이비인후과 영역에서의 보툴리눔 독소의 활용
The Clinical Utility of Botulinum Toxin in the Field of Otolaryngology
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초록
Botulinum toxin, originally identified in relation to botulism, has evolved from being consid-ered a perilous pathogen to an invaluable therapeutic agent. First utilized by Alan Scott in 1977to treat strabismus under the commercial name, Oculinum, the toxin received Food and DrugAdministration approval in 1989 and was subsequently rebranded as Botox. Its clinical appli-cations have expanded notably, especially in the field of otolaryngology, proving effective inmanaging conditions such as spasmodic dysphonia, essential vocal tremor, and chronic sali-vary gland disorders. Moreover, botulinum toxin has shown promising results in treating per-sistent chronic rhinitis, objective tinnitus, and synkinesis following facial palsy, significantlyimproving involuntary facial movements. This paper details the diverse applications andmethodologies of botulinum toxin across various ENT disorders, illustrating its growingscope and significance in medical practice.
Abstract
Botulinum toxin, originally identified in relation to botulism, has evolved from being consid-ered a perilous pathogen to an invaluable therapeutic agent. First utilized by Alan Scott in 1977to treat strabismus under the commercial name, Oculinum, the toxin received Food and DrugAdministration approval in 1989 and was subsequently rebranded as Botox. Its clinical appli-cations have expanded notably, especially in the field of otolaryngology, proving effective inmanaging conditions such as spasmodic dysphonia, essential vocal tremor, and chronic sali-vary gland disorders. Moreover, botulinum toxin has shown promising results in treating per-sistent chronic rhinitis, objective tinnitus, and synkinesis following facial palsy, significantlyimproving involuntary facial movements. This paper details the diverse applications andmethodologies of botulinum toxin across various ENT disorders, illustrating its growingscope and significance in medical practice.
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