Oxidative stress status and reproductive performance of sows during gestation and lactation under different thermal environments
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Objective: Two experiments were conducted using 28 healthy multiparous sows to evaluate the oxidative stress status and reproductive performance of sows during gestation and lactation under different thermal environments. Methods: Fourteen multiparous sows were used in Exp. 1 under a high thermal environment, and the other 14 multiparous sows were used in Exp. 2 under a moderate thermal environment. In both experiments, reproductive performances of sows were recorded. Plasma samples were collected on d 35, 60, 90, and 109 of gestation, and d 1 and 18 of lactation for malondialdehyde, protein carbonyls, 8-hydroxy-deoxyguanosine, immunoglobulin g (IgG), and IgM analysis. Results: For sows in Exp. 1, plasma malondialdehyde concentration on d 109 of gestation tended to be greater (p<0.05) than it on d 18 of lactation. Plasma concentration of protein carbonyl on d 109 of gestation was the greatest (p<0.05) compared with all the other days. Plasma concentrations of 8-hydroxy-deoxyguanosine on d 109 of gestation was greater (p< 0.05) than d 18 of lactation in Exp. 1. For sows in Exp. 2, there was no difference of malondialdehyde and protein carbonyl concentration during gestation and lactation. In both Exp. 1 and 2, litter size and litter weight were found to be negatively correlated with oxidative stress indicators. Conclusion: Sows under a high thermal environment had increased oxidative stress during late gestation indicating that increased oxidative damage to lipid, protein, and DNA could be one of the contributing factors for reduced reproductive performance of sows in this environment. This study indicates the importance of providing a moderate thermal environment to gestating and lactating sows to minimize the increase of oxidative stress during late gestation which can impair reproductive outcomes.
Abstract
Objective: Two experiments were conducted using 28 healthy multiparous sows to evaluate the oxidative stress status and reproductive performance of sows during gestation and lactation under different thermal environments. Methods: Fourteen multiparous sows were used in Exp. 1 under a high thermal environment, and the other 14 multiparous sows were used in Exp. 2 under a moderate thermal environment. In both experiments, reproductive performances of sows were recorded. Plasma samples were collected on d 35, 60, 90, and 109 of gestation, and d 1 and 18 of lactation for malondialdehyde, protein carbonyls, 8-hydroxy-deoxyguanosine, immunoglobulin g (IgG), and IgM analysis. Results: For sows in Exp. 1, plasma malondialdehyde concentration on d 109 of gestation tended to be greater (p<0.05) than it on d 18 of lactation. Plasma concentration of protein carbonyl on d 109 of gestation was the greatest (p<0.05) compared with all the other days. Plasma concentrations of 8-hydroxy-deoxyguanosine on d 109 of gestation was greater (p< 0.05) than d 18 of lactation in Exp. 1. For sows in Exp. 2, there was no difference of malondialdehyde and protein carbonyl concentration during gestation and lactation. In both Exp. 1 and 2, litter size and litter weight were found to be negatively correlated with oxidative stress indicators. Conclusion: Sows under a high thermal environment had increased oxidative stress during late gestation indicating that increased oxidative damage to lipid, protein, and DNA could be one of the contributing factors for reduced reproductive performance of sows in this environment. This study indicates the importance of providing a moderate thermal environment to gestating and lactating sows to minimize the increase of oxidative stress during late gestation which can impair reproductive outcomes.
참고문헌 (30)
- Betteridge DJ, "What is oxidative stress?", Metabolism, 49, pp.3~8 (2000)[DOI]
- Gutteridge JM, "Lipid peroxidation and antioxidants as biomarkers of tissue damage", Clin Chem, 41, pp.1819~1828 (1995)[DOI]
- Hall ED, "Efficacy and mechanisms of action of the cytoprotective lipid peroxidation inhibitor tirilazad mesylate in subarachnoid haemorrhage", Eur J Anaesthesiol, 13, pp.279~289 (1996)[DOI]
- Bottje WG, "Antioxidant defenses in lung lining fluid of broilers : impact of poor ventilation conditions", Poult Sci, 77, pp.516~522 (1998)[DOI]
- Zhao Y, "Effect of social ranks and gestation housing systems on oxidative stress status, reproductive performance, and immune status of sows", J Anim Sci, 91, pp.5848~5858 (2014)[DOI]
- Renaudeau D, "Effects of exposure to high ambient temperature and dietary protein level on sow milk production and performance of piglets", J Anim Sci, 79, pp.1540~1548 (2001)[DOI]
- Black JL, "Lactation in the sow during heat stress", Livest Prod Sci, 35, pp.153~170 (1993)[DOI]
- Renaudeau D, "Effects of exposure to high ambient temperature and dietary protein level on performance of multiparous lactating sows", J Anim Sci, 79, pp.1240~1249 (2001)[DOI]
- Flowers B, "Alterations in gonadotropin secretion and ovarian function in prepubertal gilts by elevated environmental temperature", Biol Reprod, 42, pp.465~471 (1990)[DOI]
- Zhang H, "Effect of dietary fat supplementation on milk components and blood parameters of early-lactating cows under heat stress", Slovak J Anim Sci, 44, pp.52~58 (2011)
- Wegner K, "Climatic effects on sow fertility and piglet survival under influence of a moderate climate", Animal, 8, pp.1526~1533 (2014)[DOI]
- Ji F, "Weight and compositional changes in pregnant gilts and its implication to nutrition", J Anim Sci, 83, pp.366~375 (2005)
- Kim SW, "Regulatory role for amino acids in mammary gland growth and milk synthesis", Amino Acids, 37, pp.89~95 (2009)[DOI]
- Berchieri-Ronchi CB, "Oxidative stress status of highly prolific sows during gestation and lactation", Animal, 5, pp.1774~1779 (2011)[DOI]
- Committee on Nutrient Requirements of Swine, National Research Council, "Nutrient requirements of swine" (2012), National Academy Press
- Shen YB, "Effect of feed grade L-methionine on growth performance and gut health in nursery pigs compared with conventional DL-methionine", J Anim Sci, 92, pp.5530~5539 (2014)[DOI]
- Weaver AC, "Supplemental nucleotides high in inosine 5-monophosphate to improve the growth and health of nursery pigs", J Anim Sci, 92, pp.645~651 (2014)[DOI]
- Chaytor AC, "Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs", J Anim Sci, 89, pp.124~135 (2011)[DOI]
- Huynh TTT, "Effects of increasing temperatures on physiological changes in pigs at different relative humidities", J Anim Sci, 83, pp.1385~1396 (2005)[DOI]
- Botto L, "The effect of evaporative cooling on climatic parameters in a stable for sows", Res Agric Eng, 60, pp.S85~91 (2014)[DOI]
- Seedorf J, "Temperature and moisture conditions in livestock buildings in Northern Europe", J Agric Eng Res, 70, pp.49~57 (1998)[DOI]
- Britt JH, "Characterization of summer infertility of sows in large confinement units", Theriogenology, 20, pp.133~140 (1983)[DOI]
- Robertshaw D, "Environmental aspects of housing for animal production", pp.3~17 (1981), Butterworths
- Ozawa M, "Developmental competence and oxidative state of mouse zygotes heat-stressed maternally or in vitro", Reproduction, 124, pp.683~689 (2002)[DOI]
- Matsuzuka T, "Effects of heat stress on the redox status in the oviduct and early embryonic development in mice", J Reprod Dev, 51, pp.281~287 (2005)[DOI]
- Mujahid A, "Acute heat stress induces oxidative stress and decreases adaptation in young white leghorn cockerels by downregulation of avian uncoupling protein", Poult Sci, 86, pp.364~371 (2007)[DOI]
- Mujahid A, "Sequential changes in superoxide production, anion carriers and substrate oxidation in skeletal muscle mitochondria of heat-stressed chickens", FEBS Lett, 581, pp.3461~3467 (2007)[DOI]
- Karowicz-Bilinska A, "Evaluation of oxidative stress indices during treatment in pregnant women with intrauterine growth retardation", Med Sci Monit, 8, pp.CR211~CR216 (2002)
- Toy H, "Serum prolidase activity and oxidative stress markers in pregnancies with intrauterine growth restricted infants", J Obstet Gynaecol Res, 35, pp.1047~1053 (2009)[DOI]
- McGlone JJ, "Reviews : Compilation of the scientific literature comparing housing systems for gestating sows and gilts using measures of physiology, behavior, performance, and health", Prof Anim Sci, 20, pp.105~117 (2004)[DOI]