나이관련황변변성 환자들의 항산화 영양제 복용에 대한 설문조사
Survey of AREDS2 Formula Intake in Korean Patients with Age-related Macular Degeneration
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목적: 중등도 이상의 황반변성을 진단받고 AREDS2 formula를 복용하고 있는 환자들의 복용 실태에 대해서 조사해 보고자 하였다. 대상과 방법: 2019년 12월부터 2020년 7월까지 황반변성 환자를 대상으로 전향적으로 설문조사를 시행하였다. 설문지는 인구학적 특성, 질병에 대한 인식, 영양제 복용 실태 등에 대해 총 24문항을 조사하였다. 결과: 총 100명의 환자가 포함되었으며, 남자가 56%였고 연령은 60대 이상이 89%였다. 질환에 대한 이해도, 금연의 필요성, 항산화 영양제의 필요성에 대해 안다고 대답한 비율은 66%, 84%, 93%였다. 복용 실태 조사에서 복용 중인 약을 정확히 알고 있는 환자는 58%였고, 이 중 AREDS2 영양제를 제대로 복용하고 있는 환자는 63.8% (전체 환자의 37%)였다. 또한, 영양제 성분에 대해서 알고 있는 환자는 8%, 영양제를 매일 복용한다고 답한 환자는 91%였다. 복용 실태와 인식에 영향을 미치는 인자로 유병 기간이 길어질수록 황반변성 영양제를 복용하는 빈도가 줄어드는 경향이 있었으며(p＜0.05), 연령이 높고 저학력일수록 황반변성질환에 대한 인지가 낮았다(p＜0.05). 결론: 황반변성 영양제 복용 실태 조사에서 정확한 AREDS2 formula를 복용하지 않는 환자들이 있어 이에 대한 보완책이 필요할 것으로 생각된다.
Abstract
Purpose: To investigate the use of second AREDS2 formula in patients with intermediate or advanced age-related macular degeneration. Methods: A prospective survey was conducted between December 2019 and July 2020. The questionnaire consisted of 24 questions on demographics, disease perception, and formula intake. Results: The survey included 100 patients (males, 56%; age [>60 years], 89%). We found that 66%, 84%, and 93% of patients had a good understanding of their disease, had stopped smoking, and were aware of the need for antioxidant supplements; 58% of patients were aware of the supplement they were prescribed, and 63.8% (37% of total) were using the AREDS2 formula. Only 8% of patients had knowledge regarding the supplement ingredients, and 91% consumed the supplement daily. Patients with long disease duration used supplements less frequently (p < 0.05). Older patients and those with a low education level had a limited perception of the disease (p < 0.05). Conclusions: In this prospective survey, some patients consumed supplements other than the AREDS2 formula. Further studies are required to determine ways to increase the use of the AREDS2 formula.
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