Trends and Characteristics of Mortality Associated with Congenital Anomalies in Korean Children under 5 Years of Age
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Purpose: Studies have been conducted on the prevalence and infant mortality rate of congenital anomalies; however, studies on child mortality are rare. Therefore, we evaluated the characteristics of deaths associated with congenital anomalies among children born in Korea who died within 5 years of age. Methods: Birth-to-death cohort linked data of children under the age of 5 years from 2010 to 2013, and statistical data on the cause of death by age from 1999 to 2019, both provided by the Korea National Statistical Office's Microdata Integrated Service, were retrospectively investigated. We investigated the trends and characteristics of mortality associated with congenital anomalies. Results: Among 1,858,945 children, 6,510 children who died were under 5 years of age, and among them, 1,229 deaths were associated with congenital anomalies, while 5,281 deaths were due to other causes. Deaths associated with congenital anomalies accounted for 18.9% of all deaths. When comparing congenital anomalies by systems, anomalies of the cardiovascular system (52.6%) were the most common. The mortality rate associated with congenital anomalies and those of other causes showed similar declining trends in 21 years. Conclusion: The mortality rate of congenital anomalies during the first 5 years of life did not increase differently from the prevalence of congenital anomalies but rather decreased. Deaths associated with congenital anomalies accounted for 20.5% of all infant deaths and 12.1% of child deaths, since the major causes of death in infants and children are slightly different, continuous and careful monitoring is required.
Abstract
Purpose: Studies have been conducted on the prevalence and infant mortality rate of congenital anomalies; however, studies on child mortality are rare. Therefore, we evaluated the characteristics of deaths associated with congenital anomalies among children born in Korea who died within 5 years of age. Methods: Birth-to-death cohort linked data of children under the age of 5 years from 2010 to 2013, and statistical data on the cause of death by age from 1999 to 2019, both provided by the Korea National Statistical Office's Microdata Integrated Service, were retrospectively investigated. We investigated the trends and characteristics of mortality associated with congenital anomalies. Results: Among 1,858,945 children, 6,510 children who died were under 5 years of age, and among them, 1,229 deaths were associated with congenital anomalies, while 5,281 deaths were due to other causes. Deaths associated with congenital anomalies accounted for 18.9% of all deaths. When comparing congenital anomalies by systems, anomalies of the cardiovascular system (52.6%) were the most common. The mortality rate associated with congenital anomalies and those of other causes showed similar declining trends in 21 years. Conclusion: The mortality rate of congenital anomalies during the first 5 years of life did not increase differently from the prevalence of congenital anomalies but rather decreased. Deaths associated with congenital anomalies accounted for 20.5% of all infant deaths and 12.1% of child deaths, since the major causes of death in infants and children are slightly different, continuous and careful monitoring is required.
참고문헌 (16)
- 정성훈, "단일 신생아 중환자실에서 경험한 최근 10년간 선천성 기형의 변화", Perinatology, 24(1), pp.11~20 (2013), 대한주산의학회
- Tomatir AG, "Major congenital anomalies : a five-year retrospective regional study in Turkey", Genet Mol Res, 8, pp.19~27 (2009)
- Lamichhane DK, "Increased prevalence of some birth defects in Korea, 2009-2010", BMC Pregnancy Childbirth, 16, pp.61~ (2016)
- Congenital anomaly survey and statistics, "Choi JS", Korea Institute for Health and Social Affairs, ~, pp.Report No: 11-1351000-000517-12 (2009)
- "Leading causes of death and numbers of deaths, by age: United States, 1980 and 2016" (2021)[URL]
- Sung-Hoon Chung, "Changes in the neonatal and infant mortality rate and the causes of death in Korea", Clinical and Experimental Pediatrics, 54(11), pp.443~455 (2011), 대한소아청소년과학회
- Wen SW, "Regional patterns of infant mortality caused by lethal congenital anomalies", Can J Public Health, 90, pp.316~319 (1999)
- Rosano A, "Infant mortality and congenital anomalies from 1950 to 1994 : an international perspective", J Epidemiol Community Health, 54, pp.660~666 (2000)
- "The contribution of congenital anomalies to infant mortality" (2010)[URL]
- Nacher M, "High mortality due to congenital malformations in children aged < 1 year in French Guiana", BMC Pediatr, 18, pp.393~ (2018)
- Roncancio CP, "Trends and characteristics of fetal and neonatal mortality due to congenital anomalies, Colombia 1999-2008", J Matern Fetal Neonatal Med, 31, pp.1748~1755 (2018)
- 장민정, "Mortality Rate and Major Causes of Death by Gestational Age in Korean Children under 5 Years of Age", Journal of Korean Medical Science, 35(40), pp.1~14 (2020), 대한의학회[DOI]
- Singh K, "Major congenital malformations in Barbados: the prevalence, the pattern, and the resulting morbidity and mortality", ISRN Obstet Gynecol, 2014, pp.651783~ (2014)
- Lee K, "Infant mortality from congenital malformations in the United States, 1970-1997", Obstet Gynecol, 98, pp.620~627 (2001)
- Wang Y, "A retrospective cohort study of mortality among children with birth defects in New York State, 1983-2006", Birth Defects Res A Clin Mol Teratol, 88, pp.1023~1031 (2010)
- Boneva RS, "Mortality associated with congenital heart defects in the United States: trends and racial disparities, 1979-1997", Circulation, 103, pp.2376~2381 (2001)