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Hearing Outcomes and Prognostic Factors in Idiopathic Sudden Sensorineural Hearing Loss Patients with Combined Intratympanic and Systemic Steroid Therapy

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Background and Objectives Hearing outcomes and prognostic factors of idiopathic suddensensorineural hearing loss (SSNHL) were investigated in patients who underwent combinedintratympanic and systemic steroid therapy. Subjects and Method This study was performed by retrospective chart review. Clinicaloutcomes and prognostic factors were evaluated in 147 patients who received intratympanicsteroid plus systemic steroid therapy. Results Complete hearing recovery was achieved in 36.7% (n=54) of the patients, partialrecovery in 12.9% (n=19), slight recovery in 12.3% (n=18), and total recovery in 61.9% (n=91). Age was identified as an independent, negative prognostic factor for hearing recovery. The recoveryrates of the down sloping and profound types were poorer than those of the up slopingtype as determined by audiography. Conclusion The results of this study suggest that the combined treatment of intratympanicand systemic steroids for idiopathic SSNHL results in high hearing recovery rates, and that thedown-sloping and profound types of audiogram patterns and age are negative prognostic factors.

Abstract

Background and Objectives Hearing outcomes and prognostic factors of idiopathic suddensensorineural hearing loss (SSNHL) were investigated in patients who underwent combinedintratympanic and systemic steroid therapy. Subjects and Method This study was performed by retrospective chart review. Clinicaloutcomes and prognostic factors were evaluated in 147 patients who received intratympanicsteroid plus systemic steroid therapy. Results Complete hearing recovery was achieved in 36.7% (n=54) of the patients, partialrecovery in 12.9% (n=19), slight recovery in 12.3% (n=18), and total recovery in 61.9% (n=91). Age was identified as an independent, negative prognostic factor for hearing recovery. The recoveryrates of the down sloping and profound types were poorer than those of the up slopingtype as determined by audiography. Conclusion The results of this study suggest that the combined treatment of intratympanicand systemic steroids for idiopathic SSNHL results in high hearing recovery rates, and that thedown-sloping and profound types of audiogram patterns and age are negative prognostic factors.

참고문헌 (16)

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