Cross-Correlation Analysis of the Incidence of Multidrug-Resistant Organisms with Hand Hygiene Compliance and Effectiveness of Alcohol-Gel Hand Hygiene Practice
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Background: Multidrug- resistant organisms (MDRO) are a serious concern in healthcareassociated infections. Hand hygiene (HH) is essential to prevent the spread of MDRO in the healthcare institutes. The aim of this study was to investigate the relationship between the incidence of MDRO and hand hygiene compliance and the experimental effectiveness of alcohol-gel hand hygiene practice. Methods: From March 2016 to September 2018, we analyzed the cross-correlation between the incidence of MDRO and the HH compliance each month at Gyeongsang National University Changwon Hospital. We employed an experiment to observe the effect of alcohol gel hand hygiene practice on the reduction of organisms on the hand surface using the handagar plates. Results: Among the MDRO, only vancomycin-resistant enterococci (VRE) showed a moderate correlation with the HH rate (r = 0.55). The hand-agar plate experiment showed a significant bacterial reduction for inadequate HH (mean 3.47 CFU) and optimal HH (mean, 0.84 CFU) than before HH (mean, 11.56 CFU) (n = 32, P = 0.006). Conclusion: The incidence of VRE showed a moderate correlation with HH among MDRO in the longitudinal analysis. HH practice was more effective in preventing the spread of VRE compared with other MDRO in our institute. Optimal alcohol-gel HH practice can effectively remove bacteria on the hand surface.
Abstract
Background: Multidrug- resistant organisms (MDRO) are a serious concern in healthcareassociated infections. Hand hygiene (HH) is essential to prevent the spread of MDRO in the healthcare institutes. The aim of this study was to investigate the relationship between the incidence of MDRO and hand hygiene compliance and the experimental effectiveness of alcohol-gel hand hygiene practice. Methods: From March 2016 to September 2018, we analyzed the cross-correlation between the incidence of MDRO and the HH compliance each month at Gyeongsang National University Changwon Hospital. We employed an experiment to observe the effect of alcohol gel hand hygiene practice on the reduction of organisms on the hand surface using the handagar plates. Results: Among the MDRO, only vancomycin-resistant enterococci (VRE) showed a moderate correlation with the HH rate (r = 0.55). The hand-agar plate experiment showed a significant bacterial reduction for inadequate HH (mean 3.47 CFU) and optimal HH (mean, 0.84 CFU) than before HH (mean, 11.56 CFU) (n = 32, P = 0.006). Conclusion: The incidence of VRE showed a moderate correlation with HH among MDRO in the longitudinal analysis. HH practice was more effective in preventing the spread of VRE compared with other MDRO in our institute. Optimal alcohol-gel HH practice can effectively remove bacteria on the hand surface.
참고문헌 (15)
- Suarez C, "A large sustained endemic outbreak of multiresistant Pseudomonas aeruginosa : a new epidemiological scenario for nosocomial acquisition", BMC Infect Dis, 11, pp.272~ (2011)
- Link T, "Guideline implementation : transmission-based precautions", AORN J, 110, pp.637~649 (2019)
- Pena C, "Epidemiology and successful control of a large outbreak due to Klebsiella pneumoniae producing extendedspectrum beta-lactamases", Antimicrob Agents Chemother, 42, pp.53~58 (1998)
- De Waele JJ, "Multidrug-resistant bacteria in ICU : fact or myth", Curr Opin Anaesthesiol, 33, pp.156~161 (2020)
- World Health Organization, "WHO guidelines on hand hygiene in health care: first global patient safety challenge clean care is safer care", World Health Organization, ~ (2009)
- Sickbert-Bennett EE, "Reduction of healthcare-associated infections by exceeding high compliance with hand hygiene practices", Emerg Infect Dis, 22, pp.1628~1630 (2016)
- Sax H, "'My five moments for hand hygiene': a user-centred design approach to understand, train, monitor and report hand hygiene", J Hosp Infect, 67, pp.9~21 (2007)
- Baek EH, "The difference in hand hygiene compliance rate between unit-based observers and trained observers for World Health Organization checklist and optimal hand hygiene", Int J Infect Dis, 90, pp.197~200 (2020)
- Clinical and Laboratory Standards Institute (CLSI), "Performance standards for antimicrobial susceptibility testing; 29th ed. CLSI supplement M100", ~ (2019)
- Marimuthu K, "The effect of improved hand hygiene on nosocomial MRSA control", Antimicrob Resist Infect Control, 3, pp.34~ (2014)
- Apisarnthanarak A, "A multifaceted intervention to reduce pandrug-resistant Acinetobacter baumannii colonization and infection in 3 intensive care units in a Thai tertiary care center : a 3-year study", Clin Infect Dis, 47, pp.760~767 (2008)
- Loftus RW, "The dynamics of Enterococcus transmission from bacterial reservoirs commonly encountered by anesthesia providers", Anesth Analg, 120, pp.827~836 (2015)
- Vaillant L, "Awareness among French healthcare workers of the transmission of multidrug resistant organisms : a large cross-sectional survey", Antimicrob Resist Infect Control, 8, pp.173~ (2019)
- Lingawi H, "Impact of educational intervention for hand hygiene on dental students' knowledge, attitude, and bacterial contamination level on hands", J Contemp Dent Pract, 18, pp.1164~1172 (2017)
- Jabeen K, "Persistence of Candida auris on latex and nitrile gloves with transmission to sterile urinary cathetersdouble dagger", Med Mycol, 58, pp.128~132 (2020)