각막 지형도를 이용한 각막 구면수차의 산출
Estimation of Corneal Spherical Aberration from Topography
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목적: 각막지형도 검사에서 제시해 주는 여러 가지 지표들을 이용해서 간단하게 각막 구면수차를 산출할 수 있는 공식을 유도해내고자하였다. 대상과 방법: 백내장 수술을 계획한 76명, 76안을 대상으로 후향적으로 의무기록 검토를 통해 연구를 진행하였다. 평균 연령은 57.37± 17.63세였다. 각막 지형도 검사 Orbscan (Bausch & Lomb, Rochester, NY, USA)과 KR-1W (Topcon Corp, Tokyo, Japan) 두가지 검사를 시행하였으며, 각막지형도 검사 지표들을 독립변수로, KR-1W의 6 mm 동공에서의 각막 구면수차를 종속변수로 설정하여상관분석을 시행하였다. 상관분석 결과 유의하게 판정된 지표들을 이용하여 다중선형회귀분석을 시행하였다. 결과: KR-1W를 이용하여 측정한 대상 환자들의 평균 각막구면수차는 0.25 ± 0.08 μm였다. 다중선형회귀분석 결과 유도된 공식은Q-value를 포함할 경우에는 예측 각막구면수차=0.389×Q-value+(0.022×Axial power 3 mm)-0.633 (R2=0.436)였으며, Q-value를포함하지 않을 경우 예측 각막 구면수차=0.184×(Mean power 5 mm–Mean power 3 mm)+(0.02×Axial power 3 mm)-0.563(R2=0.429)였다. 유도된 공식을 활용하여 오차 범위 0.1 μm 내에서 약 93.4-94.7%를 예측할 수 있었다. 결론: 각막 구면수차 값을 제시하여 주는 별도의 수차계 없이 Orbscan만 갖춘 환경에서 본 공식을 활용하면 환자의 각막 구면 수차에따라 적절한 비구면 인공수정체를 선택하는 데 도움을 받을 수 있을 것이다.
Abstract
Purpose: To formulate an equation to estimate corneal spherical aberration using Orbscan (Bausch & Lomb Surgical,Rochester, NY, USA) parameters. Methods: The study was carried out retrospectively. The participants were 76 eyes of 76 senile cataract patients with the mean age of 57.37 ± 17.63 years. Both Orbscan and KR-1W (Topcon Corp, Tokyo, Japan) were taken as preoperative examinations. Correlation analysis between various parameters from Orbscan and corneal spherical aberrations for a 6mm pupil by KR-1W was performed. And multivariable linear regression was performed with the significantly correlated Orbscan parameters from the correlation analysis. Results: The mean corneal spherical aberration from KR-1W system was 0.25 ± 0.08 μm. As a result of the multivariable linear regression, we could generate following equations. If the Q-value was available, estimated corneal spherical aberration = 0.389 × Q-value + (0.022 × Axial power 3 mm) - 0.633 (R2 = 0.436). If the Q-value was not available, estimated corneal spherical aberration = 0.184 × (Mean power 5 mm – Mean power 3 mm) + (0.02 × Axial power 3 mm) - 0.563 (R2 =0.429). By using the equations, 93.4-94.7% of subjects were in the error range of 0.10 μm. Conclusions: Even when equipped with Orbscan only, an appropriate aspheric intraocular lens can be selected using the estimated corneal apherical aberration by the equations.
참고문헌 (12)
- Trueb PR, "Visual acuity and contrast sensitivity in eyes implanted with aspheric and spherical intraocular lenses", Ophthalmology, 116, pp.890~895 (2009)
- Pepose JS, "Comparison of contrast sensitivity, depth of field and ocular wavefront aberrations in eyes with an IOL with zero versus positive spherical aberration", Graefes Arch Clin Exp Ophthalmol, 247, pp.965~973 (2009)
- 김홍석, "비구면 인공수정체와 구면 인공수정체의 술 후 구면수차, 고위수차 및 대비감도의 비교", 대한안과학회지, 49(8), pp.1256~1262 (2008), 대한안과학회
- Caporossi A, "Prospective randomized study of clinical performance of 3 aspheric and 2 spherical intraocular lenses in 250 eyes", J Refract Surg, 23, pp.639~648 (2007)
- Rocha KM, "Wavefront analysis and contrast sensitivity of aspheric and spherical intraocular lenses: a randomized prospective study", Am J Ophthalmol, 142, pp.750~756 (2006)
- Beiko GH, "Distribution of corneal spherical aberration in a comprehensive ophthalmology practice and whether keratometry can predict aberration values", J Cataract Refract Surg, 33, pp.848~858 (2007)
- Shimozono M, "Corneal spherical aberration of eyes with cataract in a Japanese population", J Refract Surg, 26, pp.457~459 (2010)
- Chantra S, "Wavefront and ocular spherical aberration after implantation of different types of aspheric intraocular lenses based on corneal spherical aberration", J Med Assoc Thai, 94(Suppl 2), pp.71~75 (2011)
- Packer M, "Aspheric intraocular lens selection based on corneal wavefront", J Refract Surg, 25, pp.12~20 (2009)
- Wang L, "Age-related changes in corneal and ocular higher-order aberrations", Am J Ophthalmol, 138, pp.897~ (2004)
- Athaide HV, "Study of ocular aberrations with age", Arq Bras Oftalmol, 72, pp.617~621 (2009)
- 임태형, "Pentacam으로 측정한 정상 한국인에서 각막 전후면의 구면수차", 대한안과학회지, 51(6), pp.816~821 (2010), 대한안과학회