본문 바로가기
KERD
논문KCI 등재

Food Sensitization in Infants and Young Children with Atopic Dermatitis

이수영|유재은|권병철|최성연|김명관|손명현|김규언|한동기
연세대학교의과대학 (Yonsei University College of Medicine)|2004.10|Yonsei Medical Journal|제45권 제5호|pp. 803-809

2

조회

0

다운로드

7

인용

0

참고문헌

주제분류의학일반

초록

Abstract

Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease. Children with AD tend to have a higher prevalence of food allergies. This study investigated the clinical significance of food sensitization in AD patients. A total of 266 AD patients participated in this study. The prevalence of food sensitization and clinically relevant sensitization were compared in the subjects according to their age and AD severity. Sera from all patients were analyzed for food-specific IgE levels using the Pharmacia CAP System FEIA. The serum specific IgE levels for egg, milk, peanut and soybean were measured. Patients were regarded as sensitized to the food if their food-specific IgE levels were above 0.35kUA/L. Also the food-specific IgE levels, the so-called diagnostic decision point, which is recommended as the clinically relevant level, for clinical food allergy, as suggested by Sampson et al, was used as an alternative method. From the measurement of food-specific IgE antibodies of the four foods, egg was the most highly sensitized and the main causative allergenic food in children with AD. The positive rates of specific IgE to the four major food allergens, and the prevalences of clinically relevant food sensitization, were higher for all foods tested in the group less than 1 year of age, and were significantly higher in moderate to severe AD compared to mild AD in infants and young children. In summary, presence of food specific IgE is prevalent in infants and young children with AD, and clinically relevant food sensitization is important in Korean infants and children with moderate to severe AD.

참고문헌 (25)

  1. "Epidemiology of atopic dermatitis", 22, pp.1~24 (2002)
  2. "Nationwide study for epidemiological change of atopic dermatitis in school aged children between 1995 and 2000 and kindergarten aged children in 2003 in Korea", 13, pp.227~237 (2003)
  3. "Prevalence of IgE-mediated food allergy among children with atopic dermatitis", 101, pp.E8~ (1998)
  4. "Food allergy. Part 1: immunopathogenesis and clinical disorders", 103, pp.717~728 (1999)
  5. "Outcome of double-blind, placebo-controlled food challenge tests in 107 children with atopic dermatitis", 29, pp.91~96 (1999)
  6. "Atopic dermatitis and food hypersensitivity reactions", 132, pp.132~136 (1998)
  7. "Atopic dermatitis: the skin as a window into the pathogenesis of chronic allergic diseases", 96, pp.302~318 (1995)
  8. "Epidemiology of atopic dermatitis", 21, pp.116~131 (1987)
  9. "Prospect of appraisal of complaints of adverse reactions to foods in children during the first 3years of life", 79, pp.683~688 (1987)
  10. "Serum IgE concentration in atopic dermatitis. Relationship to severity of disease and presence of atopic respiratory disease", 54, pp.94~99 (1974)
  11. "Studies in absorption of undigested proteins in human beings: I. A simple direct method of studying the absorption of undigested protein", 14, pp.143~174 (1927)
  12. "Absorption of undigested proteins in human beings, IV: absorption of unaltered egg protein in infants", 50, pp.49~54 (1935)
  13. "Role of immediate food hypersensitivity in the pathogenesis of atopic dermatitis", 71, pp.473~480 (1983)
  14. "Food Allergy. Part 2: Diagnosis and management", 103, pp.981~999 (1999)
  15. "Diagnostic features of atopic dermatitis", 92, pp.44~47 (1980)
  16. "Quantitative IgE antibody assays in allergic diseases", 105, pp.1077~1084 (2000)
  17. "Relationship between food- specific IgE concentrations and the risk of positive food challenges in children and adolescents", 100, pp.444~451 (1997)
  18. "Utility of food-specific IgE concentrations in predicting symptomatic food allergy", 107, pp.891~896 (2001)
  19. "Food hypersensitivity and atopic dermatitis: evaluation of 113 patients", 107, pp.669~675 (1985)
  20. "An update on food hypersensitivity", 2, pp.121~133 (1994)
  21. "Atopic dermatitis: clinical relevance of food hypersensitivity reactions", 113, pp.447~451 (1988)
  22. "A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema", 1, pp.401~403 (1978)
  23. "Natural history of sensitizations in atopic dermatitis. A 3-year follow-up in 250 children: food allergy and high risk of respiratory symptoms", 128, pp.187~192 (1992)
  24. "Atopic dermatitis and food allergy", 8, pp.271~276 (1998)
  25. "The incidence and principle foods of food allergy in children with asthma", 5, pp.96~106 (1995)

관련 논문AI추천

영유아 아토피피부염의 위험 인자편복양대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2005 · 제15권 제3호Triggers of Atopic DermatitisBurks KD대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2004 · 제14권 제4호아토피피부염 영아에서 유아식 유형에 따른 임상증상, 영양상태 및 면역 지표의 변화류경아, 오재원, 이은영, 이하백, 임정은, 조여원대한천식알레르기학회 · 천식 및 알레르기2007 · 제27권 제1호영아 아토피피부염에서 알레르기 감작과 IgE 매개 여부에따른 임상 양상김가람, 나민선, 신윤호, 이경석, 이승진, 정영호, 지혜미, 최선희, 하은교, 한만용대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2017 · 제5권 제3호Hair Mineral Analysis in Children with Atopic Dermatitis고주연, 김정은, 노영석, 신재민대한피부과학회 · Annals of Dermatology2017 · 제29권 제2호Association of Atopic Dermatitis with Dyslipidemia in Adolescents: A Cross-Sectional Study민유선, 박희재, 이자호, 전성민, 최미라대한피부과학회 · Annals of Dermatology2021 · 제33권 제5호

이 간행물의 다른 논문 (7건)

Antioxidant Effects of Sulfur-containing Amino AcidsGulizar Atmacapp. 776-788Mutations of the BRAF Gene in Papillary Thyroid Carcinoma in a Korean Population김성호, 성인옥, 김경희, 강대영, 강동욱pp. 818-821The Effects of Urokinase Instillation Therapy via Percutaneous Transthoracic Catheter in Loculated Tuberculous Pleural Effusion: A Randomized Prospective Study장준, 박찬섭, 김세규, 김성규, 조재화, 곽승민, 류정선pp. 822-828Association between Job Stress on Heart Rate Variability and Metabolic Syndrome in Shipyard Male Workers고상백, 장세진, 강명근, 차봉석, 박종구, 우종민pp. 838-846Comparison of Femoral Geometry among Cases with and without Hip FracturesMustafa Calis, Merih Eryavuz, Havva Talay Calispp. 901-907
원문 보기