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정상인과 녹내장 환자에서 수술 전 안구 계측치와 백내장 수술 후 안압 하강과의 관계

Relationship between Preoperative Biometry and Intraocular Pressure Reduction after Phacoemulsification in Normal and Glaucoma Patients

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초록

목적: 정상군과 녹내장군에서 수술 전 인자가 백내장 수술 후 안압하강 정도를 예측하는데 도움이 되는지를 알아보고자 하였다. 대상과 방법: 정상군 30명, 개방각녹내장군 24명, 폐쇄각녹내장군 31명을 대상으로 수술 전과 수술 후 3개월의 안압을 측정하였다. 각군별로 수술 전 안압, 전방 깊이, 안축장 길이, 수술 전 안압을 전방 깊이로 나눈 Pressure/Depth ratio (PD ratio), 수술 전 안압을안축장으로 나눈 Pressure/Length ratio (PL ratio)와 안압하강 정도와의 관계를 분석하였다. 결과: 안압하강 정도와 수술 전 안압은 세 군에서 모두 유의한 상관관계를 보였다(p<0.001). PD ratio는 개방각녹내장군에서만 안압하강 정도와 유의한 상관관계를 보였으나(p<0.001) PL ratio는 세 군 모두에서 유의한 상관관계를 보였고(p<0.05), 술 후 안압하강을예측하는 데 PL ratio가 PD ratio보다 나은 민감도와 특이도를 보였다. 결론: PL ratio는 백내장수술 후 안압하강을 예측하는 데 유용한 지표이며, 다른 대상군에 비해 개방각녹내장군에서의 예측력이 더좋은 경향을 보였다.

Abstract

Purpose: To investigate the relationships between preoperative factors and intraocular pressure (IOP) reduction after phacoemulsification in normal, open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) patients. Methods: IOP was measured before and 3 months after cataract surgery in 30 normal, 24 OAG and 31 ACG patients. The relationship between IOP reduction after cataract surgery and preoperative parameters including anterior chamber depth (ACD), axial length (AL), preoperative IOP/ACD ratio (PD ratio), preoperative IOP/AL ratio (PL ratio) were investigated in the 3 groups. Results: Significant IOP reduction was observed in all 3 groups after surgery (paired sample t-test; p < 0.05), and IOP reduction was correlated with preoperative IOP level in all 3 groups (Pearson’s correlation; p < 0.05). Other preoperative parameters such as ACD and AL were not correlated with IOP reduction, and PD ratio was significantly correlated with IOP reduction only in the OAG group (Pearson’s correlation; p < 0.001). PL ratio was significantly correlated with IOP reduction in all 3 groups (Pearson’s correlation; p < 0.05) and showed the best sensitivity and specificity to predict significant reduction in IOP after cataract surgery among parameters including preoperative IOP, PD ratio and PL ratio. Conclusions: PL ratio was significantly correlated with IOP reduction after cataract surgery in all 3 groups and showed a higher predictive value for IOP reduction in the OAG group than in the other groups.

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