나이와 크기에 따른 콩다래끼 병소 내 스테로이드 국소주사의 치료 효과 비교
Comparison of Intralesional Triamcinolone Acetonide Injection Efficacy for Chalazion According to Age and Lesion Size
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
목적: 나이와 크기에 따른 콩다래끼 병소 내에 시행한 스테로이드 국소주사의 효과에 대하여 비교연구해보고자 하였다. 대상과 방법: 2017년 1월부터 2018년 2월까지 본원에서 콩다래끼로 진단 받고 스테로이드 국소 주입술을 시행 받은 108명의 환자를 대상으로 하였다. 환자를 나이 및 병소의 크기에 따라 세 군으로 나누어 다래끼 크기에 따라 사용한 약제의 치료 성공률, 합병증 등을 후향적으로 조사하였다. 결과: 전체 108병소의 콩다래끼 치료 누적 성공률은 1회 주사로 69.4%, 2회 주사로 80.6%였으며, 2회 주사까지 고려한 7세 미만의 환자 30병소, 7세 이상 17세 미만의 22병소, 17세 이상의 56병소에서 각각 누적 성공률은 86.7%, 81.8%, 76.8%였다. 콩다래끼 병소의 지름 10 mm 미만 27병소, 10 mm 이상 15 mm 미만 70병소, 15 mm 이상 20 mm 미만 11병소에서 누적 성공률을 보면 85.2%, 80%, 72.7%로 각각 확인되었으나, 통계적으로 유의한 차이는 보이지 않았다. 결론: 콩다래끼의 치료에 있어서 스테로이드 국소주사는 매우 유용하며 특히 나이가 어릴수록, 크기가 작을수록 치료 효과가 좋다.
Abstract
Purpose: The purpose of this study was to compare the efficacy of intralesional triamcinolone acetonide injection in the treatment of chalazion according to age and size of the lesion. Methods: We performed a retrospective chart review of 108 patients (108 lesions) who underwent intralesional triamcinolone acetonide injections between January 2017 and February 2018. Patients were divided into three groups according to their age and size of the lesion and evaluated with respect to the treatment success and complications. Results: Cumulative treatment success of intralesional triamcinolone acetonide injection was 69.4% with the first injection and 80.6% with the second injection in 108 lesions. With respect to age, 30 lesions were observed in patients under the age of 7 years, 22 lesions were found in patients aged 7 to 16 years, and 56 lesions were observed in patients who were 17 years or older; cumulative treatment success percentages with second injections were 86.7%, 81.8%, and 76.8% respectively. Twenty-seven lesions were under 10 mm in size, 70 lesions ranged from 10 to 15 mm, and 11 lesions were sized 16 to 20 mm; cumulative treatment success percentages were 85.2%, 80%, and 72.7% respectively. Although the results were not statistically significant. Conclusions: Intralesional triamcinolone acetonide injection in chalazion is more effective for smaller lesions and younger pediatric patients.
참고문헌 (17)
- Dubey R, "Management of marginal chalazia : a surgical approach", Br J Ophthalmol, 95, pp.590~ (2011)
- Pizzarello LD, "Intralesional corticosteroid therapy of chalazia", Am J Ophthalmol, 85, pp.818~821 (1978)
- Ben Simon GJ, "Intralesional triamcinolone acetonide injection for primary and recurrent chalazia : is it really effective", Ophthalmology, 112, pp.913~917 (2005)
- Watson AP, "Treatment of chalazions with injection of asteroid suspension", Br J Ophthalmol, 68, pp.833~835 (1984)
- Friedman SJ, "Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy : report of two cases and review of the literature", J Am Acad Dermatol, 19, pp.537~541 (1988)
- Hoşal BM, "Ocular complication of intralesional corticosteroid injection of a chalazion", Eur J Ophthalmol, 13, pp.798~799 (2003)
- Dhaliwal U, "A rationale for therapeutic decision making in chalazia", Orbit, 24, pp.227~230 (2005)
- Mustafa TA, "Three methods of treatment of Chalazia in children", Saudi Med J, 22, pp.968~972 (2001)
- 박주홍, "소아 환자에서 콩다래끼 병소내에 시행한 스테로이드 국소주사의 유효성", 대한안과학회지, 50(9), pp.1295~1300 (2009), 대한안과학회
- Ben Simon GJ, "Intralesional triamcinolone acetonide injection versus incision and curettage for primary chalazia : a prospective, randomized study", Am J Ophthalmol, 151, pp.714~718 (2011)
- 이종욱, "원발성 콩다래끼 환자에서 병소 내 트리암시놀론주사요법과 절개배농술의 치료 효과 비교", 대한안과학회지, 54(10), pp.1488~1493 (2013), 대한안과학회
- Park JH, "Eyelid fat atrophy and depigmentation after an intralesional injection of triamcinolone acetonide to treat chalazion", J Craniofac Surg, 28, pp.e198~e199 (2017)
- Yağci A, "Anterior segment ischemia and retinochoroidal vascular occlusion after intralesional steroid injection", Ophthal Plast Reconstr Surg, 24, pp.55~57 (2008)
- Shorr N, "Central retinal artery occlusion associated with periocular corticosteroid injection for juvenile hemangioma", Ophthalmic Surg, 17, pp.229~231 (1986)
- Moshfeghi DM, "Retinal and choroidal vascular occlusion after posterior sub-tenon triamcinolone injection", Am J Ophthalmol, 134, pp.132~134 (2002)
- Wilkinson WS, "Retinal and choroidal vascular occlusion secondary to corticosteroid embolisation", Br J Ophthalmol, 73, pp.32~34 (1989)
- Wong YY, "Intralesional triamcinolone acetonide injection for the treatment of primary chalazions", Int Ophthalmol, 34, pp.1049~1053 (2014)