8. McCormick DP, "Infant obesity: are we ready to make this diagnosis?", J Pediatr, 157, pp.15~19 (2010)[DOI]
  9. Dietz WH, "The obesity epidemic in young children. Reduce television viewing and promote playing", BMJ, 322, pp.313~314 (2001)[DOI]
  10. Twells L, "Can exclusive breastfeeding reduce the likelihood of childhood obesity in some regions of Canada?", Can J Public Health, 101, pp.36~39 (2010)
  11. Oddy WH, "Infant feeding and obesity risk in the child", Breastfeed Rev, 20, pp.7~12 (2012)
  12. Newburg DS, "Characteristics and potential functions of human milk adiponectin", J Pediatr, 156, pp.41~46 (2010)[DOI]
  13. Semins MJ, "The impact of obesity on urinary tract infection risk", Urology, 79, pp.266~269 (2012)
  14. Cooper CS, "Infection and inflammation of the pediatric genitourinary tract. Campbell-Walsh Urology", pp.2926~ (2016), Elsevier
  15. Spencer JD, "The innate immune response during urinary tract infection and pyelonephritis", Pediatr Nephrol, 29, pp.1139~1149 (2014)[DOI]
  16. Grier WR, "Obesity as a Risk Factor for Urinary Tract Infection in Children", Clin Pediatr, 55, pp.952~956 (2016)[DOI]
  17. Yim HE, "Overweight, hypertension and renal dysfunction in adulthood of neonatally overfed rats", J Nutr Biochem, 24, pp.1324~1333 (2013)[DOI]
  18. Yim HE, "Postnatal early over nutrition causes long-term renal decline in aging male rats", Pediatr Res, 7, pp.259~265 (2014)
  19. Ajetunmobi OM, "Breastfeeding is associated with reduced childhood hospitalization: evidence from a Scottish Birth Cohort (1997-2009)", J Pediatr, 166, pp.620~625 (2015)[DOI]
  20. Blewett HJH, "The immunological components of human milk", Adv Food Nutr, 54, pp.45~80 (2018)
  21. Hanson LA, "The transfer of immunity from mother to child", Ann NY Acad Sci, 987, pp.199~206 (2010)

관련 논문AI추천

이 간행물의 다른 논문 (11건)