Successful treatment of solar lentigines using a novel 532-nm nanosecond neodymium-doped yttrium aluminum garnet vasculature salvage laser surgery system: case series

Abstract

Solar lentigines are benign pigmented lesions commonly treated with 532-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, though outcomes can be limited by post-inflammatory hyperpigmentation (PIH), especially in darker skin types. This case series evaluated a novel 532-nm nanosecond Nd:YAG vasculature salvage laser surgery (VSLS) system, designed to minimize PIH risk through two key features: cryo-photothermolysis, which induces vasoconstriction to reduce hemoglobin absorption, and AutoDerm®, which enables precise lesion targeting. Two female patients in their 60s with persistent solar lentigines, unresponsive to prior laser treatments, underwent a single VSLS session. Complete resolution of the lentigines was achieved after one treatment session, with no signs of PIH, prolonged erythema, or scarring observed throughout 3 months of follow-up. This outcome suggests the VSLS system may offer a safer and more effective alternative for treating solar lentigines, particularly in patients at a higher risk of laser-induced complications.