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12주 댄스스포츠 프로그램 참여가 FABP2 유전자형별 비만 및 인슐린저항성에 미치는 효과

Effect of a 12-week dancesport program on obesity and insulin resistance across the FABP2 genotype

강현식|한태경
한국운동생리학회|2007.05|운동과학 (Exercise Science)|제16권 제2호|pp. 103-114

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참고문헌

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비만댄스스포츠dancesportbody fatnessfasting glucoseFABP2 유전자형공복시혈당

초록

한태경. 강현식. 12주 댄스스포츠 프로그램 참여가 FABP2 유전자형별 비만 및 인슐린저항성에 미치는 효과. 운동과학, 제16권 제2호. 103-114, 2007. 이 연구의 목적은 FABP2 유전자형별 12주간 댄스스포츠 참여에 따른 중년여성의 비만지표와 인슐린저항성에 미치는 효과를 조사하는 것이다. 참여 피검자는 외관상 건강한 중년여성 94명(AA동형접합체 42명, AT이형접합체 41명, TT동형접합체 11명)으로 하였다. 12주간 댄스스포츠 프로그램은 50-60% VO2max로 1회 60분, 주당 3회 실시하였다. 프로그램 참여 사전·사후 신체구성변인과 심폐체력은 FABP2유전자형에 상관없이 유의하게 개선되었다. HDL-C와 공복시 혈당 그리고 경구당 부하검사에서 AUC는 FABP2유전자형에 상관없이 12주간 댄스스포츠 참여의 결과로서 유의하게 개선된 것으로 나타났으며, AA동형접합자와 TT동형접합자 집단보다 AT이형접합자 집단에서 수축기 혈압이 유의하게 높은 것으로 나타났다. 본 연구를 종합하면, 12주 댄스스포츠 프로그램 참여는 비만 중년여성의 비만지표, 심폐체력, 혈중 지질, 혈당을 유의하게 개선시키는데 효과적인 것으로 판단되는 반면 이러한 효과의 정도는 FABP2 유전자형에 따라 유의한 차이가 없는 것으로 밝혀졌다.

Abstract

Han, T.K., & Kang, H.S. Effect of a 12-week dancesport program on obesity and insulin resistance across the FABP2 genotype. Exercise Science, 16(2): 103-114, 2007. The purpose of this study was to investigate whether or not the FABP2 gene polymorphism modulated responses of the obesity & insulin resistance to 12 weeks of dancesport program in mid-life women. A total of 94 subjects (42 of A54A homozygotes, 41 of A54T heterozygotes, 11 of T54T homozygotes), who voluntarily participated in this study, underwent 12 weeks of dancesport program at an intensity of 50-60% VO2max with duration of 60 minutes per session and frequency of 3 days/week. Only significant time effects were found in changed scores of body fatness and fitness, HDL-C, fasting glucose, and glucose-AUC such that regardless of the FABP2 genotype, participating into the 12 weeks dancesport was effective in improving those dependent variables. Therefore, the current findings of the study suggest that the FABP2 Ala54Thr gene polymorphism may not modulate responses of the obesity & insulin resistance to exercise training in this study population.

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