안진검사에서 안구간대경련을 보인 혈청 음성 신생물딸림신경증후군 2예
Two Cases of Seronegative Paraneoplastic Neurologic Syndrome with Opsoclonus Nystagmus
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초록
The dizziness associated with paraneoplastic neurologic syndrome is hard to diagnose clinicallybecause the prevalence of disease is rare, and radiologic and serologic examination resultmay come out normal. Opsoclonus-myoclonus symdrome is a representative of classical paraneoplasticneurologic syndromes. In this paper, we report 2 cases of paraneoplastic neurologicsyndromes with negative serologic auto-antibody test and no brain lesion on MRI. Both caseswere eventually diagnosed through PET. Patients with opsoclonus-myoclonus type nystagmusshould be evaluated for paraneoplastic neurologic syndrome even if their radiologic and serologicfindings are normal.
Abstract
The dizziness associated with paraneoplastic neurologic syndrome is hard to diagnose clinicallybecause the prevalence of disease is rare, and radiologic and serologic examination resultmay come out normal. Opsoclonus-myoclonus symdrome is a representative of classical paraneoplasticneurologic syndromes. In this paper, we report 2 cases of paraneoplastic neurologicsyndromes with negative serologic auto-antibody test and no brain lesion on MRI. Both caseswere eventually diagnosed through PET. Patients with opsoclonus-myoclonus type nystagmusshould be evaluated for paraneoplastic neurologic syndrome even if their radiologic and serologicfindings are normal.
참고문헌 (12)
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