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Analysis of the Use of Medical Institutions and Prescription Drugs for Pulmonary Tuberculosis in Geriatric Patients
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Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that can affect many organs of thebody but usually affects the lungs. The prevalence of TB in Korea is considerably higher than that in other countries with similareconomic levels, and is much higher in elderly people. Pharmacotherapy is important in the treatment of TB and requires relativelyhigh compliance for a prolonged duration. Methods: We analyzed sample data of elderly patients obtained from the HealthInsurance Review and Assessment Service. We used logistic regression analysis and frequency analysis to identify factors thatcould affect prevalence of TB in elderly patients, compliance with prescribed medication regimes in these patients, and use ofmedical institutions. Korean Standard Classification of Diseases, version 7 (KCD-7) was used to diagnose pulmonary TB, andmedications were analyzed using Korean standardized drug classification codes. Results: 1,276,331 patients were analyzed in thesample of the elderly population, and 16,658 TB patients were included in the study. The mean age of the TB patients was 76.19years (SD 6.899). A total of 699 patients were prescribed isoniazid, rifampicin, ethambutol, or pyrazinamide at least once. Of these,352 (50.4%) were prescribed all four medications and 101 (14.4%) were prescribed only isoniazid, rifampicin, and ethambutol. Themean duration of prescription was 28.75 days (SD 36.13). Conclusion: In the elderly population, old age and poor socioeconomicconditions correlated with TB prevalence. Most patients did not meet the criteria for effective pharmacotherapy of TB.
Abstract
Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that can affect many organs of thebody but usually affects the lungs. The prevalence of TB in Korea is considerably higher than that in other countries with similareconomic levels, and is much higher in elderly people. Pharmacotherapy is important in the treatment of TB and requires relativelyhigh compliance for a prolonged duration. Methods: We analyzed sample data of elderly patients obtained from the HealthInsurance Review and Assessment Service. We used logistic regression analysis and frequency analysis to identify factors thatcould affect prevalence of TB in elderly patients, compliance with prescribed medication regimes in these patients, and use ofmedical institutions. Korean Standard Classification of Diseases, version 7 (KCD-7) was used to diagnose pulmonary TB, andmedications were analyzed using Korean standardized drug classification codes. Results: 1,276,331 patients were analyzed in thesample of the elderly population, and 16,658 TB patients were included in the study. The mean age of the TB patients was 76.19years (SD 6.899). A total of 699 patients were prescribed isoniazid, rifampicin, ethambutol, or pyrazinamide at least once. Of these,352 (50.4%) were prescribed all four medications and 101 (14.4%) were prescribed only isoniazid, rifampicin, and ethambutol. Themean duration of prescription was 28.75 days (SD 36.13). Conclusion: In the elderly population, old age and poor socioeconomicconditions correlated with TB prevalence. Most patients did not meet the criteria for effective pharmacotherapy of TB.
참고문헌 (18)
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