Dynamic Contour Tonometry와 안혈류분석계의 안구 박동 크기 비교
Comparison of Ocular Pulse Amplitude Measured Using Dynamic Contour Tonometry and Ocular Blood Flow Analyzer
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목적: Dynamic contour tonometry (DCT)와 안구 혈류 분석계(blood flow analyser, BFA)를 이용해 측정한 안구 박동 크기를 비교하고자 한다. 대상과 방법: 본 연구는 후향적 단면 연구로 정상안 35명 35안을 대상으로 하였다. 안구 박동 크기(ocular pulse amplitude, OPA)는DCT를 이용하여 측정하였고 박동 크기(pulse amplitude, PA) 및 박동 안구 혈류(pulsatile ocular blood flow, POBF)는 BFA를 통해 측정하였다. 결과: DCT를 이용해 측정한 OPA (2.79 ± 0.89 mmHg)는 BFA를 이용해 측정한 PA (3.02 ± 0.90 mmHg)와 유의한 차이는 없었고(p=0.082) 두 측정치 간에는 유의한 상관관계를 보였다(r=0.663, p＜0.001). OPA와 PA 사이의 Mean difference ± limit of agreement는 -0.22 ± 1.44 mmHg였다. OPA는 골드만 안압계로 측정된 안압과 유의한 상관관계를 보였으나(r=0.330, p=0.047) PA 는 그렇지 않았다(r=0.057, p=0.745). PA와 OPA는 모두 굴절이상의 구면렌즈 대응치와 중심각막두께와는 유의한 상관관계를 보이지 않았다. 결론: OPA와 PA는 모두 안압 측정 시 안압의 변동폭을 나타내는 값이며 유의한 차이는 없었으나 각각의 값과 안압과의 상관관계는 서로 다른 경향을 보였다.
Abstract
Purpose: To compare ocular pulse amplitude (OPA) measured using dynamic contour tonometry (DCT) and ocular blood flow analyzer (BFA). Methods: Thirty-five eyes of 35 patients were enrolled in this cross-sectional and retrospective study. OPA was measured using DCT. Pulse amplitude (PA) and pulsatile ocular blood flow were measured using BFA. Results: OPA measured using DCT (2.79 ± 0.89 mm Hg) was not significantly different from PA measured with BFA (3.02 ± 0.90 mm Hg; p = 0.082) and both were significantly correlated (r = 0.663, p < 0.001). Mean difference ± limit of agreement was -0.22 ± 1.44 mm Hg between OPA and PA. OPA correlated significantly with intraocular pressure (IOP) measured using Goldmann applanation tonometry (r = 0.330, p = 0.047) but not PA (r = 0.057, p = 0.745). Both PA and OPA did not show significant correlation with the spherical equivalent of refractive error and central corneal thickness. Conclusions: Although both OPA and PA measure IOP fluctuation and are not significantly different, they showed different relationships with IOP.
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