재발 군날개 치료에 있어서 하측 구결막피판회전술의 치료 효과
The Effect of Inferior Conjunctival Transposition Flap for Recurrent Pterygium
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
목적: 본 연구에서는 재발 군날개 치료에 있어서 하측 구결막피판회전술의 치료 효과를 알아보고자 하였다. 대상과 방법: 재발 군날개로 진단되어 하측 구결막피판회전술을 시행 받은 60명 63안을 대상으로 하였다. 재발된 섬유혈관조직을 절제한 뒤 하측 구결막에서 회전 피판을 만들어 섬유혈관조직이 제거되어 노출된 공막에 흡수성 봉합사(8-0 VICRYLⓇ)로 봉합하여 고정하였다. 수술 후 6개월 이상 경과관찰 가능했던 환자들을 대상으로 재발률 및 합병증을 후향적으로 조사하였다. 결과: 평균 경과관찰 기간은 5년 8개월(6개월-14년)로 63안 중 4안(6.3%)에서 각막 재발을 보였으며 2안(3.1%)에서 결막 재발이 있었다. 결막 재발을 보인 2안 중 1안은 윤부까지, 다른 1안은 피판 봉합부위에 국한되어 있었고 더 진행하지는 않았다. 각막 재발을 보인 1안에서 추가적인 결막붙음분리술과 자가결막이식술이 필요했다. 이 외 수술 후 초기에 피판의 울혈, 출혈 및 결막 육아종이 관찰되었으나 경과관찰 중에 호전되었다. 결론: 재발 군날개 치료법에 있어서 하측 구결막피판회전술은 효과적이고 안전한 수술법이라 생각된다.
Abstract
Purpose: In the present study, the effect of the inferior conjunctival transposition flap in patients with recurrent pterygium was evaluated. Methods: This study included 60 patients (63 eyes) that received pterygium surgery with inferior conjunctival transposition flap and diagnosed with recurrent pterygium. The inferior conjunctival transposition flap obtained from lower bulbar conjunctiva was secured with 8-0 VICRYL® after removal of recurrent fibrovascular tissues. This study was retrospectively reviewed for recurrence and postoperative complications in patients with a minimum follow-up period over 6 months. Results: The mean follow-up period was 5 years and 8 months (range; 6 months to 14 years). Corneal recurrence occurred in 4 eyes (6.3%) and conjunctival recurrence was observed in 2 eyes (3.1%) among a total of 63 eyes. Conjunctival recurrence was not the progressive type and limited to the limbus and suture site. One case of corneal recurrence required additional symblepharolysis and auto conjunctival graft. Although mild flap congestion, hemorrhage and granuloma were observed, these cases improved during the follow-up period. Conclusions: The inferior conjunctival transposition flap procedure can be regarded as an effective surgical treatment option for recurrent pterygium.
참고문헌 (44)
- Rosenthal JW, "Chronology of pterygium therapy", Am J Ophthalmol, 36, pp.1601~1616 (1953)
- Coroneo MT, "Pterygium as an early indicator of ultraviolet insolation : a hypothesis", Br J Ophthalmol, 77, pp.734~739 (1993)
- Saw SM., "Pterygium : prevalence, demography and risk factors", Ophthalmic Epidemiol, 6, pp.219~228 (1999)
- Morgan DJ., "Pterygium and ultraviolet radiation : a positive correlation", Br J Opthalmol, 68, pp.343~346 (1984)
- Coroneo MT., "The pathogenesis of pterygia", Curr Opin Ophthalmol, 10, pp.282~288 (1999)
- Mckeown CM., "An autosomal dominant multiple pterygium syndrome", J Med Genet, 25, pp.96~103 (1988)
- Mackenzie FD., "Risk analysis in the development of pterygia", Ophthalmology, 99, pp.1056~1061 (1992)
- Tananuvat N., "The results of amniotic membrane transplantation for primary pterygium compared with conjunctival autograft", Cornea, 23, pp.458~463 (2004)
- Ehrlich D, "The management of pterygium", Ophthalmic Surg, 8, pp.23~30 (1977)
- Hirst LW., "Pterygium recurrence time", Ophthalmology, 101, pp.755~758 (1994)
- Shehadeh-Mashor R., "Management of recurrent pterygium with intraoperative mitomycin C and conjunctival autograft with fibrin glue", Am J Ophthalmol, 152, pp.730~732 (2011)
- Taylan Sekeroglu H., "Sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft for pterygium", Int Ophthalmol, 31, pp.433~438 (2011)
- Mutlu FM., "A comparative study of recurrent pterygium surgery : limbal conjuctival autograft transplantation versus mitomycin C with conjunctival flap", Ophthalmology, 106, pp.817~821 (1999)
- Kim S., "Primary pterygium surgery using the inferior conjunctival transposition flap", Ophthalmic Surg Lasers, 29, pp.608~611 (1998)
- Prabhasawat P., "Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision", Ophthalmology, 104, pp.974~985 (1997)
- Bahrassa F., "Postoperative beta radiation treatment of pterygium", Int J Radiat Oncol Biol Phys, 9, pp.679~684 (1983)
- Mauro J., "Pterygia : pathogenesis and the role of subconjunctival bevacizumab in treatment", Semin Ophthalmol, 24, pp.130~134 (2009)
- Chen CW., "Trabeculectomy with simultaneous topical application of mitomycin-C in refractory glaucoma", J Ocul Phamacol, 6, pp.175~182 (1990)
- Frucht-Pery J., "The use of low-dose mitomycin C for prevention of recurrent pterygium", Ophthalmology, 101, pp.759~762 (1994)
- Carrasco MA., "Scleral ulceration after preoperative injection of mitomycin C in the pterygium head", Arch Ophthalmol, 120, pp.1585~1586 (2002)
- Peponis V., "Fungal scleral keratitis and endophthalmitis following pterygium excision", Eur J ophthalmol, 19, pp.478~480 (2009)
- Rubinfeld RS., "Serious complications of topical mitomycin-C after pterygium surgery", Ophthalmology, 99, pp.1647~1654 (1992)
- Lindquist TP., "Mitomycin C-associated scleral stromalysis after pterygium surgery", Cornea, 34, pp.398~401 (2015)
- Lam DS., "Intraoperative Mitomycin C to Prevent Recurrence of Pterygium after Excision: A 30 Months Follow-up Study", Ophthalmology, 105, pp.901~904 (1998)
- Tarr KH., "Late complications of pterygium treatment", Br J Ophthalmol, 64, pp.496~505 (1980)
- Kria L., "Immunohistochemical localization of basic fibroblast growth factor, platelet derived growth factor, transforming growth factor-beta and tumor necrosis factor-alpha in pterygium", Acta Histochem, 98, pp.195~201 (1996)
- Aspiotis M., "Angiogenesis in pterygium : study of microvessel density, vascular endothelial growth factor, and thrombospondin-1", Eye(Lond), 21, pp.1095~1101 (2007)
- Fallah MR., "Efficacy of topical bevacizumab for inhibiting growth of impending recurrent pterygium", Curr Eye Res, 35, pp.17~22 (2010)
- Lekhanont K., "Randomized controlled trial of subconjunctival bevacizumab injection in impending recurrent pterygium : a pilot study", Cornea, 31, pp.155~161 (2012)
- Erdumus M., "Subconjunctival bevacizumab for corneal neovascularization", Graefes Arch Clin Exp Ophthalmol, 245, pp.1577~1579 (2007)
- Mansour AM, "Treatment of inflamed pterygia or residual pterygial bed", Br J Ophthalmol, 93, pp.864~865 (2009)
- Razeghinejad MR., "Preliminary results of subconjunctival bevacizumab in primary pterygium excision", Ophthalmic Res, 43, pp.134~138 (2010)
- Kenyon KR., "Conjunctival autograft transplantation for advanced and recurrent pterygium", Ophthalmology, 92, pp.1461~1470 (1985)
- Hirst LW, "Recurrent pterygium surgery using pterygium extended removal followed by extended conjunctival transplant : recurrence rate and cosmesis", Ophthalmology, 116, pp.1278~1286 (2009)
- Mery G., "Limbal-conjunctival autograft in pterygium surgery", J Fr Ophthalmol, 33, pp.92~98 (2010)
- McCoombes JA., "Sliding conjunctival flap for the treatment of primary pterygium", Ophthalmology, 101, pp.169~173 (1994)
- Lei G, "Surgery for pterygium using a conjunctival pedunculated flap slide", Br J Ophthalmol, 80, pp.33~34 (1996)
- 조정우, "익상편수술시 결막소판술과 자가결막이식술의 재발률 비교", 대한안과학회지, 46(9), pp.1471~1477 (2005), 대한안과학회
- 홍성민, "원발 군날개 수술에서 하측 구결막피판회전술의 치료효과", 대한안과학회지, 50(12), pp.1774~1779 (2009), 대한안과학회
- Adamis AP., "The management of pterygium", Ophthalmol Clin North Am, 3, pp.611~623 (1990)
- Pan HW., "Comparison of fibrin glue versus suture for conjunctival autografting in pterygium surgery : a meta-analysis", Ophthalmology, 118, pp.1049~1054 (2011)
- Mandour SS., "Preoperative subpterygial mitomycin C injection versus limbal conjunctival autograft transplantation for prevention of pterygium recurrence", J Ocul Phamacol Ther, 27, pp.481~485 (2011)
- José Bonifácio Barbosa, "Amniotic membrane transplantation with narrow-strip conjunctival autograft vs conjunctival autograft for recurrent pterygia", European Journal of Ophthalmology, pp.0~0 (2016), Wichtig Publishing, SRL[DOI]
- Al Fayez MF, "Limbal versus conjunctival autograft transplantation for advanced and recurrent pterygium", Ophthalmology, 109, pp.1752~1755 (2002)
