577 nm 레이저 섬유주성형술의 단기 임상효과
Short-Term Clinical Outcomes of Laser Trabeculoplasty Using a 577-nm Wavelength Laser
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목적: 577 nm 레이저를 이용한 단일 광응고반 레이저섬유주성형술과 패턴 레이저섬유주성형술의 안압 하강효과를 알아보고자 하였다. 대상과 방법: 원발개방각녹내장 환자 35명을 대상으로 18안은 360°단일 광응고반 레이저섬유주성형술을 시행하였고, 17안은 360°패턴레이저섬유주성형술을 시행하여 시술 후 1주, 1개월, 3개월, 6개월의 안압검사 및 세극등 현미경검사를 시행하였다. 결과: 단일 광응고반 레이저섬유주성형술을 시행한 군에서 술전 안압은 평균 25.27 ± 7.51 mmHg였고, 술후 6개월째 안압은 평균15.89 ± 3.89 mmHg로 술전에 비해 평균 37.1% 안압하강 효과가 있었다. 패턴 레이저 섬유주성형술을 시행한 군에서 술전 안압은평균 24.11 ± 4.17 mmHg였고, 술후 6개월째 안압은 평균 17.57 ± 2.64 mmHg로 술전에 비해 평균 27.1% 안압하강 효과가 있었다. 결론: Optically pumped semiconductor laser (577 nm)를 이용한 단일 광응고반 레이저섬유주성형술과 패턴 레이저섬유주성형술은안압하강 효과가 있으며, 시술방법에 따른 안압하강의 효과는 두 군간에 통계학적으로 유의한 차이는 없었다(p=0.40).
Abstract
Purpose: To evaluate the pressure-lowering effects of single-spot laser trabeculoplasty and patterned laser trabeculoplasty usinga 577-nm wavelength laser. Methods: A total 35 eyes of 35 patients with primary open-angle glaucoma were enrolled in this study. Eighteen eyes of 18 patientswere treated with 360° single-spot laser trabeculoplasty and 17 eyes of 17 patients were treated with 360° patterned lasertrabeculoplasty. All patients were evaluated after laser trabeculoplasty at 1 week, 1 month, 3 months, and 6 months using slitlamp examination and Goldmann applanation tonometry. Results: At 6 months postoperatively, the single-spot laser trabeculoplasty group had a mean IOP of 15.89 ± 3.89 mm Hg with amean IOP reduction of 37.1%, while the patterned laser trabeculoplasty group had a mean IOP of 17.57 ± 2.64 mm Hg with amean IOP reduction of 27.1%. Conclusions: Laser trabeculoplasty with a 577-nm optically pumped semiconductor laser was safe and demonstrated an IOPlowering effect. There were no significant differences in the IOP lowering effects between the single-spot laser trabeculoplastyand the patterned laser trabeculoplasty.
참고문헌 (19)
- Wise JB, "Argon laser therapy for open-angle glaucoma. A pilot study", Arch Ophthalmol, 97, pp.319~322 (1979)
- Latina MA, "Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions", Exp Eye Res, 60, pp.359~371 (1995)
- 조범주, "당뇨망막병증에서 짧은 노출시간을 이용한 패턴 범망막광응고술의 단기 임상결과", 대한안과학회지, 50(3), pp.376~382 (2009), 대한안과학회
- Turati M, "Patterned laser trabeculoplasty", Ophthalmic Surg Lasers Imaging, 41, pp.538~545 (2010)
- Hodapp E, "Clinical decisions in glaucoma", pp.52~61 (1993), Mosby
- Wise JB, "Glaucoma treatment by trabecular tightening with the argon laser", Int Ophthalmol Clin, 21, pp.69~78 (1981)
- Van Buskirk EM, "Argon laser trabeculoplasty. Studies of mechanism of action", Ophthalmology, 91, pp.1005~1010 (1984)
- Alvarado JA, "A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm’s canal endothelial cells", Br J Ophthalmol, 89, pp.1500~1505 (2005)
- Bradley JM, "Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1beta and TNFalpha", Invest Ophthalmol Vis Sci, 41, pp.422~430 (2000)
- Samples JR, "Laser trabeculoplasty for open-angle glaucoma: a report by the american academy of ophthalmology", Ophthalmology, 118, pp.2296~2302 (2011)
- Worthen DM, "Laser trabeculotomy in monkeys", Invest Ophthalmol, 12, pp.707~711 (1973)
- 박준정, "개방각녹내장 환자에서 아르곤레이저 섬유주성형술과 선택적 레이저 섬유주성형술의 임상효과 비교", 대한안과학회지, 49(9), pp.1491~1500 (2008), 대한안과학회
- Brancato R, "Diode laser compared with argon laser for trabeculoplasty", Am J Ophthalmol, 112, pp.50~55 (1991)
- Chung PY, "Five-year results of a randomized, prospective, clinical trial of diode vs argon laser trabeculoplasty for open-angle glaucoma", Am J Ophthalmol, 126, pp.185~190 (1998)
- Kramer TR, "Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes", Ophthalmology, 108, pp.773~779 (2001)
- Allingham RR, "Shields textbook of glaucoma", pp.455~ (2011), Lippincott Williams&Wlikins
- 장윤수, "180도와 360도 선택적 레이저섬유주성형술의 안압 하강효과 비교", 대한안과학회지, 53(2), pp.291~296 (2012), 대한안과학회
- Schuele G, "RPE damage thresholds and mechanisms for laser exposure in the microsecond-to-milisecond time regimen", Invest Ophthalmol Vis Sci, 46, pp.714~719 (2005)
- Sramek CK, "Therapeutic window of retinal photocoagulation with green (532-nm) and yellow (577-nm) lasers", Ophthalmic Surg Lasers Imaging, 43, pp.341~347 (2012)