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A Case of Cutaneous Mucormycosis Occurring after Systemic Steroid Therapy

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초록

Cutaneous mucormycosis is a rare disease caused by zygomycetes such as Rhizomucor, Mucor, Absidia, and Rhizopus. The disease usually occurs in immunocompromised individuals, and the organism is rarely pathogenic in an immunocompetent host. Herein, we report a 77-year-old female patient who had multiple erythematous papules and pustules on the left 3rd finger. She had received systemic steroid therapy prior to the occurrence of the skin lesions. The histopathological examination of Periodic Acid Schiff stained section showed chronic granulomatous inflammation and fungal hyphae. Rhizopus species was isolated on the fungal culture of the tissue specimen. The patient was finally diagnosed with cutaneous mucormycosis and was treated with itraconazole.

Abstract

Cutaneous mucormycosis is a rare disease caused by zygomycetes such as Rhizomucor, Mucor, Absidia, and Rhizopus. The disease usually occurs in immunocompromised individuals, and the organism is rarely pathogenic in an immunocompetent host. Herein, we report a 77-year-old female patient who had multiple erythematous papules and pustules on the left 3rd finger. She had received systemic steroid therapy prior to the occurrence of the skin lesions. The histopathological examination of Periodic Acid Schiff stained section showed chronic granulomatous inflammation and fungal hyphae. Rhizopus species was isolated on the fungal culture of the tissue specimen. The patient was finally diagnosed with cutaneous mucormycosis and was treated with itraconazole.

참고문헌 (19)

  1. Jang HS, "A case of Rhinocerebral mucormycosis in a diabetic woman", Ann Dermatol, 3, pp.145~152 (1991)
  2. 양정훈, "스포로트릭스증 양상을 보인 피부 모균증 1예", 대한피부과학회지, 48(5), pp.449~452 (2010), 대한피부과학회
  3. Tehmeena W, "Primary cutaneous mucormycosis in an immunocompetent host", Mycopathologia, 164, pp.197~199 (2007)
  4. Paltauf A, "Mycosis mucorina. Ein Beitrag zur Kenntniss der menshlichen Fadenpilzer Krankugen", Virchows Arch Pathol Anat, 102, pp.543~563 (1885)
  5. Ameen M, "The emergence of mucormycosis as an important opportunistic fungal infection:five cases presenting to a tertiary referral center for mycology", Int J Dermatol, 46, pp.380~384 (2007)
  6. Sutherland-Campbell H, "Paronychia:an attempt to prove the etiologic factor in an epidemic among orange workers", Arch Derm Syphilol, 19, pp.233~253 (1929)
  7. Wirth F, "Cutaneous mucormycosis with subsequent visceral dissemination in a child with neutropenia:A case report and review of the pediatric literature", J Am Acad Dermatol, 36, pp.336~341 (1997)
  8. Mandell GL, "Principles and practice of infectious diseases: agents of mucormycosis and related species", pp.2311~ (1995), Churchill Livingstone
  9. Chin RY, "Generation of chemotactic factors by Rhizopus oryzae in the presence and absence of serum: relationship to hyphal damage mediated by human neutrophils and effects of hyperglycemia and ketoacidosis", Infect Immun, 38, pp.1123~1129 (1982)
  10. Spellberg B, "Recent advances in the management of mucormycosis: from bench to bedside", Clin Infect Dis, 48, pp.1743~1751 (2009)
  11. Lee SH, "A case of cutaneous mucormycosis in a patient with acute lymphocytic leukemia", Korean J Dermatol, 27, pp.440~443 (1989)
  12. Choi YS, "A case of mucormycosis of skin and soft tissue in a healthy adult", Infection, 23, pp.55~59 (1991)
  13. Jo HY, "A case of primary cutaneous mucormycosis in a immunocompetent patient", Korean J Dermatol, 33, pp.546~550 (1995)
  14. Kim SY, "A case of cutaneous mucormycosis", Korean J Med Mycol, 3, pp.200~204 (1998)
  15. Lee HT, "A considered case as primary cutaneous mucormycosis", Korean J Med Mycol, 4, pp.75~78 (1999)
  16. Song WK, "Primary cutaneous mucormycosis associated with trauma", Korean J Dermatol, 38, pp.826~828 (2000)
  17. 서상희, "면역적격 노인에서 발생한 스포로트리쿰증양 분포를 보인 원발성 피부 모균증", 대한피부과학회지, 44(11), pp.1352~1356 (2006), 대한피부과학회
  18. 전재복, "Rhizopus arrhizus에 의한 만성 재발성 피부 모균증 1예", 대한의진균학회지, 13(1), pp.31~36 (2008), 대한의진균학회
  19. Kumar B, "Treatment of deep mycoses with itraconazole", Mycopathologia, 115, pp.169~174 (1991)

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