비만이 동반된 폐쇄성 수면무호흡증 환자에 있어서 수술 후에 시행한 체중감량이 환자의 삶의 질에 미치는 영향
The Effect of the Postoperative Weight Reduction on the Quality of the Life in the Patients with Obstructive Sleep Apnea Syndrome and Obesity
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Abstract
Background and Objectives：The incidence of obstructive sleep apnea syndrome (OSAS) among obese patients is about three times higher than that of non-obese patients. Obesity is the most significant risk factor of OSAS. But in the treatment of OSAS, we tended to neglect treating obesity till now. The aim of this study was to assess the effect of weight loss after surgery on the quality of the life in OSAS patients with obesity. Subjects and Method：Twenty OSAS patients with obesity (body mass index >25) completed the preoperative SF-36v2TM questionnaire. All patients were treated by LAUP or UPPP. Ten of them (experimental group) were induced to lose weight by 10 mg of sibutramine for 3 months whereas nothing was done in the others (control group). And then all patients completed the same questionnaire again. The changes of the SF-36v2TM scores have been assessed. Results：In the experimental group, the mean BMI decreased from 30.2 to 28.4 (p<0.05), the mean physical component sum-mary of SF-36v2TM scores was increased from 50.2 to 54.6 (p<0.05) and mean mental component summary was also increased from 45.8 to 49.6 (p<0.05). But in the control group, only mean mental component summary was statistically increased from 49.1 to 50.8. Conclusion：This study demonstrates that the trial of postoperative weight loss may improve the quality of life in OSAS patients with obesity. So we must consider the positive trial of weight loss as well as the surgeries in the treatment of OSAS patients with obesity
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