본문 바로가기
KERD
논문KCI 등재

재발성 호흡기 유두종증

Recurrent Respiratory Papillomatosis

이상준
대한이비인후과학회 (Korean Society of Otorhinolaryngology-Head and Neck Surgery)|2015.12|대한이비인후과학회지 두경부외과학 (Korean Journal of Otorhinolaryngology-Head and Neck Surgery)|제58권 제12호|pp. 822-830|DOI http://dx.doi.org/10.3342/kjorl-hns.2015.58.12.822

1

조회

0

다운로드

1

인용

0

참고문헌

키워드

LaserHuman papillomavirusRecurrent respiratory papillomatosisAdjuvant therapy
주제분류이비인후과학

초록

Recurrent respiratory papillomatosis (RRP) is benign neoplasm caused by human papillomavirus. Although RRP arises in anywhere along the airway, the most common site is larynx. RRP has bimodal onset during either childhood or adulthood. Childhood-onset RRP is presented with more aggressive disease, which is associated with higher recurrence rate and spread to distal airway. At present, there is no single modality to eradicate RRP. The current standard treatment is repeated surgical removal of papilloma and preservation of normal structures as far as possible. When repeated surgery is needed more than 4 times per year or disease involves the distal airway, nonsurgical adjuvant therapies should be considered. Several adjuvant therapies have been tried and some showed effectiveness for advanced RRP. Because of its severe impact on children’s heath, latest knowledge of RRP is essential to otolaryngologists. In this review, clinical features and surgical or nonsurgical treatment options will be discussed.

Abstract

Recurrent respiratory papillomatosis (RRP) is benign neoplasm caused by human papillomavirus. Although RRP arises in anywhere along the airway, the most common site is larynx. RRP has bimodal onset during either childhood or adulthood. Childhood-onset RRP is presented with more aggressive disease, which is associated with higher recurrence rate and spread to distal airway. At present, there is no single modality to eradicate RRP. The current standard treatment is repeated surgical removal of papilloma and preservation of normal structures as far as possible. When repeated surgery is needed more than 4 times per year or disease involves the distal airway, nonsurgical adjuvant therapies should be considered. Several adjuvant therapies have been tried and some showed effectiveness for advanced RRP. Because of its severe impact on children’s heath, latest knowledge of RRP is essential to otolaryngologists. In this review, clinical features and surgical or nonsurgical treatment options will be discussed.

참고문헌 (46)

  1. Derkay CS, "Recurrent respiratory papillomatosis: a review", Laryngoscope, 118(7), pp.1236~1247 (2008)
  2. Wiatrak BJ, "Recurrent respiratory papillomatosis: a longitudinal study comparing severity associated with human papilloma viral types 6 and 11 and other risk factors in a large pediatric population", Laryngoscope, 114(11 Pt 2 Suppl 104), pp.1~23 (2004)
  3. Münger K, "Mechanisms of human papillomavirus-induced oncogenesis", J Virol, 78(21), pp.11451~11460 (2004)
  4. Vambutas A, "Laryngeal papilloma cells have high levels of epidermal growth factor receptor and respond to epidermal growth factor by a decrease in epithelial differentiation", Cancer Res, 53(4), pp.910~914 (1993)
  5. Abramson AL, "Laryngeal papillomatosis:clinical, histopathologic and molecular studies", Laryngoscope, 97(6), pp.678~685 (1987)
  6. Smith EM, "Human papillomavirus infection in papillomas and nondiseased respiratory sites of patients with recurrent respiratory papillomatosis using the polymerase chain reaction", Arch Otolaryngol Head Neck Surg, 119(5), pp.554~557 (1993)
  7. Shah KV, "Risk factors for juvenile onset recurrent respiratory papillomatosis", Pediatr Infect Dis J, 17(5), pp.372~376 (1998)
  8. Snowden RT, "The predictive value of serum interleukins in recurrent respiratory papillomatosis:a preliminary study", Laryngoscope, 111(3), pp.404~408 (2001)
  9. Marsico M, "Estimating the incidence and prevalence of juvenile-onset recurrent respiratory papillomatosis in publicly and privately insured claims databases in the United States", Sex Transm Dis, 41(5), pp.300~305 (2014)
  10. Campisi P, "The epidemiology of juvenile onset recurrent respiratory papillomatosis derived from a population level national database", Laryngoscope, 120(6), pp.1233~1245 (2010)
  11. Omland T, "Epidemiological aspects of recurrent respiratory papillomatosis: a population-based study", Laryngoscope, 122(7), pp.1595~1599 (2012)
  12. Schraff S, "American Society of Pediatric Otolaryngology members’ experience with recurrent respiratory papillomatosis and the use of adjuvant therapy", Arch Otolaryngol Head Neck Surg, 130(9), pp.1039~1042 (2004)
  13. Dedo HH, "CO(2) laser treatment in 244 patients with respiratory papillomas", Laryngoscope, 111(9), pp.1639~1644 (2001)
  14. Kashima HK, "Polymerase chain reaction identification of human papillomavirus DNA in CO2 laser plume from recurrent respiratory papillomatosis", Otolaryngol Head Neck Surg, 104(2), pp.191~195 (1991)
  15. Rees CJ, "Patient tolerance of in-office pulsed dye laser treatments to the upper aerodigestive tract", Otolaryngol Head Neck Surg, 134(6), pp.1023~1027 (2006)
  16. Pasquale K, "Microdebrider versus CO2 laser removal of recurrent respiratory papillomas: a prospective analysis", Laryngoscope, 113(1), pp.139~143 (2003)
  17. El-Bitar MA, "Powered instrumentation in the treatment of recurrent respiratory papillomatosis: an alternative to the carbon dioxide laser", Arch Otolaryngol Head Neck Surg, 128(4), pp.425~428 (2002)
  18. Van Cutsem E, "Successful treatment of a squamous papilloma of the hypopharynx-esophagus by local injections of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine", J Med Virol, 45(2), pp.230~235 (1995)
  19. Broekema FI, "Side-effects of cidofovir in the treatment of recurrent respiratory papillomatosis", Eur Arch Otorhinolaryngol, 265(8), pp.871~879 (2008)
  20. Chadha NK, "Antiviral agents for the treatment of recurrent respiratory papillomatosis: a systematic review of the Englishlanguage literature", Otolaryngol Head Neck Surg, 136(6), pp.863~869 (2007)
  21. McMurray JS, "Cidofovir efficacy in recurrent respiratory papillomatosis: a randomized, double-blind, placebocontrolled study", Ann Otol Rhinol Laryngol, 117(7), pp.477~483 (2008)
  22. "Direct healthcare professional communication regarding serious adverse reactions following off-label use of Vistide"[URL]
  23. Derkay CS, "Current use of intralesional cidofovir for recurrent respiratory papillomatosis", Laryngoscope, 123(3), pp.705~712 (2013)
  24. Armbruster C, "Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b", Eur Respir J, 17(4), pp.830~831 (2001)
  25. Essman EJ, "Estrogen binding sites on membranes from human laryngeal papilloma", Int J Cancer, 33(1), pp.33~36 (1984)
  26. Newfield L, "Estrogen metabolism and human papillomavirus-induced tumors of the larynx: chemo-prophylaxis with indole-3-carbinol", Anticancer Res, 13(2), pp.337~341 (1993)
  27. Rosen CA, "Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results", J Voice, 18(2), pp.248~253 (2004)
  28. Leventhal BG, "Randomized surgical adjuvant trial of interferon alfa-n1 in recurrent papillomatosis", Arch Otolaryngol Head Neck Surg, 114(10), pp.1163~1169 (1988)
  29. Healy GB, "Treatment of recurrent respiratory papillomatosis with human leukocyte interferon. Results of a multicenter randomized clinical trial", N Engl J Med, 319(7), pp.401~407 (1988)
  30. Leventhal BG, "Long-term response of recurrent respiratory papillomatosis to treatment with lymphoblastoid interferon alfa-N1. Papilloma Study Group", N Engl J Med, 325(9), pp.613~617 (1991)
  31. 남해성, "Efficacy of Long-term Interferon-alpha Therapy in Adult Patients with Recurrent Respiratory Papillomatosis", Tuberculosis and Respiratory Diseases, 65(5), pp.390~395 (2008), 대한결핵및호흡기학회
  32. 김기욱, "인터페론 치료로 호전을 보인 재발성 유두종증 1예", Tuberculosis and Respiratory Diseases, 54(3), pp.346~352 (2003), 대한결핵및호흡기학회
  33. Rahbar R, "Role of vascular endothelial growth factor-A in recurrent respiratory papillomatosis", Ann Otol Rhinol Laryngol, 114(4), pp.289~295 (2005)
  34. Zeitels SM, "Microlaryngoscopic and office-based injection of bevacizumab (Avastin) to enhance 532-nm pulsed KTP laser treatment of glottal papillomatosis", Ann Otol Rhinol Laryngol Suppl, 201, pp.1~13 (2009)
  35. Maturo S, "Use of 532-nm pulsed potassium titanyl phosphate laser and adjuvant intralesional bevacizumab for aggressive respiratory papillomatosis in children: initial experience", Arch Otolaryngol Head Neck Surg, 136(6), pp.561~565 (2010)
  36. Zeitels SM, "Local injection of bevacizumab (Avastin) and angiolytic KTP laser treatment of recurrent respiratory papillomatosis of the vocal folds: a prospective study", Ann Otol Rhinol Laryngol, 120(10), pp.627~634 (2011)
  37. Endres DR, "Acyclovir in the treatment of recurrent respiratory papillomatosis. A pilot study", Ann Otol Rhinol Laryngol, 103(4 Pt 1), pp.301~305 (1994)
  38. McGlennen RC, "Pilot trial of ribavirin for the treatment of laryngeal papillomatosis", Head Neck, 15(6), pp.504~512 (1993)
  39. Balauff A, "Successful ribavirin therapy for life-threatening laryngeal papillomatosis post liver transplantation", Pediatr Transplant, 5(2), pp.142~144 (2001)
  40. Pashley NR, "Can mumps vaccine induce remission in recurrent respiratory papilloma?", Arch Otolaryngol Head Neck Surg, 128(7), pp.783~786 (2002)
  41. Wu R, "Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomas", Mol Med, 13(3-4), pp.143~150 (2007)
  42. Shikowitz MJ, "Efficacy of DHE photodynamic therapy for respiratory papillomatosis:immediate and long-term results", Laryngoscope, 108(7), pp.962~967 (1998)
  43. Shikowitz MJ, "Clinical trial of photodynamic therapy with meso-tetra (hydroxyphenyl) chlorin for respiratory papillomatosis", Arch Otolaryngol Head Neck Surg, 131(2), pp.99~105 (2005)
  44. Garland SM, "Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases", N Engl J Med, 356(19), pp.1928~1943 (2007)
  45. McKenna M, "Extraesophageal acid reflux and recurrent respiratory papilloma in children", Int J Pediatr Otorhinolaryngol, 69(5), pp.597~605 (2005)
  46. Holland BW, "Laryngopharyngeal reflux and laryngeal web formation in patients with pediatric recurrent respiratory papillomas", Laryngoscope, 112(11), pp.1926~1929 (2002)

관련 논문AI추천

재발성 호흡기 유두종증의 예방과 보조 요법이동근대한후두음성언어의학회 · 대한후두음성언어의학회지2020 · 제31권 제1호Treatment of Recurrent Respiratory Papillomatosis Using Laser and Available Adjuvant Therapies우승훈, 이상준, Phil-Sang Chung대한의학레이저학회 · Medical Lasers2020 · 제9권 제2호보조적 인유두종바이러스 백신 접종으로 관해된 재발성 호흡기 유두종증 1예박재민, 조정해대한후두음성언어의학회 · 대한후두음성언어의학회지2025 · 제36권 제3호폐 침범을 동반한 상기도의 재발성 호흡기 유두종증 소아 환자에서 정맥 내 시도포비어 사용 1예김수경, 김예진, 김지현, 손영익, 안강모, 원주연, 이지원, 전태연, 조종호, 한정호대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2022 · 제10권 제1호Estimated incidence of juvenile-onset recurrent respiratory papillomatosis in Korea기모란, 오진경, 한민지, Choi Hwa Young, Jung Yuh-Seog, Lee Sang Joon한국역학회 · Epidemiology and Health2021 · 제43권 진성대의 균상 유두종과 공존한 가성대에 발생한 반전성 유두종 1예고소영, 김승우, 문성규, 이미지대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2023 · 제66권 제7호

이 간행물의 다른 논문 (8건)

부비동염에 의해 유발된 후각소실 연구를 위한 생쥐 모델정용기pp. 815-821두부 외상 후 발생한 양성돌발성 두위현훈의 임상 양상심대보, 송미현, 고경민, 박진우, 이준희pp. 836-840정상 청력인 노인과 젊은 성인에서 고음역 감각신경성 난청이 청각의 시간적 해상도에 미치는 영향: Gaps-In-Noise 검사 수행력윤상원, 심현준, 이은섭, 안용휘, 강용경pp. 841-847컴퓨터단층촬영을 이용한 이관과 내경동맥의 해부학적 위치 관계정재훈, 고의경, 공수근, 오세준, 정재환, 이일우pp. 848-854한국인에서 오노디 세포의 유병률에 대한 영상학적 연구강용경, 이승주, 이은섭, 김지선pp. 855-858
원문 보기